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Functioning of aged brains and muscles in mice made younger

 
Uncle Fuck Stick
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05/04/2014 10:26 PM

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Functioning of aged brains and muscles in mice made younger
[link to m.medicalxpress.com]
Harvard Stem Cell Institute (HSCI) researchers have shown that a protein they previously demonstrated can make the failing hearts in aging mice appear more like those of young health mice, similarly improves brain and skeletal muscle function in aging mice.
In two separate papers given early online release today by the journal Science – which is publishing the papers this coming Friday, Professors Amy Wagers and Lee Rubin, of Harvard's Department of Stem Cell and Regenerative Biology (HSCRB), report that injections of a protein known as GDF11, which is found in humans as well as mice, improved the exercise capability of mice equivalent in age to that of about a 70-year-old human, and also improved the function of the olfactory region of the brains of the older mice – they could detect smell as younger mice do.
Rubin and Wagers each said that, baring unexpected developments, they expect to have GDF11 in initial human clinical trials within three to five years. Postdoctoral fellow Lida Katsimpardi is the lead author on the Rubin group's paper, and postdocs Manisha Sinha and Young Jang are the lead authors on the paper from the Wagers group.

Both studies examined the effect of GDF11 in two ways. First, by using what is called a parabiotic system, in which two mice are surgically joined and the blood of the younger mouse circulates through the older mouse. And second, by injecting the older mice with GDF11, which in an earlier study by Wagers and Richard Lee, of Brigham and Women's Hospital who is also an author on the two papers released today, was shown to be sufficient to reverse characteristics of aging in the heart.

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05/04/2014 10:36 PM

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Re: Functioning of aged brains and muscles in mice made younger
Thread: 'Vampire therapy' could reverse aging, scientists find... WTF??? Young Blood May Hold Key to Reversing Aging
Reality Is an Illusion of Separation
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Pooch

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05/04/2014 10:38 PM

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Re: Functioning of aged brains and muscles in mice made younger
yoda
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Uncle Fuck Stick (OP)
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05/04/2014 10:44 PM

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Re: Functioning of aged brains and muscles in mice made younger


Thread: Blood of young mice boosts brains, muscles of older ones - I knew the Elites are Blood Drinkers!!!

ahhh Kermit
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05/04/2014 10:46 PM
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Re: Functioning of aged brains and muscles in mice made younger
[link to m.medicalxpress.com]
Harvard Stem Cell Institute (HSCI) researchers have shown that a protein they previously demonstrated can make the failing hearts in aging mice appear more like those of young health mice, similarly improves brain and skeletal muscle function in aging mice.
In two separate papers given early online release today by the journal Science – which is publishing the papers this coming Friday, Professors Amy Wagers and Lee Rubin, of Harvard's Department of Stem Cell and Regenerative Biology (HSCRB), report that injections of a protein known as GDF11, which is found in humans as well as mice, improved the exercise capability of mice equivalent in age to that of about a 70-year-old human, and also improved the function of the olfactory region of the brains of the older mice – they could detect smell as younger mice do.
Rubin and Wagers each said that, baring unexpected developments, they expect to have GDF11 in initial human clinical trials within three to five years. Postdoctoral fellow Lida Katsimpardi is the lead author on the Rubin group's paper, and postdocs Manisha Sinha and Young Jang are the lead authors on the paper from the Wagers group.

Both studies examined the effect of GDF11 in two ways. First, by using what is called a parabiotic system, in which two mice are surgically joined and the blood of the younger mouse circulates through the older mouse. And second, by injecting the older mice with GDF11, which in an earlier study by Wagers and Richard Lee, of Brigham and Women's Hospital who is also an author on the two papers released today, was shown to be sufficient to reverse characteristics of aging in the heart.

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 Quoting: Uncle Fuck Stick


I want some I want some I want some.
MONSTER

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05/04/2014 11:18 PM

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Re: Functioning of aged brains and muscles in mice made younger


I know where this is headed, I bet these old rich guys are draining young people already.
KINGDOMS, NATIONS AND KINGS HAVE BEEN BROUGHT DOWN TO THEIR KNEES WITH ONE GLANCE FROM A WOMAN.

I WEAR MY SKIN OF ARMOR SO NO ONE CAN GET IN AND NO ONE CAN GET OUT.

HOW CAN I MOURN YOU, WHEN I HAVE NEVER LET YOU GO, monster 1991-2008 RIP
Anonymous Coward
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05/05/2014 12:14 AM
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Re: Functioning of aged brains and muscles in mice made younger


I know where this is headed, I bet these old rich guys are draining young people already.
 Quoting: MONSTER


/SleepingVillage/

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05/05/2014 01:51 AM
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Re: Functioning of aged brains and muscles in mice made younger
Pooch

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05/05/2014 01:58 AM

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Re: Functioning of aged brains and muscles in mice made younger
ahhh.....fuck this shit I can't even think.I'm gonna borrow a tampon and plug the fucking ears....ring a ling.
I don't care what they say about you,I think you are alright.
Anonymous Coward
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05/05/2014 02:08 AM
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Re: Functioning of aged brains and muscles in mice made younger
illuminati knew this all the times

thats why they love drinking baby blood
Anonymous Coward
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05/05/2014 02:10 AM
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Re: Functioning of aged brains and muscles in mice made younger
If this were confirmed as an age reversal treatment that worked well enough to be worth the hassle, it would be not too long before “urban youths” that seem prone to violence, crime, and are unable to be educated, cannot hold a job, and do not contribute to society - it would not be long before laws were restructured to allow the involuntary tapping of their blood on a weekly basis and then using that blood to reverse aging in those elites who are considered productive members of society. While some would obey a court order to show up and be tapped on a weekly basis, others would have to be incarcerated to do so. Also the issue of keeping them off drugs and HIV negative would be a major concern, too. Probably those known to be promiscuous, homosexual, or a drug user would be incarcerated for the duration of their sentence. By consenting to being bled on a weekly basis, they would get time off their initial sentence and be paid a stipend for their service to humanity durng their time in the facility. It would be a small matter, once they were in patient to prescribe various drugs to make them much less prone to violent behavior and/or correct other negative behavior traits as well.

After generations of being labeled (and accurately so) as “good for nothing” at least their blood might prove good for keeping the more productive members of our society healthy and young for a much longer period of time than would otherwise be possible.
/SleepingVillage/

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05/05/2014 02:23 AM
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Re: Functioning of aged brains and muscles in mice made younger
If this were confirmed as an age reversal treatment that worked well enough to be worth the hassle, it would be not too long before “urban youths” that seem prone to violence, crime, and are unable to be educated, cannot hold a job, and do not contribute to society - it would not be long before laws were restructured to allow the involuntary tapping of their blood on a weekly basis and then using that blood to reverse aging in those elites who are considered productive members of society. While some would obey a court order to show up and be tapped on a weekly basis, others would have to be incarcerated to do so. Also the issue of keeping them off drugs and HIV negative would be a major concern, too. Probably those known to be promiscuous, homosexual, or a drug user would be incarcerated for the duration of their sentence. By consenting to being bled on a weekly basis, they would get time off their initial sentence and be paid a stipend for their service to humanity durng their time in the facility. It would be a small matter, once they were in patient to prescribe various drugs to make them much less prone to violent behavior and/or correct other negative behavior traits as well.

After generations of being labeled (and accurately so) as “good for nothing” at least their blood might prove good for keeping the more productive members of our society healthy and young for a much longer period of time than would otherwise be possible.
 Quoting: Anonymous Coward 3063399



Yeah, we could all (or at least some of us) have a little (sedated) degenerate clinger joined to us while we walk around doing elite and productive shit...


/




Let's just slow their breeding and then GM the straglers into compliance...
Anonymous Coward
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05/05/2014 04:20 AM
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Re: Functioning of aged brains and muscles in mice made younger
Aging, at least at the extremely quick rate at which we do it, is just another part of the matrix in which we live.
Goofy for God
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05/05/2014 07:15 AM

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Re: Functioning of aged brains and muscles in mice made younger
Last night on 60 minutes loved it

Before you give up wine and dessert . . .


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