<<Advancing Bird Flu-H5N1...Now following MERS and Ebola approaching PANDEMICS>>>

Hi UK anon, youre up very late.

Thank you for all your work, youve been quite prolific today, excellent reading and research.

I guess you are enjoying the last of the nights peace right now.

Thanks heaps

arkay

Last Edited by arkay on 02/28/2013 07:52 PM

Humidity has now been identified to have a significant impact of viral infectivity according to this recent study.

This could provide serious and yet simple assistance with control measures in both the home and also hospital settings among many others, thinking, doctors surgeries, schools, public meeting places, etc, its a massive list.

Study: Aerosolized flu viruses lose more infectivity at higher humidity
Higher indoor humidity may help temper the infectivity of influenza viruses aerosolized during coughing, according to a study yesterday in PLoS One. National Institute for Occupational Safety and Health (NIOSH) researchers used a computerized bellows-type apparatus to simulate five coughs about 1 minute apart, then collected virus particles using NIOSH bioaerosol samplers.

Link here...

[link to www.cidrap.umn.edu]

Folks, I might not get too much added here today.

GLP is having significant server problems and have been down for large periods, so please bare with me, Im sure that they will overcome their issues in good time.

In the mean time I do have to thank both Treyfish and as usual our reliable sleuth UK anon who today has excelled with a huge list of postings to work through.

Thanks again UK anon, you know what this means to us all.

Some small gesture from us all.

arkay

Greece is reporting significant cases of H1N1 swine flu.

While the numbers this year are similar to last years records, mention is being made of their experience and impact of the global financial crisis and the cut backs to services that have been made as a result, which may have contrubuted to these numbers again.

Date: February 28, 2013 Source: Yahoo News,

by Jaime Torres and Jorge González]

Twelve people have died in Greece so far this season because of the flu, most of them infected with the 2009 H1N1 strain, said the Center for Control and Prevention of Communicable Diseases (KEELPNO, for its acronym in Greek) adding that 15 others remain hospitalized.

Since last October until February 21 had registered a total of 42 cases of severe flu, most of them of that variant, the source said in a statement.

The authorities have prevented the alarm trigger and indicated that in the same period last year was similar evolution, with 33 severe cases and eight deaths.

Link here...

[link to www.promedmail.org]

google translated

In one of the posts from UK anon earlier today mention was made as to the developing situation with H1N1 swine flu.

Looking at what is occuring around the globe it appears that the mutated H1N1 strain may have gained a particular advantage to infect more people than was the case with the initial 2009 pandemic, but currently being somewhat restricted to localized regions around the globe.

Notably, in particular regions of very dense populations, which would directly relate to the enhansed contaigen given the strain with the "M" gene. It makes sense that we are witnessing noticeable higher rates of infection in these specific regions.

Further I think that we are witnessing what may well prove to be the second wave of the 2009 pandemic, which would normally be expected to be somewhat milder in impact but with the "M" gene present, making this strain more contagous and then weather and other "natural" influences, we could likely be witnessing a more aggressive impact from this virus, time will tell.

Of greater concern is the new novel coronavirus.

As I recently mentioned, this bug seems to have a few unexpected tricks up its sleeve, so to speak.

We have heard mention for a 60 day incubation period.

We have witnessed a situation where a victim recovered from it, but then relapsed some two weeks after apparent recovery.

So the situation so far is one where it is likely that someone could be suffering from this bug mildly as was reported in Jordan where 2 deaths were reported but dozens more suffering at various levels but recovering.

This could make this bug one of the worst because if these qualities are typical then this coronavirus has the ability to infect but not so severely so as to cause concern which then leads it to be able to spread far and wide virtually undetected until another severe case emerges in a new location and we are left wondering how it vectored in.

I believe that this bug has a relatively low mortality rate overall, but in serious cases that mortality rate escalates up to probably around 50%.

What is unclear at this time are the differences that can allow it to be a mild infection in one person and in other, be a full blown life threatening infection.

Another vexing question that bothers me is the way it can appear to have gone dormant for significant periods, but then can re-emerge with all the veracity that was previously witnessed, only in a completely new location but without any apparent vector.

It really does look as though its natural reservoir will be found to be within the bat communities as these animals can and do travel large distances quickly and from those two factors alone would seem to suggest them to be the logical natural reservoir and vector.

As stated earlier, this bug appears to have a multitude of uncharacteristic traits that could have us chasing our tails for a long time before we get a good understanding of all its capabilities.

And that isnt a pleasent challenge for our researchers to have to face.

Also keep in ming that so far we have no known medical interventions to fight this coronavirus with.

All we do have is sophisticated medical care such as highly technical and not too common mechanical life support aids, of which there will be massive shortages of should there be a serious outbreak anywhere.

From what we have witnessed so far some people have needed to be kept on this equipment for many months at a time.

Who gets the only machines available, is a question I gladly wont have to be making, nor do I envy those who will be charged with those decisions of life and death.

[link to www.flutrackers.com]
lets see what happens in the next sixty days ......

[link to www.biosciencetechnology.com]

bats are mammals and they are close to the birds why is this such a surprize

[link to www.flutrackers.com]

OP .... One must NOT forget the CONTINUOUS intake, via eating, breathing and drinking, of the Fukushima, and other contributors of radiation poisoning that cause the immune system to weaken, as well as 12 more symptoms, among which is FLU LIKE SYMPTOMS !

It's been TWO YEARS NOW, and the amount of release has NOT gone DOWN. PLUS, the pacific oceans fish are now polluted with radiation. The crops from 2012 are loaded with gamma, my survey meter shows, and I had to stop drinking milk, as the GAMMA radiation was TOO high, same as in April 2011.

Eagle

[link to www.virologyj.com]

[link to online.wsj.com]

off topic but equally important to mention

The Nepalese man detained at the U.S. border carries a particularly deadly strain—XDR, "extensively drug-resistant" TB. His TB is resistant to at least eight of the 15 or so standard drugs, according to a U.S. government description of the case reviewed by the Journal. His XDR strain has been seen only once before in the U.S., in another patient of Nepalese origin, according to the government description.

mmm excellent find and good story but this doesent advance us towards any protection unfortunately.

So much work is being done on this problem and far too often we end up with dead ends, but that is the life of our talented researchers, to not give up after they have chased down a good lead only to find a dead end such as this.

This only goes to demonstrate the complee dedication to a calling and an ability to take all the blows just to make a tiny step in the right direction and this is exactly why I support these dedicated saints so much.

Thank you UK anon for grubbing this story out of where it probably would be ignored, again your sharp senses just grab all those tiny little pieces that really are very important in the bigger picture.

You really do amaze even me and after all this time working with you...

I cant find the words...but thank you
arkay

This an excellent summary of what is currently known with regards to the novel coronavirus, but everything points to the cautions that have been aired in this thread.

This is new and it needs to be taken seriously as a new foe.

Far too much is still not understood about this virus and we need to be acutely aware of these factors.

World Wide health officials really should be ramping up their border surveilance protocols immediately or their complacency could be a matter of later serious regret.

Really the saying of a "stitch in time...etc"

or perhaps...keep your friends close but keep your enemies closer...

never underestimate your enemy..if you do it well be too late...

and so on...

Of all this I have little doubt.

It is past time to act with serious determination and resignation, we are now guilty of collective recklessnes in regard to this new threat.

arkay

Thank you for your input and you are completely correct.

Its sad that at this point in time we...the human race seem to be having to deal with so many serious not so good influences all at once, but all we can do is to do our best and to share our positive experiences with others in some type of attempt to at least give guidance to the best avenue that the majority might travel for the best result.

I have no doubt that people like yourself are the leaders that will take that role and one day we will all be indebted to yourself and your kind for the generous gifts of knowledge and help that you shared when we all needed it the most.

Please hang around, your time and our need is close I think.

Excellent documentation of medical facts.

How do you manage to find this stuff???

But thank you...yet again!

Ive spoken before about the re-emergence of TB and the manner in which poor medical supervision and lack of good education have managed to produce this serious threat to us all, in the form of a virtually untreatable strain of TB among several other infections as well...have a look at ghonnerea these days, especially in America and the UK.

Far more care is needed with this bug or all your pleasures will be just memories and real fast.

This is absolutely typical of the lax attitudes and lack of knowledge that most people have to completing any courses of anti-biotic, and it typifies exactly how these dangerous resistant strains of bugs come into being.

We are their creators... GET IT...WE HAVE DONE THIS.

We are the fools that think we know better and become complacent and dont heed all the medical advice that is offered to us.

These problems have been engineered by our stupidity.

For once and for all...

If you are prescribed an anti-biotic, take the whole lot, even when you begin to feel better.

Your feeling better is a result of reducing the bugs effect on you and if you stop early you will probably recover completely because your own defences will finish the job.

But what will happen will be a case of the last of the bugs that made you sick will be exposed to the anti-biotic but wont be fully treated (killed) by it and will continue to live, and in a short time will gain an immunity to it, like you they will get better and recover from your medicine, designed to eradicate them, along with all the rest of anti-biotic exposures that it has previously seen and hence the development of an immune bug.

For Gods sake people, If you are prescribed an anti-biotic take all of it...simple, and it wont hurt you, but it WILL save the world from an untreatable bug.

And that is exactly where we are heading today.

Thanks again UK anon for all your dedication and serious effors that you dedicate for all our benefits.

I hope that you have also got my personal thoughts for you...

If you have, then Id like to change that, as you would expect.

Im truely hoping that we can continue to increase our interactions together over time and Im sure that you will interpret this in an appropriate manner, as always you know that I have immense respect for you works here, but far more than that you have a special level of sophistication that I can never hope to live up to, but I try to do my best and I am greatful that you are patient with me.

Your resourcefullness is astounding, thank you for the karma.

Stay well and be happy, you are a wonderful person.

cheers

arkay.

Last Edited by arkay on 03/02/2013 08:14 PM

This article heralds some very unsettling news.

While we have all heard the many pros and cons for H5N1 avian influenza research, we have here a clear example of the benefits that some of that research can bring to us, and I do note that this particular research didnt qualify as an approved type by those who would place themselves in a position to judge, which is also worrying.

What we see in this work is a new understanding of H5N1 and just one mutation that it needs that we havent previously been aware of, which would allow it to be carried and vectored by ducks, but of greater serious concern is the fact that this one mutation could make this virus even more contagous to mammals ( humans) and also highten its lethality a further 50%.

If this mutation ever occurs it would be fair to say that it would virtually totally decimate the entire human population from the planet.

Very few if any, would survive.

This is why we need to do research, and what lunatic would ever consider the release of such an uncontrolled bug on humanity to certainly become its victim himself.

Logic people, we need logic.

Study: Single H5N1 mutation confers increased viral growth in mice
A single mutation in the H5N1 avian flu virus that affects the pH at which the hemagglutinin protein is activated also simultaneously reduces its capacity to infect ducks and enhances its capacity to grow in mice, according to a study yesterday in the Journal of Virology. Researchers from St. Jude Children's Hospital in Memphis studied a previously lab-mutated version of the influenza H5N1 virus called K58I that resists acid activation and loses its capacity to infect ducks. Because the upper airways of mammals are more acidic than infected tissues of birds, they hypothesized that the virus may be more infective in mammals. In fact, their study found that K58I grows 100-fold better than wild-type H5N1 in the nasal cavities of mice and is 50% more lethal.

Link here...

[link to www.cidrap.umn.edu]

New sequencing information on the novel coronavirus is revealing this bug to be H2H transmissible and is apparently seperate from bat sequences taken from Europe, Africa and Asia, leaving the reservoir for this unique coronavirus yet to be identified.

New Human Qatar Beta2c Coronavirus Sequence
Recombinomics Commentary 16:00
March 2, 2013


The Wellcome Trust has deposited a full beta2c sequence for the Qatar patient (49M) who has been hospitalized in the UK for the past 5 months. The new sequence, designated Human betacoronavirus 2c England-Qatar/2012, is available at Genbank. It exactly matches England1, which was a direct sequences generated by the Health Protection Agency (HPA) from the clinical sample.

Break...

This high level of identity supports transmission in humans and the human sequences (WGS and partial) are easily distinguished from all prior beta 2c sequences from bats in Europe, Africa, and Asia.

Link here...

[link to www.recombinomics.com]

Wonderful work Arkay.... and all other contributors as well.


Have a pleasant week.

The latest WHO summary for influenza is now available.

Influenza Update Number 180
---------------------------
Summary
-------
- Influenza activity in North America continued to decrease overall, though activity remained high in some areas. The proportion of influenza B increased slightly, but influenza A(H3N2) was still the most commonly detected virus subtype. The season has been more severe than average in the United States of America, with notably high number of pneumonia and influenza-related hospitalizations among adults aged 65 years and older.
- Influenza activity in Europe decreased in some northern and western countries but continued to increase in the eastern part of the region. While influenza A(H1N1)pdm09 was the most commonly detected virus overall, notable exceptions included Denmark, Ireland and the United Kingdom, which reporting much more influenza A(H3N2) and influenza B than the rest of Europe, and Bulgaria, Italy, and Spain which reported more influenza B than A. Excess mortality for the 14 countries reporting to the European Mortality Monitoring project has been higher than average for individuals over the age of 65 years but not as high as the previous 2 seasons.
- Influenza activity throughout the temperate region of Asia decreased except in Mongolia where it appears to have reached a peak.
- Only low levels of influenza activity were reported across the tropical regions of the world and activity in countries of the southern hemisphere remained at inter-seasonal levels.

Link here...

[link to www.promedmail.org]

In the left menu under the heading...

01 Mar 2013 Influenza (23): WHO global update

Vietnam is claiming a major uptick in H5N1 avian influenza with three provinces newly reporting cases.

Add three provinces announced in poultry, cattle
02/03/2013 3:00 02/03/2013 3:00

According to the Department of Animal Health, up to 28.2 there were seven provinces and the outbreak of avian influenza, foot and mouth disease (FMD), blue ear pig disease, less than 21 days.

Biggest outbreak of avian influenza.

Only day 28.2 3 more provinces: Dien Bien, Khanh Hoa and Kien Giang announced bird flu, with 8857 birds infected.

Link here...

[link to www.thanhnien.com.vn]

Thank you for your kind words, on behalf of everyone.

stay well.

arkay and all of us.

Here is a brief summary of this years impact from H1N1 swine flu in India.

A terrible situation and probably the worst globally.


India witnesses 275 deaths from swine flu

Published by: Shobhit Kalra
Published on: Fri, 01 Mar 2013 at 08:28 IST

New Delhi: A total of 275 people across India have succumbed to swine flu this year while over 2,500 others have tested positive for the disease, the health ministry on Friday said.

While Rajasthan recorded the maximum of 112 deaths, Gujarat was second with 58 fatalities. Twelve people have died due to the disease in Delhi.

Link here...

[link to www.pardaphash.com]

Not surprisingly, Indonesia continues to report more H5N1 avian influenza outbreaks.

Forest - Dozens of chickens owned RT 4 RW 2, District Kalinyamat Kulon, District MARGADANA, Tegal in the last three days off dramatically.

Rapid Test results done Department of Agriculture and Marine (Dislatan) positive stop bird flu. Following up on this, together with related state citizens burn the carcasses of dead chickens. Besides spray and provide counseling in the community.

According to the chief of Kasie Kalinyamat Permas Kulon, Ari Wibowo Adfi SH, dozens report dead birds suddenly, was presented Dislatan and followed up.

"Done citizen to get a report, we reported to Dislatan. Revenue Rapid Test turned out positive for bird flu. We hope the community to report it, when there is such an incident," explains Ari, yesterday

Link here...

[link to www.jpnn.com]

google translated.

Here again is a further report af another outbreak of H5N1 in Indonesia.

This article goes on to indicate that some of the Indo authorities appear to be finally getting the message of how quickly and deadly this virus really is.

Perhaps we will witness a more responsible attitude towards the rest of the world for their officials from now on.

It has taken far too long for the message to get through to them.

Chickens Positive Bird Flu

Curup CENTRAL, BE - A total of 5 chickens in RT 11 RW 04 Sub Sidorejo District Central Curup, tested positive for bird flu H5N1 virus. The case came to light after officials Pukeswan Curup do a quick (rapid test) samples of chickens that died suddenly.


Chairman of RT 11 Sukarman to Bengkulu Express, Friday (01/3) explains, the disclosure of positive chicken bird flu began when Kelvin (30) local residents, found some of his village chickens died suddenly. "The death of chickens was held almost every day, and die suddenly was driving was reported to us," said Sukarman.


The case of the mysterious death of chickens were reported to the officer was driving Pukeswan Curup, and sample examination. "Some of the chickens that died was buried and burned so as not to infect other animals. Enclosure that is sprayed disinfectant, "said Chairman of RT.


Bird flu is a contagious animal residents, continued Sukarman, began when the owner of the chicken Kelvin bought two chickens at the market top. "Chicken is suspected to be the origin of the spread of bird flu, a contagious livestock fowl Kelvin," said Chairman of RT.

Link here...

[link to bengkuluekspress.com]

google translated.

[link to mbio.asm.org]


corona virus in cows pigs in mammals

[link to dohanews.co]

Good morning UK anon!

It would appear that we share a common afliction..no?

Last Edited by arkay on 03/03/2013 03:16 PM