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Heart risk link to SSRI antidepressants confirmed

 
phocuss

User ID: 783356
United States
01/30/2013 01:00 PM

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Heart risk link to SSRI antidepressants confirmed
Some but not all antidepressant drugs known as SSRIs pose a very small but serious heart risk, say researchers.

Citalopram and escitalopram, which fall into this drug group, can trigger a heart rhythm disturbance, a new study in the British Medical Journal shows.

UK and US regulators have already warned doctors to be extra careful about which patients they prescribe these medicines to.

And they have lowered the maximum recommended dose.

The UK's Medicines and Healthcare products Regulatory Agency (MHRA) says people with pre-existing heart conditions should have a heart trace before going on these drugs, to check for a rhythm disturbance known as long QT interval.

Experts reassure that complications are very rare and that in most cases the benefits for the patient taking the drug will outweigh the risks.

Read more: [link to www.bbc.co.uk]
Anonymous Coward
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01/30/2013 01:19 PM
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Re: Heart risk link to SSRI antidepressants confirmed
i am withdrawing from citalapram as of last monday....fuck the heart problems

once youre on its freakin horrible to get off!!!!!!!!
^Faceless^

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01/30/2013 01:25 PM
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Re: Heart risk link to SSRI antidepressants confirmed
Absolutely. That's why we have to ban guns and marijuana.

-Your public servents
^Faceless^

User ID: 9581681
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01/30/2013 01:25 PM
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Re: Heart risk link to SSRI antidepressants confirmed
Absolutely. That's why we have to ban guns and marijuana.

-Your public servents
 Quoting: ^Faceless^


Whoops should be public serpents (typo).
Anonymous Coward
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01/30/2013 01:26 PM
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Re: Heart risk link to SSRI antidepressants confirmed
bump
phocuss (OP)

User ID: 783356
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01/30/2013 01:28 PM

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Re: Heart risk link to SSRI antidepressants confirmed
Medical marijuana reduces chronic pharmaceutical use - [link to www.naturalnews.com]
Anonymous Coward
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02/11/2013 04:06 AM
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Re: Heart risk link to SSRI antidepressants confirmed
The musician below died not from some massive overdose of his tricyclic antidepressant, but from one additional tablet.
According to his parents he thought he had forgotten a dose.

Researchers thought SSRIs were going to be safer:

[link to www.theheart.org]

Findings from a prospective cohort study suggest tricyclic antidepressants (TCAs) are associated with a 35% increased risk of cardiovascular disease (CVD), which is not explained by existing psychiatric illness [1].


They were wrong:

[link to www.bbc.co.uk]

If SSRIs kill people with Long QT, combining medications may be dangerous, because Long QT may be induced:

[link to www.nhlbi.nih.gov]

Medication-Induced Long QT Syndrome

More than 50 medicines have been found to cause LQTS. Some common medicines that may cause the disorder include:
•Antihistamines and decongestants
•Diuretics (pills that remove excess water from your body)
•Antibiotics
•Antiarrhythmic medicines
•Antidepressant and antipsychotic medicines
•Cholesterol-lowering medicines and some diabetes medicines

Some people who have medication-induced LQTS also may have an inherited form of the disorder. They may not have symptoms unless they take medicines that lengthen the QT interval or lower potassium levels in the blood. When LQTS doesn't cause symptoms, it's called silent LQTS.




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