Parkinson's Disease...is there a holistic cure?

ah

there do seem to be

natural dopamine agonists

acetyl l carnitine comes to mind
and does nadh
and does mucuna puriens

none of these adds up to a cure
but might be mildly
pallitive

the fact the tobacco smokers have
statistically
a lesser rate of parkinsons
is certainly intriquing

what in the tobacco smoke is
neuroprotective

how do we keep
the substania nigra from
self destructing
and can we repair the damage
after its been done

i just dont see why not
why not
indeed


peace

this is the poster who posted about there being no natural treatment for parkinsons,


yes it true smoking prevents parkinsons but theres 70% of the population who doesnt smoke and some of them get parkinsons. theres also a handful of smokers who get parkinsons. the mechanism by which smoking prevents parkinsons cannot be explained to you because you arent smart enough to comprehend it.

anyway, getting back to the topic,

like i said, there is no natural treatment for parkinsons.

Im sorry if you have an emotional attachment to naturals, but there is no natural treatment for parkinsons. the person has to take dopamine agonists. to get cured, the person has to wait until high technology totally regenerates dopamine cells, such as future stem cell technology

WRONG none of those are dopamine agonists, and one is simply a plant that contains L-Dopa WITHOUT C-dopa plus like 100 other active alkaloids that produce side effects

the person is much better of with L-dopa in a pill that contains C-dopa too. Mucuna does not contain C-dopa, plus contains a shit load of other things that cause side effects.

god your fucking dumb

20-40 -

WRONG you stupid uneducated son of a bitch

first off, nicotine patches have NOTHING to do with parkinsons

it is another compound in tobacco, not nicotine, that is the MAO-B inhibitor and protective agent

secondly, everything else you listed is bullshit

your fucking dumb as shit

I'm sorry but your selfish hypothesis can be easily challenged and proven wrong. it's unusual that you arent able to realize that alternative.

the people here are so god damn stupid, that they think its nicotine and say "dont stop nicotine patches" (scroll up and see that guys post)

nicotine has nothing to do with protection from parkinsons. it is not nicotine that is MAOB inhibitor and nitric oxide inhibitor, it is OTHER COMPOUNDS in tobacco

the other things you listed wont work, because even THE MOST POWERFUL PHENETHYLAMINE and ERGOT dopamine agonists have trouble working

if even the most powerful dopamine agonists that resemble dopamine work, how is a vitamin going to work

youre a fucking moron, like all the other uneducated trash here that constantly posts BULLSHIT on a daily fucking basis .

Yeah, you're right. I must be a fucking moron like all the other "uneducated" people posting messages into this thread. although you should reconsider that your the one posting the bullshit. but lets put the subject of parkinson's disease aside for now and focus on your problems instead...

Why do you assume that everyone here is "trash"? is it because you believe they're copying and pasting misinformation from corrupt sources, that have no credibility or helped anybody's condition?

Are you just trying to defend your convetional belief system, trying your best to debunk the possibility that holistic/alternative methods provide a helpful solution?

this guy suggested nicotine patches to non-smokers

that would make a non smoker sick as fuck, have intense nightmeres, and do nothing for parkinsons, as it is not nicotine, but other compounds in tobacco that are the protective agents. and after you have parkinsons, the protective agents are no good, they might extend your lifespan by 3 weeks or so

thats how dumb the people are here. they have no idea what they are talking about and just guess things. for instance if they read smoking is protective against Parkinson's, their shit-brain will automatically conclude nicotine is a treatment when in actuality its not the nicotine thats responsible

this is just one example of how the people at GLP are unable to function, mind-wise.

now im going to sign off forever. bye

Hey, asshole,

the people here all post contradictions and nonsense

im sorry but thats the truth, read the post right before this one for ONE example out of THOUSANDS

the post above is a perfect example of exactly what its like for THOUSANDS AND THOUSANDS of posts

do you understand?

The following is ONE Example out of THOUSANDS of instances of GLP Logic

I cannot say how sorry I am 'cause I've posted here.

The following is ONE example out of THOUSANDS of instances of GLP style logic:

1) User reads about how tobacco is preventative against Parkinson's

2) User remembers that nicotine is the stuff in tobacco, so he posts on Parkinson's threads for people to use Nicotine patches for Parkinson's

3) But the truth is, actually Nicotine is NOT the compound in tobacco that is preventative, its ANOTHER compound in tobacco that is responsible. also being preventative and slowing down progressive of already existent diseases are two seperate things

4) those the user posts dis-information on GLP, and in this particular case, if someone tries it, they vomit a bunch of times and have nightmeres.

The above is ONE perfect example of the process that goes on in THOUSANDS of threads because of stupidity, degenerate brains


a quick second example, if a second is needed, would be the GLP users who recommend antibiotics (bacteria killers) for illness that are caused by VIRUSES and NOT BACTERIA. this shit isnt even funny anymore

Although you do have an interesting point,


You are pretty much....

look up "pesticides" "Parkinsons", aspartame is just not good at all...avoid, and do not use insect spray in the home especially Baygon (surface spray)and move away from agricultural areas where aerial spraying occurs or where the water is contaminated with pesticides...detoxing may help...

What the HELL is wrong with this board? This abusive motherfucker talking about how STUPID everyone else is.....and he's TOTALLY WRONG.

Journal Article
Psychopharmacology

Nicotine may relieve symptoms of Parkinson's disease
Journal Psychopharmacology
Publisher Springer Berlin / Heidelberg
ISSN 0033-3158 (Print) 1432-2072 (Online)
Subject Biomedical and Life Sciences and Medicine
Issue Volume 116, Number 1 / September, 1994
Category Rapid Communications
DOI 10.1007/BF02244882
Pages 117-119
Online Date Wednesday, November 16, 2005

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Rapid Communications
Nicotine may relieve symptoms of Parkinson's disease

Karl Olov Fagerström1 Contact Information, Ovide Pomerleau2, Bruno Giordani2 and Fred Stelson2
(1) Pharmacia Research Laboratories, Box 941, S-251 09 Helsingborg, Sweden
(2) Medical Center, University of Michigan, 48108 Ann Arbor, Michigan, USA

Received: 6 May 1994 Accepted: 10 May 1994
Abstract Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated with active nicotine dosing and involved diminished tremor and disorganized thinking in one patient and diminished bradykinesia and increased energy in the other.

Key words Parkinson's disease - Treatment - Nicotine patch - Nicotine gum



GOOGLE IT ASSHOLE, there are thousands of articles on the web, mainstream media that NICOTINE, NOT COMPONENTS in smoke is what is being explored to help Parkinson's.


FREAK.

No, you dont understand.

nicotine only relieves it a little because it causes the release of dopamine

but at the same time IT IS NOT THE AGENT IN TOBACCO THAT PREVENTS PARKINSON'S, THATS A DIFFERENT AGENT, AN MAO-B INHIBITOR

also dopamine release doesnt stop the death of dopamine neurons - it just makes the ones dying release more dopamine for a while, then die, then you die.

i kinda liked that ac

he was so cocksure of his own misconceptions
so right
so goddamm right

probably about
everything

yepper

mcubik liked him

so goddamm right
and then he ran off


peace

perhaps mr angry has had a bit too much
crank in his day
destroyed his substansia nigra
and now is
well
permanently
cranky


anyway op

google the life extension foundation

they are pretty much up on

nutritional
herbal
and
pharmalogical

support
for numerous ailments

parkinsons is in their book
i know

good good luck
and
peace

I know a little about Parkinson's disease. Even top neurologists don't know for sure what the cause is, but what I know is from living with my husband who has had it for 17 years, and from his father, who died of it in 1985. It is a progressive neurological disease, which causes, or is caused from the center part of the brain, the substancia nigra, to die off. That part of the brain is what makes dopamine, and as it dies off, it makes less and less dopamine, so they have to take L-dopa and other drugs to make a synthetic dopamine.

It a a progressive disease, and it takes of many symptoms, not always the same in every patient. Like, my husband is not a candidate for the brain stimulation operation that works for some. His hands don't shake, but he is very rigid, and has more the dyskenesia that Michael J Fox has. Lots of weakness on his right side, too. He will be walking, and all of a sudden, his feet quit moving, like they are glued to the floor.

I know it will be too late for him, but I do hope they find a cure for it soon, so others don't have to go through what he is going through.

In his earlier part of the disease, he was in several tests with UCSD, where they were testing new drugs. One was a disaster, because the drug didn't work, and was found to cause heart attacks.

I understand that there was good reasons for the posters on here to believe that nicotine itself, not one of the other 4000 chemicals within cigarette smoke was a key component to treating Parkinson's, because that is what the latest scientific data is suggesting. Never have I read anything related to "cigarette smoking", only NICOTINE. So perhaps you blow hards could provide links to these people, instead of insulting them in a barrage of ridiculous ephetats.

Not you personally, DDS.....the other guy.

studies show that nicotine is NOT the component of tobacco that inhibits monoamine oxidase B

look it up

BTW , what a coincidence, selegiline, the drug that slows down the progression of parkinsons, extends general lifespan in rats, and acts as a powerful neuroprotective agent is guess what.......... an MAO-B inhibitor

so lets break it down

1) MAO-B inhibitors are known to be what is protective (look at selegiline)

2) smokers have 40% less MAO-B in their bodies

3) people who use patches and nicotine gum return to normal MAO-B levels after quiting smoking, when they smoked they had less MAO-B

logical conclusion, its other stuff in tobacco that inhibits MAO-B, not nicotine, nicotine doesnt even inhibit it in vitro tests. its something else, like the beta-carbolines in tobacco.

point 2: yes nicotine will temporarily help parkinson's a tiny bit, thats because nicotine causes the release of dopamine (and why its a pleasurable buzz) , however its not the neuroportective agent that prevents parkinsons .

i.e. if you took 10000 people who smoked all their life and 10000 people who used nicotine gum all their life, its a sound prediction that you WILL find the nicotine gum group to have equal parkinson's cases to everyone else, but not the smoking group.

fuckin idiot

[link to whyfiles.org]

If you want to increase the level of a chemical inside the body, you could make more of the chemical. Or you could interfere with the body's mechanism for destroying it.

Recent information concerning dopamine, a neurotransmitter associated with pleasure and well-being, indicates that cigarette smoke might use both techniques for raising dopamine levels. If true, it could have serious consequences for smoking cessation programs.

Nicotine has long been known to stimulate the release of dopamine. Now, research by scientists at Brookhaven National Laboratory (BNL) in New York points toward -- but does not prove -- another mechanism for cigarette addiction. They've found something in cigarette smoke that seems to be slowing the breakdown of dopamine.

brain scans
These brain slices show levels of the "killjoy" enzyme MAO B in the brains of two people. The non-smoker at the top has plenty of MAO B, but the smoker at bottom has much less -- a sign that something in cigarette smoke is destroying MAO B, allowing the pleasure chemical dopamine to tell the body it likes smoking and wants to continue. The Brookhaven researchers believe it's not just nicotine that is sustaining the addiction, but another agent as well. These scans were made with positron emission tomography, which captures the signal from a short-lived radioactive tracer to make color images of brain activity. Courtesy Brookhaven National Lab Center for Imaging and Neurosciences.

The researchers tracked MAO B, an enzyme that breaks down dopamine in the brain. In general, after they are released and transmit their signal, excess dopamine and other neurotransmitters are broken down, or are taken back up and stored in the neuron. If they remain free, they send spurious signals.

FYI, MAO B = ?

If cigarettes are indeed slowing the breakdown of dopamine, it could add up to a one-two punch, says chemist Joanna Fowler of BNL. "Nicotine is known to elevate brain dopamine. But the markedly lower MAO B in the smokers' brains suggests that whatever is inhibiting MAO B could actually be acting in concert with nicotine to enhance dopamine's activity."

The research is preliminary, and it's not clear that the 40 percent reduction in MAO B actually does increase dopamine levels, Fowler stresses. "It's not a real leap that it could enhance dopamine, but we don't know if this really translates into an enhancement in the smoker's body."

Who dun it?
One of the key unknowns is which chemical, among the 4,000 or so identified in cigarette smoke, might be causing the reaction. Fowler says it's not nicotine, based on earlier studies that showed nicotine did not influence MAO B. The difficulty of finding the suspect is not just due to the sheer number of compounds in smoke. If the chemical binds irreversibly to a receptor on brain cells, "it could be something present in minuscule quantities that builds up over years of smoking." Something like that would be extremely difficult to isolate, she says.

The Brookhaven project arose by serendipity (that's scientese for "good luck"), Fowler says, while the research group was studying aging. When neurons (defined) shrink, there's an expansion of glial cells (defined). Since glial cells contain a lot of MAO B , the researchers decided to make images of MAO B levels as a way to track them.

Curiously, they noticed that some subjects had 40 percent less MAO B than others. On investigation, it turned out that what distinguished the low-MAO B group was a history of smoking.

If smokers indeed have an elevated level of brain dopamine, it could have implications for smoking cessation, Fowler speculates. With more dopamine, they might be happier, more content, and bound to their habit by a mechanism that involves the MAO B inhibitor substance as well as nicotine. So just as cigarette quitters sometimes receive nicotine replacement therapy, "it may make sense to give MAO B inhibitors" to lessen the shock of drug withdrawal, Fowler says.

Any practical impact of these discoveries is in the future, but the backdrop for this work is the creation of legions of new smokers. Every day, thousands of young people start to smoke.

Tho I may get flamed like crazy...Smoking or eating dope may help his symptoms and slow degeneration.
THC is known to help with th symptoms and in high doses has shown regeneration of brain tissue.
Look it up before you insult.