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On Prescription Meds? The Grapefruit Will Kill You ...

 
Anonymous Coward
User ID: 23660254
United States
11/29/2012 06:07 AM
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On Prescription Meds? The Grapefruit Will Kill You ...
Just a heads up...

Because of new chemical formulations, prescription drugs that interact badly with grapefruit have more than doubled in number since 2008, yet many doctors seem unaware of this.

"The number of drugs on the market with the potential to produce serious adverse and in many cases life-threatening effects when combined with grapefruit has markedly increased over the past few years from 17 to 43 in four years," said lead researcher David Bailey, from the Lawson Health Research Institute in London, Ontario.

Even small amounts of grapefruit or grapefruit juice have the potential to cause sudden death, acute kidney failure, respiratory failure, gastrointestinal bleeding and other serious side effects when paired with these medications. Included are certain cholesterol-lowering medications, blood pressure drugs, cancer treatments and antibiotics such as erythromycin...

[link to healthyliving.msn.com]

pennywise
Anonymous Coward
User ID: 21734520
Finland
11/29/2012 06:11 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
At one stage of my life I was getting high on over the counter codeine-based cough syrups. Grapefruit juice inhibits the enzyme that processes opiates out of your system and I was hoping to use it to boost the effect of codeine. It never worked for me, though.
natasha77
DOOMSEXY

User ID: 28641059
United States
11/29/2012 06:15 AM

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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Wow, thanks for the tip.
SPEAK UP. SILENCE IS DEADLY!

I am currently experiencing life at several WTFs per hour.

DEAL WITH IT. WE ALL HAVE OPINIONS. RESPECT MINE.
Anonymous Coward
User ID: 1110734
United States
11/29/2012 06:19 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Actually grapefruit interferes with cytochrome P450 in the liver. It strengthens some medicine, makes others weaker, has various effects, or zero effect depending upon the medication. It's not grapefruit doom yet.

A wise patient look up drug interactions with the medications they take and compare that with known interactions with foods like grapefruit, or the very common interactions with tobacco or alcohol.
Anonymous Coward
User ID: 5248308
United States
11/29/2012 06:21 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Just a heads up...

Because of new chemical formulations, prescription drugs that interact badly with grapefruit have more than doubled in number since 2008, yet many doctors seem unaware of this.

"The number of drugs on the market with the potential to produce serious adverse and in many cases life-threatening effects when combined with grapefruit has markedly increased over the past few years from 17 to 43 in four years," said lead researcher David Bailey, from the Lawson Health Research Institute in London, Ontario.

Even small amounts of grapefruit or grapefruit juice have the potential to cause sudden death, acute kidney failure, respiratory failure, gastrointestinal bleeding and other serious side effects when paired with these medications. Included are certain cholesterol-lowering medications, blood pressure drugs, cancer treatments and antibiotics such as erythromycin...

[link to healthyliving.msn.com]

pennywise
 Quoting: exiled1


bsflag from Big Pharma which would have you dependent and requiring to purchase ever more drugs.

Quercetin will supercharge your meds so you do not need take so much/many. Save money.
Anonymous Coward
User ID: 1028241
Canada
11/29/2012 06:26 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Get rid of the pill and eat Grapefruit.
Anonymous Coward (OP)
User ID: 23660254
United States
11/29/2012 06:27 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Just a heads up...

Because of new chemical formulations, prescription drugs that interact badly with grapefruit have more than doubled in number since 2008, yet many doctors seem unaware of this.

"The number of drugs on the market with the potential to produce serious adverse and in many cases life-threatening effects when combined with grapefruit has markedly increased over the past few years from 17 to 43 in four years," said lead researcher David Bailey, from the Lawson Health Research Institute in London, Ontario.

Even small amounts of grapefruit or grapefruit juice have the potential to cause sudden death, acute kidney failure, respiratory failure, gastrointestinal bleeding and other serious side effects when paired with these medications. Included are certain cholesterol-lowering medications, blood pressure drugs, cancer treatments and antibiotics such as erythromycin...

[link to healthyliving.msn.com]

pennywise
 Quoting: exiled1


bsflag from Big Pharma which would have you dependent and requiring to purchase ever more drugs.

Quercetin will supercharge your meds so you do not need take so much/many. Save money.
 Quoting: Anonymous Coward 5248308


thats just stupid(BS flag), and beside the point. The thread is just here to make people aware.
If one is on these medications and doesn't realize the possible consequences...well, it is always better to know.
Anonymous Coward
User ID: 230720
Germany
11/29/2012 07:07 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good post for making people aware as I don't know what the communication about this has been like in the States.
Over here though it's been advertised in every medical centre for a few years.
Anonymous Coward
User ID: 9014106
Australia
11/29/2012 07:13 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good to know.

On the other hand, the Prescription Meds on their own may kill you too.
Anonymous Coward (OP)
User ID: 23660254
United States
11/29/2012 07:13 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good post for making people aware as I don't know what the communication about this has been like in the States.
Over here though it's been advertised in every medical centre for a few years.
 Quoting: Anonymous Coward 230720


I, personally, am not on any medication, but do realize many are...I have never heard of it, the possible interactions, story states many American Doctors seem unaware, so I decided to post...thanks
Anonymous Coward
User ID: 1378669
United States
11/29/2012 07:15 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
All the opiate abusers know about this. Everyone that pops pills drinks grapefruit juice all day. The high is way better they say.
Anonymous Coward
User ID: 1110734
United States
11/29/2012 07:16 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good post for making people aware as I don't know what the communication about this has been like in the States.
Over here though it's been advertised in every medical centre for a few years.
 Quoting: Anonymous Coward 230720


I, personally, am not on any medication, but do realize many are...I have never heard of it, the possible interactions, story states many American Doctors seem unaware, so I decided to post...thanks
 Quoting: exiled1

The information is in a standard Physician's Desk Reference (PDR) about drug interactions with grapefruit. No one can make a person open the book and read it.
Anonymous Coward (OP)
User ID: 23660254
United States
11/29/2012 07:22 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good post for making people aware as I don't know what the communication about this has been like in the States.
Over here though it's been advertised in every medical centre for a few years.
 Quoting: Anonymous Coward 230720


I, personally, am not on any medication, but do realize many are...I have never heard of it, the possible interactions, story states many American Doctors seem unaware, so I decided to post...thanks
 Quoting: exiled1

The information is in a standard Physician's Desk Reference (PDR) about drug interactions with grapefruit. No one can make a person open the book and read it.
 Quoting: Anonymous Coward 1110734


but if someone happens to be reading over threads here, they might just see this...not everyone has an up to date 'PDR' handy, you know.
Anonymous Coward
User ID: 1110734
United States
11/29/2012 08:19 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Good post for making people aware as I don't know what the communication about this has been like in the States.
Over here though it's been advertised in every medical centre for a few years.
 Quoting: Anonymous Coward 230720


I, personally, am not on any medication, but do realize many are...I have never heard of it, the possible interactions, story states many American Doctors seem unaware, so I decided to post...thanks
 Quoting: exiled1

The information is in a standard Physician's Desk Reference (PDR) about drug interactions with grapefruit. No one can make a person open the book and read it.
 Quoting: Anonymous Coward 1110734


but if someone happens to be reading over threads here, they might just see this...not everyone has an up to date 'PDR' handy, you know.
 Quoting: exiled1


My meaning is that it's considered part of a physician's responsibility to know about any potential issues with drugs and common interactions. Much of the drudgery of combing through a PDR has been eliminated by scanning for search terms electronically.They should warn you, but given that you might spend all of 8 actually minutes actually consulting a doc, then what you can expect them to pass along with such brevity?

Most patiens have inserts in their medications when they take samples, but probably don't read them. The data is on that too generally.

There's been drug interactions with grapefruit before with things like Seldane back in 2001. Actually if we understood the complex biochemistry of graprefruit better, then in some cases we probably could enhance some drugs by combining it synergistically, and probably lower the cost.

For example, caffeine potentiates many drugs, and it's an additive in certain medications. However, I bet that no one has ever told you not to drink coffee with your meds, because people don't think of that particular drug interaction. Other common things like niacin or tobacco increase blood circulation to the brain, and could alter the effect a drug has as a result.

There are many websites now that allow a patient to type in all their medications to see if there's any potential drug interactions between them. Not only that, but you can also pull up the PDR type information in an informal way to see if common substances interact as well.
[link to www.drugs.com]

Sometimes an herbal drug can interact too, so people who use them, should really see if this can happen based upon the medicines and herbs they take. Let's say someone was on Prozac (Fluoxetine) for depression. Then they also took St. John's Wort too from time to time. Both have a similar mechanism of action to be selective serotonin reuptake inhibitors. This makes serotonin hang around longer in the brain so people feel happier. You could actually be way magnifying the effects by double dosing like that, which could cause Serotonin Shock Syndrome.

I'm not anti-herbs either. I've talked about them regularly here, but people should realize their power. Likewise food can be a potent magnifier of medicines.
Anonymous Coward
User ID: 27999563
United States
11/29/2012 09:33 AM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Actually grapefruit interferes with cytochrome P450 in the liver. It strengthens some medicine, makes others weaker, has various effects, or zero effect depending upon the medication. It's not grapefruit doom yet.

A wise patient look up drug interactions with the medications they take and compare that with known interactions with foods like grapefruit, or the very common interactions with tobacco or alcohol.
 Quoting: Anonymous Coward 1110734


I smoke cigarettes. How do I find out what drugs tobacco effects?

Please advise.
Anonymous Coward (OP)
User ID: 23660254
United States
11/29/2012 01:21 PM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
...


I, personally, am not on any medication, but do realize many are...I have never heard of it, the possible interactions, story states many American Doctors seem unaware, so I decided to post...thanks
 Quoting: exiled1

The information is in a standard Physician's Desk Reference (PDR) about drug interactions with grapefruit. No one can make a person open the book and read it.
 Quoting: Anonymous Coward 1110734


but if someone happens to be reading over threads here, they might just see this...not everyone has an up to date 'PDR' handy, you know.
 Quoting: exiled1


My meaning is that it's considered part of a physician's responsibility to know about any potential issues with drugs and common interactions. Much of the drudgery of combing through a PDR has been eliminated by scanning for search terms electronically.They should warn you, but given that you might spend all of 8 actually minutes actually consulting a doc, then what you can expect them to pass along with such brevity?

Most patiens have inserts in their medications when they take samples, but probably don't read them. The data is on that too generally.

There's been drug interactions with grapefruit before with things like Seldane back in 2001. Actually if we understood the complex biochemistry of graprefruit better, then in some cases we probably could enhance some drugs by combining it synergistically, and probably lower the cost.

For example, caffeine potentiates many drugs, and it's an additive in certain medications. However, I bet that no one has ever told you not to drink coffee with your meds, because people don't think of that particular drug interaction. Other common things like niacin or tobacco increase blood circulation to the brain, and could alter the effect a drug has as a result.

There are many websites now that allow a patient to type in all their medications to see if there's any potential drug interactions between them. Not only that, but you can also pull up the PDR type information in an informal way to see if common substances interact as well.
[link to www.drugs.com]

Sometimes an herbal drug can interact too, so people who use them, should really see if this can happen based upon the medicines and herbs they take. Let's say someone was on Prozac (Fluoxetine) for depression. Then they also took St. John's Wort too from time to time. Both have a similar mechanism of action to be selective serotonin reuptake inhibitors. This makes serotonin hang around longer in the brain so people feel happier. You could actually be way magnifying the effects by double dosing like that, which could cause Serotonin Shock Syndrome.

I'm not anti-herbs either. I've talked about them regularly here, but people should realize their power. Likewise food can be a potent magnifier of medicines.
 Quoting: Anonymous Coward 1110734


All very good points. There are many things people ingest without a second thought. The info on the PDR will help many. Thanks
Anonymous Coward (OP)
User ID: 23660254
United States
11/29/2012 01:25 PM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
Actually grapefruit interferes with cytochrome P450 in the liver. It strengthens some medicine, makes others weaker, has various effects, or zero effect depending upon the medication. It's not grapefruit doom yet.

A wise patient look up drug interactions with the medications they take and compare that with known interactions with foods like grapefruit, or the very common interactions with tobacco or alcohol.
 Quoting: Anonymous Coward 1110734


I smoke cigarettes. How do I find out what drugs tobacco effects?

Please advise.
 Quoting: Anonymous Coward 27999563


Perhaps try this link someone else put up here: [link to www.drugs.com]

-or maybe, the know-it-all dbag who gave me red karma for this thread can enlighten us...peace
GeordieLegend

User ID: 4912635
Netherlands
11/29/2012 01:26 PM
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Re: On Prescription Meds? The Grapefruit Will Kill You ...
...is there anything left that isnt killing us..?
Propaganda has to be popular and has to accommodate itself to the comprehension of the least intelligent of those whom it seeks to reach...