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04:03 AM
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Warning about Methylprednisolone (Drug of Death)
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In accordance with industry accepted best practices we ask that users limit their copy / paste of copyrighted material to the relevant portions of the article you wish to discuss and no more than 50% of the source material, provide a link back to the original article and provide your original comments / criticism in your post with the article.
[quote:Anonymous Coward 26048166:MV8yMDQyMzQ4XzM0NDM5NjYzXzgwQkYxQzFC] [quote:Anonymous Coward 23863188:MV8yMDQyMzQ4XzM0NDM5MDUxXzQxMTE1MjQ2] I am sorry about your son, but am very thankful that you are shedding light on this horrible drug. My [b]11 yr old son[/b] was given this drug about 3 weeks ago for asthmatic bronchitis. He has never before had asthma and was prescribed 60 mg a day. At one point he was told to double his dose...40mg at a time. After 8 days of this medication we were told to stop it abruptly. He was showing signs of arthritic pains and 'moon face'. His joints all ached and popped. He also had a very bad migraine, itching, and terrible abdominal cramping. After numerous trips to both the ER and Physicians office we were told it was post-viral arthritis, heartburn, constipation, etc. etc. I still believe that all of his side effects were due to this medication. He missed almost 3 weeks of school. [/quote] Sounds like your son was in withdrawal. If I had not experienced it, and (though too late) researched it, I would have not known what it was. Many are cut off cold turkey, and then, when the patient is ill, the physicians try to state it's something else. Steroid withdrawal is not familiar with many drs, as well, they are very uneducated about it. I hope your son made a full recovery :hf: [/quote]
Original Message
Corticosteroid withdrawal....
Use of high-dose steroids "for more than a week" begins to produce suppression of the patient's adrenal glands because the exogenous glucocorticoids suppress hypothalamic corticotropin-releasing hormone (CRH) and pituitary adrenocorticotropic hormone (ACTH). With prolonged suppression, the adrenal glands atrophy (physically shrink), and can take months to recover full function after discontinuation of the exogenous glucocorticoid. During this recovery time, the patient is vulnerable to adrenal insufficiency during times of stress,such as illness.
The most serious side effect occurs after the adrenal glands cease natural production of cortisol, which methylprednisolone will replace. Abrupt cessation of the drug after this occurs can result in a condition known as Addisonian crisis, which can be fatal.
Having natural Cortisol depleted on a cold turkey dose quit the person under the drug withdrawal can commit suicide under the psycological stress the withdrawal produces ..
My son Emmanuel on 11/1/2012 commited suicide ..
Emmanuel dose was not steped down, his dose was cut cold turkey causing a drop in natural cortisol that aparently led to a crisis he tried to scape by suicide.
The intent of this post is to warn others about the harmfull effects this drug produces and to investigate if similar cases has happened to others ..
Emmanuel Was 20 years at his death ...
A young man with great promise hopes & dreams truncated by a drug he was not able to handle and us his parents had no information on its withdrawal effects .
Pining will be greatly aprecciated so others get informed.
Thanks me his father ...
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