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For the First Time, A Wirelessly Controlled Implantable Pharma-Chip Oozes Drugs Into the Body

 
Cat Mouth
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02/17/2012 06:36 AM
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For the First Time, A Wirelessly Controlled Implantable Pharma-Chip Oozes Drugs Into the Body
In the future, implantable computerised dispensaries will replace trips to the pharmacy or doctor's office, automatically leaching drugs into the blood from medical devices embedded in our bodies. These small wireless chips promise to reduce pain and inconvenience, and they'll ensure that patients get exactly the amount of drugs they need, all at the push of a button.

In a new study involving women with osteoporosis, a wirelessly controlled implantable microchip successfully delivered a daily drug regimen, working just as well, if not better, than a daily injection. It could be an elegant solution for countless people on long-term prescription medicines, researchers say. Patients won't have to remember to take their medicine, and doctors will be able to adjust doses with a simple phone call or computer command.

Pharmacies-on-a-chip could someday dispense a whole suite of drugs, at pre-programmed doses and at specific times, said Robert Langer, the Institute Professor at the David H. Koch Institute for Integrative Cancer Research at MIT, who is a co-author on the study.

"It really depends on how potent the drugs are," he said. "There are a number of drugs for things like multiple sclerosis, cancer, and some vaccines that would be potent enough."

Langer and fellow MIT professor Michael Cima developed an early version of an implantable drug-delivery chip in the late 1990s. They co-founded a company called MicroCHIPS Inc., which administered the study being published today in Science Translational Medicine. The team decided to work with osteoporosis patients because the disease, and the drug used to treat it, presented a series of special opportunities, Langer said.

A widely used drug called teriparatide can reverse bone loss in people with severe osteoporosis, but it requires a daily injection to work properly. This means up to 75 per cent of patients give up on the therapy, Langer said. It's also a very potent drug that requires microgram doses, making it an ideal candidate for a long-term dispensary implant.

Getting the chips to work well required some tinkering on the part of the company, including the addition of a hermetic seal and drug-release system that can work in living tissue. The chip contains a cluster of tiny wells, about the size of a pinprick, which store the drug. Each well is sealed with an ultrathin layer of platinum and titanium, Langer said. At programmed times or at the patient's command, an external radio-frequency device sends a signal to the chip, which applies a voltage to the metal film, melting it and releasing the drug. The wells melt one at a time.

"It's like blowing a fuse, the way we've got it set," Langer said. He said the amount of metal is near nanoscale levels and is not toxic.

Pictures and rest of article here [link to www.popsci.com.au]

Last Edited by Cat Mouth on 02/17/2012 06:37 AM
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Anonymous Coward
User ID: 275632
United Kingdom
02/17/2012 06:39 AM
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Re: For the First Time, A Wirelessly Controlled Implantable Pharma-Chip Oozes Drugs Into the Body
dont post this propaganda,this new pill is the filth of satan


stick it up your arse OP
Anonymous Coward
User ID: 10928756
United Kingdom
02/17/2012 06:59 AM
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Re: For the First Time, A Wirelessly Controlled Implantable Pharma-Chip Oozes Drugs Into the Body
dont post this propaganda,this new pill is the filth of satan


stick it up your arse OP
 Quoting: Anonymous Coward 275632


What's your problem dude, do not want people to be aware of what to look out for?
Anonymous Coward
User ID: 275632
United Kingdom
02/17/2012 07:01 AM
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Re: For the First Time, A Wirelessly Controlled Implantable Pharma-Chip Oozes Drugs Into the Body
What's your problem dude, do not want people to be aware of what to look out for?
 Quoting: Anonymous Coward 10928756


the article op posted paints a picture of this new pill being the answer to health problems,the reality is,this pill is the filth of satan

do you have a problem with that ???

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