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** OCD is Linked to STREP THROAT

 
Anonymous Coward
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03/14/2010 12:14 AM
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** OCD is Linked to STREP THROAT
[link to behavioural-psychology.suite101.com]


OCD Linked to Strep Throat
Obsessive-Compulsive Disorder Symptoms May Develop After Infection
May 16, 2007 Elizabeth Richards

PANDAS, an acronym for the illness, can develop suddenly as symptoms of obsessive-compulsive disorder (OCD), Tourette's syndrome, or nervous tics after a strep infection.



Studies show that antibodies that are suppose to attack streptococcal infections mistakenly attack a brain enzyme and disrupt neuron interaction in children's brains. Researches at the National Institute of Health and collaborators at two universities have confirmed the likely method in which bacterial infections can trigger obsessive-compulsive disorder as well as symptoms of Tourette's syndrome and nervous tics.

PANDAS, short for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptoccocal Infections, occurs suddenly after a strep infection. Symptoms wax and wane but can reoccur with tenacity if a child develops another strep infection.

As children's fight off a strep infection, their immune systems create antibodies that will fight germs. Instead of targeting the strep bacteria, the antibodies will sometimes attack the part of the brain that controls movement. How the antibodies cross the blood-brain barrier is a mystery and still being studied.

Dr. Swedo of the National Institute of Mental Health, Drs. Kirvan and Snider at California State University and Dr. Cunningham of Oklahoma University reported in the July 2006 issue of Journal of Neuroimmunology that in their recent study, all patients with movement disorder had a higher level of the strep antibody that disrupts brain activity.

Symptoms of OCD include repeating behaviors (such as constant hand washing), dwelling on negative or irrational thoughts, and excessive worrying. Sudden, uncontrollable movements and irrepressible speech are associated with Tourette's and nervous tics.


Why do some children develop PANDAS after strep infections and other children do not? Swedo and other researches have shown that a specific antigen was significantly higher in individuals with clinical symptoms than in healthy children. Our immune systems detect antigens and develop antibodies to fight them off. The research indicates that there is a connection between the elevated antigens in PANDAS patients.

Much about PANDAS remains a mystery and research continues. Obsessive-Compulsive Disorder will often persist unrecognized as many patients tend to be secretive or embarrassed about their symptoms. Some children who have had multiple strep infections may demonstrate ongoing symptoms of OCD.

OCD and Strep Diagnostic Criteria
There is currently no test to determine PANDAS. Physicians rely on diagnostic evaluation for the disorder. The five criteria are:

• Presence of OCD and/or a tic disorder

• Pediatric onset (age 3 through puberty)

• Periodic course of symptom severity

• Association of group A Beta-hemolytic streptococcal infection, either a positive throat culture or history of Scarlet Fever

• Association of neurological abnormalities (movements, hyperactivity)

Because PANDAS is relatively new and still not fully understood, traditional treatment for OCD and other affected disorders are still considered best. New medications and therapies are being tested through clinical trials and studies.

Conventional treatment of Obsessive-Compulsive Disorder includes Cognitive Behavioral Therapy (CBT) and pharmacology. Some doctors will use nutritional supplements to compliment treatment. CBT uses imagery and other techniques to change distorted thoughts and perceptions. Medications can be prescribed in addition to CBT or sometimes alone. Different treatments work better for different children, but Cognitive-Behavioral Therapy seems to be the initial treatment of choice.

The sudden onset of OCD or movement disorder symptoms, especially after a strep infection, may indicate the need for evaluation by a physician.



Read more at Suite101: OCD Linked to Strep Throat: Obsessive-Compulsive Disorder Symptoms May Develop After Infection [link to behavioural-psychology.suite101.com]
Anonymous Coward
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03/14/2010 12:18 AM
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Re: ** OCD is Linked to STREP THROAT
Wow.
Anonymous Coward
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03/14/2010 12:19 AM
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Re: ** OCD is Linked to STREP THROAT
Good find OP.


ScienceDaily (Aug. 13, 2009) — A new study by researchers at Columbia University Mailman School of Public Health's Center for Infection and Immunity indicates that pediatric obsessive-compulsive disorder (OCD), Tourette syndrome and/or tic disorder may develop from an inappropriate immune response to the bacteria causing common throat infections.

The mouse model findings, published online by Nature Publishing Group in this week's Molecular Psychiatry, support the view that this condition is a distinct disorder, and represent a key advance in tracing the path leading from an ordinary infection in childhood to the surfacing of a psychiatric syndrome. The research provides new insights into identifying children at risk for autoimmune brain disorders and suggests potential avenues for treatment.

OCD and tic disorders affect a significant portion of the population. More than 25% of adults and over 3% of children manifest some features of these disorders. Until now, scientists have been unable to convincingly document the association between the appearance of antibodies directed against Group A beta-hemolytic streptoccoccus (GABHS) in peripheral blood and the onset of the behavioral and motor aspects of the disorder. As a result, treatment strategies were restricted to targeting symptoms rather than causes.

[link to www.sciencedaily.com]
Anonymous Coward
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03/14/2010 12:24 AM
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Re: ** OCD is Linked to STREP THROAT
Very interesting thanks!
Anonymous Coward
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12/03/2012 01:38 AM
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Re: ** OCD is Linked to STREP THROAT
Makes sense. I can't even COUNT how many times I've had strep throat this year.
McBright
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12/03/2012 08:53 AM
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Re: ** OCD is Linked to STREP THROAT
It's not ok if you get strepthroat once.
McBright
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12/03/2012 08:54 AM
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Re: ** OCD is Linked to STREP THROAT
Must be twice.

Or 4 times.

Or 8.

Must.
AlcoholicRunner
I abduct humans and drink at the same time.

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12/03/2012 08:58 AM

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Re: ** OCD is Linked to STREP THROAT
Root cause is vitamin D deficiency. If your body had enough vitamin D, you wouldn't have gotten strep throat. I highly doubt that strep throat has to do with OCD. More like, OCD had to do with vitamin D. Strep throat is just a symptom of a problem like vitamin D deficiency.

[link to www.psychologytoday.com]
scorpio66

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12/03/2012 08:59 AM
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Re: ** OCD is Linked to STREP THROAT
as soon as i make sure the front door is locked, i'll tell you about all the strep throat i had as a kid

ok, wait, let me just go make the sure the front door is locked

so, when i was little...

wait, i need to go check the front door, brb
AlcoholicRunner
I abduct humans and drink at the same time.

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12/03/2012 09:01 AM

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Re: ** OCD is Linked to STREP THROAT
Makes sense. I can't even COUNT how many times I've had strep throat this year.
 Quoting: Anonymous Coward 18152099


Take 5,000 IU of vitamin D3 a day and watch strep throat disappear...
BRIEF
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User ID: 381742
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12/03/2012 09:04 AM

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Re: ** OCD is Linked to STREP THROAT
as soon as i make sure the front door is locked, i'll tell you about all the strep throat i had as a kid

ok, wait, let me just go make the sure the front door is locked

so, when i was little...

wait, i need to go check the front door, brb
 Quoting: scorpio66


1rof1
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Heterosexual pride!

Briefcut4892
Anonymous Coward
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12/03/2012 09:56 AM
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Re: ** OCD is Linked to STREP THROAT
color me confused, I thought that was when you got your prince albert stuck....

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