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Chelation therapy?
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[quote:one who knows 101516:MV8yNDM5NzhfNDM5NTQ0Ml9BMjZCRkRCOQ==] Nope, can't work as advertised. Yes, EDTA chelates heavy metals, we use it in blood tubes to bind calcium and prevent blood clotting when a tube is collected. But...the free ionized calcium in our bloodstream is controlled in a very narrow range...too low or high is death. The calcium which binds to cholesterol ester molecules in atheromatous plaque is INSIDE the cell wall and is bound to the ester with a covalent chemical bond (e.g. think of super glue of the calcium ion to the cholesterol ester). If EDTA is put into the bloodstream it will bind the free floating calcium ions (or magnesium) as fast as possible ---- NOT go into the cell wall and rip a calcium ion off an ester molecule!! If you did give enough EDTA to have any real effect you would bind the blood Ca and result in death (considered a bad outcome!) Most of the "studies" were not double blinded controlled studies. Furthermore, most people scared enough to submit to chelation therapy ALSO make some lifestyle changes: quit smoking, change diet, exercise more, etc., etc., all of which have dramatically significant effects on cardiovascular event rates. You would have to design a trial with two groups with similar high risk lifestyles - one gets a placebo and the other chelation and neither patient or administering doc knows which - follow them for 5 years and see if the group which really received the chelation had a statistically lower event rate. That study DOES NOT EXIST and now would be unethical to do because the groups could not receive aspirin, statin drugs etc. that reduce heart attack rates by 40% alone. (Bye the way, this is OLD HAT stuff that has been around for several decades and became repopularized about 30 years ago when Laetrile infusion clinics sprung up in Mexico to cure all cancers! Remember Steve McQueen? Laetrile didn't work either.) [/quote]
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Does this stuff work? I've read articles saying it's good for you, others saying it does nothing to help you at all. Have any of you ever tried it? The suppositories are cheap and are supposed to be as good as the i.v. but they are suppositories. So any help or opinions here? I'm in pain.
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