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Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?

 
freedomain
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User ID: 23423659
United Kingdom
11/30/2012 08:52 PM

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Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?
An acellular whooping cough vaccine actually enhances the colonization of Bordetella parapertussis in mice; pointing towards a rise in B. parapertussis incidence resulting from acellular vaccination, which may have contributed to the observed increase in whooping cough over the last decade.
vaccination led to a 40-fold enhancement of B. parapertussis colonization in the lungs of mice
Despite this vaccine being hugely effective against B. pertussis, which was once the primary childhood killer, these data suggest that the vaccine may be contributing to the observed rise in whooping cough incidence over the last decade by promoting B. parapertussis infection.
[link to www.cidd.psu.edu]


Bordetella pertussis and Bordetella parapertussis:
Two Immunologically Distinct Species -
Bordetella pertussis and BordeteUla parapertussis are closely related species. Both are responsible for
outbreaks of whooping cough in humans and produce similar virulence factors,
'As expected, pertussis toxin did not protect against B. parapertussis infection, since this bacterium did not
express this protein, but the surprising result was that none of the other factors were protective against B.
parapertussis infection.'
[link to iai.asm.org]
freedomain (OP)

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11/30/2012 09:31 PM

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Re: Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?
more info -
[link to www.nvic.org]
Anonymous Coward
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12/01/2012 03:32 AM
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Re: Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?
bump
freedomain (OP)

User ID: 23423659
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12/05/2012 05:40 PM

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Re: Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?
bump
for more to see
freedomain (OP)

User ID: 23423659
United Kingdom
12/09/2012 06:54 PM

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Re: Whooping Cough Outbreaks caused by Vaccine ? - 2 Whooping Cough Diseases ?
An acellular whooping cough vaccine actually enhances the colonization of Bordetella parapertussis in mice; pointing towards a rise in B. parapertussis incidence resulting from acellular vaccination, which may have contributed to the observed increase in whooping cough over the last decade.
vaccination led to a 40-fold enhancement of B. parapertussis colonization in the lungs of mice
Despite this vaccine being hugely effective against B. pertussis, which was once the primary childhood killer, these data suggest that the vaccine may be contributing to the observed rise in whooping cough incidence over the last decade by promoting B. parapertussis infection.
[link to www.cidd.psu.edu]


Bordetella pertussis and Bordetella parapertussis:
Two Immunologically Distinct Species -
Bordetella pertussis and BordeteUla parapertussis are closely related species. Both are responsible for
outbreaks of whooping cough in humans and produce similar virulence factors,
'As expected, pertussis toxin did not protect against B. parapertussis infection, since this bacterium did not
express this protein, but the surprising result was that none of the other factors were protective against B.
parapertussis infection.'
[link to iai.asm.org]
 Quoting: freedomain

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