Godlike Productions - Conspiracy Forum
Users Online Now: 6,685 (Who's On?)Visitors Today: 2,410,178
Pageviews Today: 3,285,042Threads Today: 5,017Posts Today: 14,560
09:30 PM


Rate this Thread

Absolute BS Crap Reasonable Nice Amazing
 

<<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>

 
arkay (OP)

User ID: 944501
Australia
09/25/2012 11:58 PM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Treyfish has been diligently keeping us informed with news of this new coronavirus that has emerged from Saudi Arabia, and for that we are indebted to him.

He has his own web site and has more news there on this new virus, so in the interests of keeping right up to date on all the details readers really should visit the link below.

News there now is showing that this virus may also now be in Denmark, where there have been some hospitilizations with this suspected virus.

Heres Treyfish's site...

[link to swineflumagazine.blogspot.com.au]
arkay (OP)

User ID: 944501
Australia
09/26/2012 12:05 AM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
This next article from India, describing "one in four people in Delhi as suffering from influenza".

These are the perfect conditions that could see a serious outbreak of H1N1, which is currently active in certain reginons of India.

Flu capital: One in four Delhiites down with influenza
HT Correspondent, Hindustan Times
New Delhi, September 26, 2012 Email to Author

First Published: 00:36 IST(26/9/2012)
Last Updated: 00:37 IST(26/9/2012)

High fever, runny nose, headache and sore throat - one in four Delhittes is down with flu these days. Thanks to the delayed monsoon and the sudden dip in temperature, viruses are wreaking havoc on the health of residents in the national Capital.

"There is a spurt in the cases of viral pneumonia and upper respiratory tract infections. Post-monsoon, we usually expect a rise in such cases but this time it has been unusually high," said Dr Monica Mahajan, senior consultant, department of medicine at Max Healthcare, Saket.

"There is a clustering of cases in households where one family member becomes the primary patient and then others get infected," she said.


Link here...

[link to www.hindustantimes.com]
arkay (OP)

User ID: 944501
Australia
09/26/2012 12:22 AM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
The following is a Press Release from the Health Protection Agency of Britan in relation to the new coronavirus detection.

Acute respiratory illness associated with a new virus identified in the UK
23 September 2012

The Health Protection Agency (HPA) can confirm the diagnosis of one laboratory confirmed case of severe respiratory illness associated with a new type of coronavirus. The patient, who is from the Middle East and recently arrived in the UK, is receiving intensive care treatment in a London hospital.



In recent months, this new human coronavirus was also identified in a patient with acute respiratory illness in Saudi Arabia, who subsequently died.

Coronaviruses are causes of the common cold but can also include more severe illness, such as the virus responsible for SARS (Severe Acute Respiratory Syndrome). This new virus, however, is different from any that have previously been identified in humans. Preliminary enquiries have revealed no evidence of illness in contacts of these two cases, including healthcare workers. Based on what we know about other coronaviruses, many of these contacts will already have passed the period when they could have caught the virus from the infected person.

We are also aware of a small number of other cases of serious respiratory illness in the Middle East in the past three months, one of whom was treated in the UK but has since died. This person's illness is also being investigated although there is no evidence at present to suggest that it is caused by the same virus or linked to the other two cases. No other confirmed cases have been identified to date in the UK.

Professor John Watson, head of the respiratory diseases department at the HPA, said: "The HPA is providing advice to healthcare workers to ensure the patient under investigation is being treated appropriately.

"In the light of the severity of the illness that has been identified in the two confirmed cases, immediate steps have been taken to ensure that people who have been in contact with the UK case have not been infected, and there is no evidence to suggest that they have.

"Further information about these cases is being developed for healthcare workers in the UK, as well as advice to help maintain increased vigilance for this virus. This information is also being shared with national and international authorities including the World Health Organization and the European Centre for Disease Control.

"As we are aware of only two cases worldwide and there is no specific evidence of ongoing transmission, at present there is no specific advice for the public or returning travellers to take but we will share any further advice with the public as soon as more information becomes available."


Link here...

[link to www.hpa.org.uk]

On that Press release page toward the bottom, there is another link that takes readers to a Q&A Info sheet that answers many questions regarding this virus, and is well worth the read.

Link here...

[link to www.hpa.org.uk]
Treyfish

User ID: 14756837
United States
09/26/2012 09:21 AM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
the CDC is aaaaful quiet..
[link to www.cdc.gov]
[link to wwwnc.cdc.gov]
[link to twitter.com (secure)]
Treyfish

User ID: 14756837
United States
09/26/2012 10:04 AM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
The five persons admitted for observation for corona virus at Odense University Hospital can breathe a sigh of relief [link to www.dr.dk]
Treyfish

User ID: 14756837
United States
09/26/2012 10:55 AM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Patients have not feared virus
Wednesday on 26th September 2012 kl. 16:04


The five patients who yesterday was admitted to Odense University Hospital with symptoms of a new virus that has not been affected by the coronavirus, the state consultant at Department of Infectious Diseases at the University Hospital Svend Stensvang to tv2.dk.

"They have all five influenza B and it fits completely fine with the clinical picture they had. One expects namely the corona virus is much more visible," he says.
Neither patient at Hvidovre Hospital is infected with coronavirus. Also in this case it was about an ordinary flu, says consultant at Statens Serum Institut, Thyra Krause to tv2.dk. [link to nyhederne.tv2.dk]
Anonymous Coward
User ID: 24467782
United Kingdom
09/26/2012 02:54 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
*****************

When the H1N1 brroke out in April 2009 we were told that it would bring the world to its knees.

However, my son who is a Doctor of Pharmacy and a VERY wise gentleman told me this . . . "Mom, the H1N1 is a trial run. The BIG ONE will hit us in about three or four years."

We are in 2012 and soon will arrive at 2013; the timing is perfect!!!!!

I think he may have been right******bump
 Quoting: Messenger 24214267


MY fears also .....as I heard similar
Anonymous Coward
User ID: 24467897
United Kingdom
09/26/2012 02:59 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
A New Coronavirus Isolated from Humans
BY VINCENT RACANIELLO

Wednesday, September 26, 2012 at 06:45 AM EDT

A new coronavirus has been isolated from two individuals with severe respiratory illness. It is different from the SARS coronavirus, but health officials are nonetheless preparing for a rapid response should the virus be detected elsewhere.

The novel coronavirus was first reported by Ali Mohamed Zaki on ProMED-mail on 15 September 2012, from a 60 year old male patient in Saudi Arabia with pneumonia and acute renal failure who died in July. The virus was isolated by culturing sputum on Vero and LLC-MK2 cells, and identified as a coronavirus by polymerase chain reaction. Dr. Zaki sent the virus to Ron Fouchier in the Netherlands who sequenced its genome and confirmed that it is a beta-coronavirus closely related to bat coronaviruses.

At the beginning of September 2012 a 49 year old male Qatari national who had previously traveled to Saudi Arabia was admitted to an intensive care unit in Doha with severe respiratory illness. He was moved to the United Kingdom where laboratory tests confirmed the presence of the novel coronavirus. Comparison of a 200 nucleotide genome sequence with that from the Saudi national revealed 99.5% identity (one mismatch). Alignment of this sequence with that of other coronaviruses shows that the new virus is related to bat coronaviruses.

This new virus is not the SARS coronavirus, but because it is related to bat coronaviruses there is concern that it could spread rapidly among humans and cause serious respiratory disease. This is why WHO has placed health officials in its six regions on alert, and has issued a case definition so that the disease may be readily detected. The definition comprises: acute respiratory syndrome which may include fever (&#8805; 38°C , 100.4°F) and cough requiring hospitalization or with suspicion of lower airway involvement (clinical or radiological evidence of consolidation) not explained by any other infection or any other aetiology; and close contact within the last 10 days before onset of illness with a probable or confirmed case of novel coronavirus infection while the case-contact was ill, or travel to or residence in an area where infection with novel coronavirus has recently been reported or where transmission could have occurred.

Ron Fouchier doesn't believe that we should become overly worried about these cases:

There are now six known human coronaviruses; one of them is SARS, but four cause the common cold and are quite innocuous. So let's keep both feet on the ground and not blow this out of proportion.

The fact that the virus has been isolated from individuals with severe respiratory disease does not mean that it is the causative agent. To prove this requires additional work, as Fouchier notes:

For starters, we'll find out whether animals get sick from this virus. You can isolate a virus from a patient, but that does not mean they died from it; to show that it causes disease you need to fulfill Koch's postulates. That's what we did for SARS, and it's what we hope to do here; we've applied for emergency ethical approval. The most obvious animal species to put this virus in are mice, ferrets, and perhaps monkeys.

Proof that the new coronavirus is an agent of respiratory disease would come from its isolation from additional patients with the disease. Apparently a coronavirus has recently been isolated from three individuals with respiratory disease in Saudi Arabia, but it is not known if it is the same virus isolated from the Saudi Arabian male. In addition, an outbreak of severe respiratory disease in Jordan in April of 2012 is now being reviewed for evidence of the novel coronavirus.

Coronaviruses are composed of enveloped virions that contain a negative strand RNA genome. Human coronaviruses may cause the common cold or severe respiratory illness. In 2002 the SARS coronavirus emerged in China and spread globally, infecting over 8000 individuals and killing more than 900. The SARS coronavirus is believed to have originated in bats and spread to humans either directly or through animals in meat markets. Because the new coronavirus isolated from two patients is related to bat coronaviruses, there is concern that a scenario similar to the SARS outbreak is in the making. Whether or not this is true will be revealed in the coming weeks.
Anonymous Coward
User ID: 24467897
United Kingdom
09/26/2012 03:04 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
and following on from above link
COPENHAGEN, Sept 26, 2012 (AFP) -- Five people have been isolated in a hospital in Denmark with symptoms of a new viral respiratory illness from the same family as the deadly SARS virus, the hospital said on Wednesday [ 26 September].

"We have sent samples from the five for testing and hope to get the results this afternoon," chief physician Svend Stenvang Petersen of Odense University Hospital told AFP.

"The five have a fever, coughing and influenza-like symptoms," he added.

Petersen said those admitted were a family of four where the father had been to Saudi Arabia, and an unrelated person who had been to Qatar. Two of those with symptoms were under the age of five.

"We have put them in isolation because we don't know how the virus spreads. So just as with bird and swine flu we have admitted them and isolated them so that we prevent the spread to others," Petersen said.

"We do not have any medicine that works against this virus."

The five contacted their doctors following a Danish health authority advisory on Monday recommending that those who had travelled to Qatar and Saudi Arabia seek medical help if they experienced a fever, coughing, shortness of breath and difficulty breathing.

The new virus, which is in the same family as the Severe Acute Respiratory Syndrome (SARS) virus, was recently identified by the British Health Protection Agency in a Qatari man transferred to London from Qatar.

A Saudi national died earlier this year from a virtually identical virus, the World Health Organisation has said.

The WHO confirmed in a global alert on Monday that the new virus was in the coronavirus family which causes the common cold but can also include more severe illnesses including SARS.

SARS swept out of China in 2003, killing more than 800 people worldwide.


questions remain .....
Anonymous Coward
User ID: 24467897
United Kingdom
09/26/2012 03:06 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to doctorsurgerycenter.com]

original link to story
Anonymous Coward
User ID: 24468785
United Kingdom
09/26/2012 03:15 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to www.zawya.com]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:34 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Saudi Arabia has taken precautions to prevent disease spreading among pilgrims next month after a Qatari man was infected with a virus related to the deadly Sars, a health ministry official said yesterday.
The World Health Organisation put out a global alert on Sunday saying a new, previously unknown, virus had infected a 49-year-old Qatari man who had recently travelled to Saudi Arabia, where another man with an almost identical virus had already died.
Britain’s Health Protection Agency and respiratory disease experts said there was no immediate cause for concern, although authorities were watching for any signs of the virus spreading.
Muslims from some 160 countries flock to Makkah and Madinah during the annual Haj pilgrimage, which begins in late October. Some arrive by plane, others by boat or by car.
“The health ministry has taken preventative measures to deal with the influx of over 2mn Haj pilgrims,” Ziad Memish, the deputy minister for public health, told Reuters.
“The measures include monitoring the entrances through land, sea and air to evaluate the people entering and obtain samples if any symptoms are apparent,” he added.
In 2009 Saudi Arabia set up thermal cameras at its airports and increased the number of its medics as part of its measures to limit the spread of the H1N1 flu. It will not resort to using thermal cameras this year, Memish said.
“There is also continuous monitoring in the holy places in Makkah and Madinah and Jeddah, with teams on the ground and hospitals to deal with them.”
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:42 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Last Updated: Wednesday, November 10, 1433 - Sep 26 2012 KSA 22:11 - GMT 19:11 message from a doctor reveals the beginning of "the mysterious virus Arabia" sent to the World Health Organization details Hospital first infected in Jdhaleravae 10 November 1433 - 26 September 2012 m

Dubai - Mohammed Aliusa
Revealed an exchange of letters between a doctors in the Saudi city of Jeddah and the World Association for Infectious Diseases details mysterious virus of type "crowns" which was announced a few days ago.

While the Ministry of Health issued Arabia assurances that the disease is not serious, but the World Health Organization (WHO) today urged all workers in the medical field to report any patient with severe infection in the respiratory tract.

In one of the messages sent by the doctor from Saudi Arabia to the World Organization revealed the story of the virus details of which began in the city of Jeddah, after the arrival of one of the cases that showed the effects of the flu to a private hospital in the history of 10 of September / current.

And began a medical condition of the patient, who was in the sixty years of age, and was diagnosed as suffering from severe flu and kidney failure.

7 days between the discovery of the situation and disclosure Anhaautam virus isolation for analysis by one of the doctors who specialize in microbiology, to be the first result that this virus is a type of "crowns", and return the doctor to make sure these details by analyzing the virus laboratory specialist in the Netherlands.

Dutch laboratory confirmed that the virus is not influenza types A or B, it is a mysterious virus of the family of "crowns", which belongs to the virus that causes SARS, which killed 800 people nearly 10 years ago.

After approximately seven days announced the Saudi Ministry of Health for the discovery of this virus and caused two deaths and injuring a third person, the World Health Organization (WHO) issued on the same day a global alert about this mysterious virus.

The monitors "health" Saudi Arabia is currently the situation closely, especially with the approach of the pilgrimage season, in addition to the World Health Organization urged all workers in the medical field around the world to report any patient infected with severe respiratory may have traveled to Saudi Arabia or Qatar.
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:46 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
London1_novel CoV 2012.

name of this virus crown type
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:50 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
London1 Novel CoV 2012 nsp12 Coronavirus Sequence
Recombinomics Commentary 01:00
September 26, 2012


The above phylogenetic tree (generated by the UK Health Protection Agency - HPA) is of the partial sequence from the coronavirus polymerase gene (nsp12) from the Qatar case (49M) demonstrates the novel aspect of this cornonavirus (CoV). The HPA used a 208 base pair fragment representing positions 15303-15510 of the closet match, Bat coronovirus HKU5-5, sequenced by researchers at The University of Hong Kong from an isolate from Guangdong Province. The fragment had 35 differences (83% identity), in contrast to the Netherlands sequence from the index case (60M who died in Saudi Arabia), which had 1 difference (99.5% identity).

Thus, the coronavirus is clearly novel and does not match any public coronavirus sequence.

The HPA is to be commended for the rapid release of this important sequence.


[link to www.recombinomics.com]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:52 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Saudi Arabia SARS-CoV Cases Raise Concerns
Recombinomics Commentary 20:45
September 24, 2012

The HPA has compared the sequencing of the virus isolate from the 49 year old Qatari national with that of a virus sequenced previously by the Erasmus University Medical Centre, Netherlands. This latter isolate was obtained from lung tissue of a fatal case earlier this year in a 60 year-old Saudi national. This comparison indicated 99.5% identity, with one nucleotide mismatch over the regions compared.

The above comments from the Health Protection Agency in the UK describe the re-emergence of SARS (Sudden Acute Respiratory Syndrome)-CoV (coronavirus). The HPA has only sequenced 200 BP, which is virtually identical to the same region for the earlier case from Saudi Arabia. The larger sequence from the Netherlands indicates the current virus is related to bat cornonaviruses, which are the same group as the SARS-CoV which emerged in 2002.

In 2002 sequences from SARS-CoV were released almost in real time and were quickly designated as novel. Release of sequences from these two recent (July and September) isolates would be useful.

Media reports have already claimed that these isolates are distinct from the SARS-CoV from 2002/2003, but that distinction is far from clear because of similarities with bat CoV, which has been cited as the natural reservoir for the 2002/2003 outbreaks.
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:54 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to www.hpa.org.uk]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 07:56 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to www.ncbi.nlm.nih.gov]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:00 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to www.hpa.org.uk]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:01 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to healthland.time.com]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:05 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to hygimia69.blogspot.co.uk]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:06 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
[link to hygimia69.blogspot.co.uk]
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:11 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Wisconsin Mink H3N2v Matches 2011 Human Cases
Recombinomics Commentary 23:45
September 26, 2012

The USDA has released a full set of H3N2v sequences from a Wisconsin mink isolate, A/mink/Wisconsin/31512-7/2012, which matches H3N2v cases from 2011. The sample was collected on August 14 and deposited at Genbank on August 30, signaling a high priority by the USDA.

Although details surrounding the detection of this infection are not know, this recent isolate extends to spread of this sub-clade, which has been frequently detected in swine, including a July 21 collection from Illinois, A/swine/Illinois/A01203672/2012, as well as June isolates from Ohio (A/swine/Ohio/1/2012, A/swine/Ohio/6/2012, A/swine/Ohio/7/2012, A/swine/Ohio/9/2012).

Although this sub-clade is common and widespread in swine, including Ohio and Indiana where most of the recent human H3N2v cases were isolated, none of these swine (or mink) infections have produced a reported human case in 2012.

The most recent human cases with this sub-clade were in the 2011 Iowa cluster (which had no swine exposure) in November. Since that outbreak the CDC has released 60 sets of H3N2v sequences and all 60 matched the sub-clade identified at the West Virginia day care center in November / December. 2011.
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:13 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Saudi Arabia SARS-CoV Case Fatality Rate Raises Concerns
Recombinomics Commentary 13:00
September 25, 2012

We are also aware of a small number of other cases of serious respiratory illness in the Middle East in the past three months, one of whom was treated in the UK but has since died.

The above comments from the UK Health Protection Agency increases concerns based on a high case fatality rate (CFR) for the novel SARS-CoV confirmed in two cases (60M and 49M). Although the above fatal case has not been SARS-CoV confirmed, the similarity with the current case (infected in the Middle East and flown to the UK for treatment) raises concerns that the above fatal case and the current critical case may be related.

The index case (60M) showed symptoms three months ago and died in Saudi Arabia, but the critical case is much more current (developed symptoms in Qatar on September 3 after travel to Saudi Arabia) and the disease onset dates for the “other cases of serious respiratory illness in the Middle East” has not been released. However, confirmation of SARS-CoV in the above fatal case would produce a CFR of 67%, which would be a significant concern.

More detail on the above fatal case, as well as the additional cases under investigation, (including, symptoms, disease onset dates, and locations) would be useful.
Anonymous Coward
User ID: 24481852
United Kingdom
09/26/2012 08:16 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Saudi Arabia SARS-CoV Closely Related To Bat Coronaviruses
Recombinomics Commentary 23:15
September 24, 2012

The virus RNA was tested also in Dr. Ron Fouchier's laboratory in the Netherlands and was confirmed to be a new member of the beta group of corononaviruses, closely related to bat coronaviruses.

The above comments from Ali Mohamed Zaki of Dr Fakeeh hospital in Jeddah, Saudi Arabia (as posted at ProMED) indicate the SARS CoV from the fatal case in Saudi Arabia is closely related to the SARS CoV that caused the SARS outbreaks in 2002 and 2003. The more recent case (Qatar via Saudi Arabia was 99.5% identical based on a short sequence of about 200 BP, as noted by the HPA in the UK. This second cases is in critical condition with renal failure, which was also confirmed in the index case. Additional severe cases from the Middle East are under investigation.

The similarities with the 2003 outbreak raise concerns. The international spread in February, 2003 was largely linked to a physician who had been infected after treating cases in Guangdong Province. He came to Hong Kong for a wedding and stayed in room 911 at the Metropole Hotel where he infected multiple visitors / tourists on the 9th floor, who spread the virus to Hong Kong, Singapore, Vietnam (Hanoi), and Canada (Toronto).

The link of the rapid spread outside of mainland China to a single case raises concerns that the two confirmed and multiple suspect cases linked to Saudi Arabia may represent a similar situation. The SARS-CoV from the 2003 outbreak had been infecting patients in Guangdong Province in late 2002, but the Hong Kong physician precipitated the global expansion, raising concerns that the upcoming Hajj in Saudi Arabia may pose a significant world health risk.

Release of the sequences from the labs in the Netherlands and UK would be useful.
arkay (OP)

User ID: 944501
Australia
09/26/2012 11:00 PM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
Well, that is impressive!

Many thanks to Treyfish and our UK anon contributors for this massive swathe of new news mostly concerning the new coronovirus detection in Saudi Arabia.

From the looks of it, Treyfish has found information that would appear to exclude those people who have been in isolation in Denmark.

Apparently their illness is in fact now recognised as flu, so fortunately we can now eliminate them as possible vectors.

And on that note, its important to observe what the experts have so far been asserting.

That this new virus doesent yet appear to be easily spreading from human to human.

There has been sufficient time and sufficient close contacts with the known cases for those contacts to have travelled through the incubation period for this virus and so far, all have remained healthy.

And that is a real blessing.

What is highly re-assuring is the absolute rapid spread of information that has accompanied the news of this new virus.

If we we ever doubted that the world has been desensitized to this type of news then perhaps a look at what has occured with this example should serve to re-assure us all.

There are still many questions that remain unanswered with the emergence and discovery of this new virus.

Things such as where its reservoir lies, being bat like could mean that for the present cases may be rare and only emerge where there has been some direct vectoring from a bat to a human, possibly through contaminated food.

The questions raised that surrounded the Jordonian outbreak that saw several deaths from an unknown source should be one of the first studies to be undertaken as we do know that whatever that bug was, it had acquired H2H transmissability, and if this virus does prove to be the same, then we do indeed have a serious problem to deal with.

But at this point we just do not know, it is very early days and we have to be patient here and allow our medical experts do what they do best.

What vexes me the most is the fact that almost every other week we are seeing new viruses emerging in all sorts of different regions, and that just doesent sit well with me, it has a very unnatural "feel" to it, and as previously stated, while none of them are currently causing a large enough problem individually anywhere, they are still slowly spreading and increasing the liklihood of sooner or later finding the right host to reassort themselves in a way that could easily develop into a deadly pandemic.

It sounds paranoid and I hope that it is me, but the facts are there, and as each day passes the opportunity for that one chance to find the right mutation for some bug to go pandemic, remains.

In the bigger picture, this is exactly how these viruses do mutate, simply by coincidental opportunity and those opportunities are increasing daily.

In the mean time any people travelling or living in these regions simply need to raise their level of awareness, increase their attention to hygene, especially with hand washing and appropriate coughing and sneezing techniques, which will always be hugely helpful in minimizing the free spread of these type of diseases.

This advice is applicable anywhere and at all times anyway.
Anonymous Coward
User ID: 24326290
United States
09/26/2012 11:10 PM
Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
I would imagine that it is possible for these little ones to be sprayed on you as well....from aircraft. Then Baxter telling you that it has some medicine to help you.

Do I need to catch up on my sleep?


Keep up the nice work arkay.....and have a nice week.


David
arkay (OP)

User ID: 944501
Australia
09/26/2012 11:31 PM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
The potential for viruses to reassort themselves and the risks that this potential brings to us in terms of H5N1 finding an opportunity to mutate and pose that threat is highlighted here where H5N2 has indeed shown that it has undergone this reassortment with H5N1, in China.

Four new H5N2 strains identified in China
Chinese researchers detailed four new strains of H5N2 avian flu viruses in PLoS One yesterday, all of which were able to replicate in ducks and mice. The team analyzed the evolution and pathogenicity of the strains, which were isolated from apparently healthy poultry in H5N1-endemic parts of China. Two of these viruses developed when clade 2.3.4 H5N1 viruses reassorted and acquired novel neuraminidase and nonstructural protein genes.


Link here...

[link to www.cidrap.umn.edu]
arkay (OP)

User ID: 944501
Australia
09/26/2012 11:35 PM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
I would imagine that it is possible for these little ones to be sprayed on you as well....from aircraft. Then Baxter telling you that it has some medicine to help you.

Do I need to catch up on my sleep?


Keep up the nice work arkay.....and have a nice week.


David
 Quoting: Anonymous Coward 24326290


Good to see you still here David, and yes it must be late in your neck of the woods.

Best wishes and stay well.

cheers

arkay
arkay (OP)

User ID: 944501
Australia
09/27/2012 12:03 AM

Report Abusive Post
Report Copyright Violation
Re: <<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>
This next article is without doubt the best I have read that refers to H5N1 and its variations and how it is evolving and what and where these evolutionary changes are occuring.

At times the article does get a little technical, but it is written in a way that most lay people can gain a good understanding of this bugs evolution over time and around the world.

Its lengthy, but an excellent compliation of information.

Avian influenza A H5N1 virus: a continuous threat to humans


Kelvin KW To1,2,3, Kenneth HL Ng4, Tak-Lun Que4, Jacky MC Chan5, Kay-Yan Tsang5, Alan KL Tsang2,3, Honglin Chen1,2,3 and Kwok-Yung Yuen1,2,3

1State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong Special Administrative Region, China
2Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Special Administrative Region, China
3Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region, China
4Department of Pathology, Tuen Mun Hospital, Hong Kong Special Administrative Region, China
5Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China
Correspondence: KY Yuen, E-mail: kyyuen@hku.hk

Received 8 May 2012; Revised 11 June 2012; Accepted 16 July 2012

Abstract

We report the first case of severe pneumonia due to co-infection with the emerging avian influenza A (H5N1) virus subclade 2.3.2.1 and Mycoplasma pneumoniae. The patient was a returning traveller who had visited a poultry market in South China. We then review the epidemiology, virology, interspecies barrier limiting poultry-to-human transmission, clinical manifestation, laboratory diagnosis, treatment and control measures of H5N1 clades that can be transmitted to humans. The recent controversy regarding the experiments involving aerosol transmission of recombinant H5N1 virus between ferrets is discussed. We also review the relative contribution of the poor response to antiviral treatment and the virus-induced hyperinflammatory damage to the pathogenesis and the high mortality of this infection. The factors related to the host, virus or medical intervention leading to the difference in disease mortality of different countries remain unknown. Because most developing countries have difficulty in instituting effective biosecurity measures, poultry vaccination becomes an important control measure. The rapid evolution of the virus would adversely affect the efficacy of poultry vaccination unless a correctly matched vaccine was chosen, manufactured and administered in a timely manner. Vigilant surveillance must continue to allow better preparedness for another poultry or human pandemic due to new viral mutants.


Link here...

[link to www.nature.com]

News