This Simple Test May Help Diagnose Cytokine Storm Early On, Remember The Name If You Get sick | |
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~kpm~ (OP) User ID: 75950402 United States 02/10/2020 11:41 AM Report Abusive Post Report Copyright Violation | The good news is that “we now have a variety of therapeutic options to treat cytokine storm syndrome,” Cron said. “But especially a lot of the older physicians don’t know what this is.” That was one of Cron’s primary motivating factors in writing his book, he said. “Cytokine Storm Syndrome” offers detailed descriptions of symptoms and clinical presentations, along with the latest treatments and care regimens. “The sooner you recognize it, the better the outcomes,” Cron said. “If we can get people to diagnose this in the ER and the ICU, that would be ideal.” [link to www.uab.edu (secure)] Based on the promising results mentioned above, combination therapies pairing S1PR and PPAR agonists, COX-2 inhibitors, and antioxidants with conventional antiviral agents are promising treatments that deserve further study in randomized clinical trials. Other approaches, especially those therapeutic strategies that can target signaling pathways, either to suppress redundant immune responses or reduce viral replication, will be particularly noteworthy. Therapies in link...... [link to www.ncbi.nlm.nih.gov (secure)] Last Edited by ~kpm~ on 02/10/2020 02:22 PM ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 11:42 AM Report Abusive Post Report Copyright Violation | You’re welcome I know we are all looking for ways to stay healthy but I feel this is probably one the the most significant symptoms we should all be aware of if we become ill! ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
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~kpm~ (OP) User ID: 75950402 United States 02/10/2020 11:46 AM Report Abusive Post Report Copyright Violation | “Probably the sickest patient I ever saw come out of the ICU unscathed.” The doctors treated her with anakinra, a cytokine-targeting therapy that was approved to treat the autoimmune disease rheumatoid arthritis. “She turned around and it was magical,” Cron recalled. “We’re both research scientists, so he developed a mouse model [of cytokine storm syndrome] and I’ve been studying the genetic and human aspects. We’ve identified new genes not previously described as a part of this genetic workup.” [link to www.uab.edu (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 11:49 AM Report Abusive Post Report Copyright Violation | I appreciate the tip. Quoting: Anonymous Coward 77901425 Although I thought once you actually hit cytokine storm stage you're pretty much done for, test or no test. The idea is to prevent that. megadoses of vitamin C? IMO, if I were to get any flu type symptoms I’m asking for that test ASAP I had a friend who died in 3 days after getting step and her symptoms sound exactly like cytokine storm We can all take precautions of course I’m not schooled enough on vitamin C but anything that boosts our immune system can’t be bad ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 11:53 AM Report Abusive Post Report Copyright Violation | But for other patients, new treatments can calm the storm and bring remarkable recoveries. Cron and Behrens “both got interested in this through a patient we saw in Pennsylvania,” Cron said. Quoting: ~kpm~ “Probably the sickest patient I ever saw come out of the ICU unscathed.” The doctors treated her with anakinra, a cytokine-targeting therapy that was approved to treat the autoimmune disease rheumatoid arthritis. “She turned around and it was magical,” Cron recalled. “We’re both research scientists, so he developed a mouse model [of cytokine storm syndrome] and I’ve been studying the genetic and human aspects. We’ve identified new genes not previously described as a part of this genetic workup.” [link to www.uab.edu (secure)] Anakinra is used, alone or in combination with other medications, to reduce the pain and swelling associated with rheumatoid arthritis. Anakinra is in a class of medications called interleukin antagonists. It works by blocking the activity of interleukin, a protein in the body that causes joint damage. [link to medlineplus.gov (secure)] Evidence for use of siltuximab or anakinra as second line therapies (after failure of tocilizumab) for Cytokine Release Syndrome (CRS) following use of Chimeric Antigen Receptor T-cell (CAR-T) therapy [link to www.sps.nhs.uk (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:02 PM Report Abusive Post Report Copyright Violation | In this publication, Huang, et al. describe the characteristics and clinical course of hospitalized patients infected with the Wuhan coronavirus who did, or did not, require treatment in the intensive care unit (ICU). Those that were admitted to the ICU, particularly those with severe disease, exhibited significantly higher levels of inflammatory cytokines compared to those that did not. This "cytokine storm" can trigger a viral sepsis in coronavirus infection, where viral replication and excessive, uncontrolled systemic inflammation can lead to pneumonitis, acute respiratory distress syndrome, respiratory failure, shock, organ failure, secondary bacterial pneumonia, and potentially death. This same correlation between cytokine storm and severity of illness was observed previously in both SARS and MERS patients. Dr. Phillip Chan, MD, PhD, Chief Executive Officer of CytoSorbents stated, "CytoSorb has been used to control deadly inflammation in tens of thousands of treatments in patients with either bacterial or viral sepsis. Although CytoSorb has not yet been specifically used to treat patients infected with this newly emergent coronavirus, we believe it can play an important role, with or without anti-viral therapies, in the treatment of this highly inflammatory illness." [link to www.ptcommunity.com (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:10 PM Report Abusive Post Report Copyright Violation | Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China [link to www.thelancet.com (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:15 PM Report Abusive Post Report Copyright Violation | CytoSorb, the Wuhan Coronavirus, and Cytokine Storm [link to www.prnewswire.com (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:16 PM Report Abusive Post Report Copyright Violation | CYTOSORBENTS OFFICIALLY OPENS NEW U.S. CYTOSORB MANUFACTURING FACILITY [link to cytosorbents.com (secure)] ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
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~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:21 PM Report Abusive Post Report Copyright Violation | I think we need to be equipped with as much info as we can get I’m gonna compile this info and protocol so that I have it handy, just in case ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:21 PM Report Abusive Post Report Copyright Violation | Thanks for the pin! ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
Loup Garou User ID: 31702506 United States 02/10/2020 12:24 PM Report Abusive Post Report Copyright Violation | Thanks for this life saving info. serum ferritin Just because YOU don’t believe in the Rougarou; or the Loup Garou, don’t make you safe; No ! The Constitution is a blend of 'moral certitude' -- which is one of the reasons that criminals are determined to be rid of it and We the People must be even more determined to defend it. "If there must be trouble, let it be in my day, that my child may have peace." - Thomas Paine The only thing the Illuminati fears is an independent person who can live, eat, sleep, stay warm and defend themselves separate from Federal help. Pray that the Lord gives us more time! The End is near and time is short! A fool takes no pleasure in understanding, but only in expressing his opinion. ~Proverbs 18:2 For those who understand, no explanation is needed. For those who do not understand, no explanation is possible "A candle loses nothing by lighting another candle" - James Keller Checkd, Keked, and Rekt! #Kids2 |
Anonymous Coward User ID: 34393126 United States 02/10/2020 12:25 PM Report Abusive Post Report Copyright Violation | Keep this in mind.... Quoting: ~kpm~ I was reading an article yesterday, this may be helpful if you end up at the hospital or sick Ask for this test, the earlier found the better Cheap, simple test Symptoms include high fever, enlarged spleen, excessive bleeding, low counts of all types of blood cells (red, white and platelets) and, potentially, multiple organ failures. A cheap, simple test, widely available at most hospitals in the United States and worldwide, can help diagnose cytokine storm syndrome, Cron said. “A protein called serum ferritin tends to get very high in this disorder,” he said. “If you are sick enough to be in a hospital and you have a fever, you should get a serum ferritin. It typically comes back in less than 24 hours and almost every hospital can do it, and if it’s high you can work them up for cytokine storm syndrome.” [link to www.uab.edu (secure)] . 5 stars and added to favorites! |
Louis in Richmond That is my arm now; broken for 7 months User ID: 3079061 United States 02/10/2020 12:29 PM Report Abusive Post Report Copyright Violation | Thank you ~KPM~ this may save lives!! Until your military service has required you neutralize enemy combatants and invaders in the defense of your country, don't presume to tell us that have defended you that you don't support every shot we fired to eliminate that enemy. |
Anonymous Coward User ID: 73799821 United States 02/10/2020 12:30 PM Report Abusive Post Report Copyright Violation | I urge everyone to make a print out of possible tests and drugs that may help if you should become sick and or end up at the hospital Quoting: ~kpm~ Add it to your list of daily meds so that you can discuss your treatment options Keep this in mind....although the numbers are not up to date the R0 seems to be rising It took eight months for SARS to spread to more than 8,000 people. The Wuhan coronavirus infected over 20,000 people in about five weeks. One month into SARS outbreak, only five people had died. The new coronavirus had killed at least 213 people by the one-month mark. [link to www.businessinsider.com (secure)] In the past week, at least six teams of researchers, along with the World Health Organization, have published estimates of R0 for the new coronavirus. All these groups used different methods, but their results have been mostly consistent, with estimates hovering between 2 and 3. WHO was a little more conservative than the others, with estimates of 1.4 to 2.5. One Chinese team is a clear outlier, with estimates of 3.3 to 5.5. And a British-led group initially published a high average value of 3.8 last week before revising it downward to 2.5 as new data emerged. [link to www.theatlantic.com (secure)] Cheap, simple test Symptoms include high fever, enlarged spleen, excessive bleeding, low counts of all types of blood cells (red, white and platelets) and, potentially, multiple organ failures. A cheap, simple test, widely available at most hospitals in the United States and worldwide, can help diagnose cytokine storm syndrome, Cron said. “A protein called serum ferritin tends to get very high in this disorder,” he said. “If you are sick enough to be in a hospital and you have a fever, you should get a serum ferritin. It typically comes back in less than 24 hours and almost every hospital can do it, and if it’s high you can work them up for cytokine storm syndrome.” [link to www.uab.edu (secure)] . so why don't you just say what that test is jesus christ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:37 PM Report Abusive Post Report Copyright Violation | I urge everyone to make a print out of possible tests and drugs that may help if you should become sick and or end up at the hospital Quoting: ~kpm~ Add it to your list of daily meds so that you can discuss your treatment options Keep this in mind....although the numbers are not up to date the R0 seems to be rising It took eight months for SARS to spread to more than 8,000 people. The Wuhan coronavirus infected over 20,000 people in about five weeks. One month into SARS outbreak, only five people had died. The new coronavirus had killed at least 213 people by the one-month mark. [link to www.businessinsider.com (secure)] In the past week, at least six teams of researchers, along with the World Health Organization, have published estimates of R0 for the new coronavirus. All these groups used different methods, but their results have been mostly consistent, with estimates hovering between 2 and 3. WHO was a little more conservative than the others, with estimates of 1.4 to 2.5. One Chinese team is a clear outlier, with estimates of 3.3 to 5.5. And a British-led group initially published a high average value of 3.8 last week before revising it downward to 2.5 as new data emerged. [link to www.theatlantic.com (secure)] Cheap, simple test Symptoms include high fever, enlarged spleen, excessive bleeding, low counts of all types of blood cells (red, white and platelets) and, potentially, multiple organ failures. A cheap, simple test, widely available at most hospitals in the United States and worldwide, can help diagnose cytokine storm syndrome, Cron said. “A protein called serum ferritin tends to get very high in this disorder,” he said. “If you are sick enough to be in a hospital and you have a fever, you should get a serum ferritin. It typically comes back in less than 24 hours and almost every hospital can do it, and if it’s high you can work them up for cytokine storm syndrome.” [link to www.uab.edu (secure)] . so why don't you just say what that test is jesus christ To much reading for you? Some people like the background reading to judge if it seems credible The test name is in the OP ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
beeches User ID: 77354011 United States 02/10/2020 12:47 PM Report Abusive Post Report Copyright Violation | other common conditions can elevate ferritin levels to varying degrees [link to www.bmj.com (secure)] The bottom line •-Elevated ferritin levels are usually due to causes such as acute or chronic inflammation, chronic alcohol consumption, liver disease, renal failure, metabolic syndrome, or malignancy rather than iron overload •-Exclude these causes clinically or with initial tests such as full blood count, liver and renal function, and inflammatory markers (C reactive protein or erythrocyte sedimentation rate) •-A normal serum transferrin saturation (ideally fasting) usually excludes iron overload (where it is raised) and suggests a reactive cause for raised ferritin •-Unexplained serum ferritin values >1000g/L warrant referral for further investigation •-Consider HFE mutation screen for hereditary haemochromatosis in individuals with elevated ferritin and a raised transferrin saturation >45% ------------------- bolded the one that may apply here.... highly elevated levels without other explanations.. Last Edited by beeches on 02/10/2020 12:48 PM Liberalism is totalitarianism with a human face – Thomas Sowell |
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~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:53 PM Report Abusive Post Report Copyright Violation | other common conditions can elevate ferritin levels to varying degrees Quoting: beeches [link to www.bmj.com (secure)] The bottom line •-Elevated ferritin levels are usually due to causes such as acute or chronic inflammation, chronic alcohol consumption, liver disease, renal failure, metabolic syndrome, or malignancy rather than iron overload •-Exclude these causes clinically or with initial tests such as full blood count, liver and renal function, and inflammatory markers (C reactive protein or erythrocyte sedimentation rate) •-A normal serum transferrin saturation (ideally fasting) usually excludes iron overload (where it is raised) and suggests a reactive cause for raised ferritin •-Unexplained serum ferritin values >1000g/L warrant referral for further investigation •-Consider HFE mutation screen for hereditary haemochromatosis in individuals with elevated ferritin and a raised transferrin saturation >45% ------------------- bolded the one that may apply here.... highly elevated levels without other explanations.. Yup, if you have flu like symptoms I would definitely demand the test ASAP ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
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~kpm~ (OP) User ID: 75950402 United States 02/10/2020 12:55 PM Report Abusive Post Report Copyright Violation | I’ve read info that nicotine assists prevention of cytokine storm, and I’ve seen a few people here note that they have nic patches, but how do you know when to use them? Quoting: Anonymous Coward 76862206 If you read up on some of the protocol they are using to combat cytokine storm that I posted, I would not rely on nicotine patches to save you and or protect you I have no idea if this works so do it at your own risk or ask a doctor Google cytokine storm and nicotine therapy . Last Edited by ~kpm~ on 02/10/2020 12:59 PM ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
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Anonymous Coward User ID: 76809123 United States 02/10/2020 01:08 PM Report Abusive Post Report Copyright Violation | Your lifestyle plays a huge role in cytokine expression. These steps can help tame the storm: Exercise regularly. Exercising at least two to three days per week can calm pro-inflammatory cytokines and greatly lessen pain. This includes walking, pilates, weight lifting, or whatever you enjoy. Cut out inflammatory foods. Such as gluten, dairy, conventional meats, nightshades, oxalates, and legumes. If you experience serious pain, consider the GAPS diet to lower inflammation. Be sure to drink at least 8 ounces of filtered water daily. In the middle of a detox? Drink more! Get at least 8 hours of sleep each night. (Read about how to improve your sleep here.) Stimulate your vagus nerve and laugh, meditate, pray, or sing daily! Get rid of negative thoughts. Instead, focus on positive affirmations or Bible verses daily. |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 01:08 PM Report Abusive Post Report Copyright Violation | It’s best to best as educated and proactive in your treatment, if needed I always question doctors and won’t hesitate to mention this if needed ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |
~kpm~ (OP) User ID: 75950402 United States 02/10/2020 01:10 PM Report Abusive Post Report Copyright Violation | Your lifestyle plays a huge role in cytokine expression. These steps can help tame the storm: Quoting: Anonymous Coward 76809123 Exercise regularly. Exercising at least two to three days per week can calm pro-inflammatory cytokines and greatly lessen pain. This includes walking, pilates, weight lifting, or whatever you enjoy. Cut out inflammatory foods. Such as gluten, dairy, conventional meats, nightshades, oxalates, and legumes. If you experience serious pain, consider the GAPS diet to lower inflammation. Be sure to drink at least 8 ounces of filtered water daily. In the middle of a detox? Drink more! Get at least 8 hours of sleep each night. (Read about how to improve your sleep here.) Stimulate your vagus nerve and laugh, meditate, pray, or sing daily! Get rid of negative thoughts. Instead, focus on positive affirmations or Bible verses daily. Yup, we have to do preventive things to make us as strong as we can be should this spread there ~With forethought and malice Whitless enacted an EO giving nursing homes immunity from wrongful death prosecutions, forced them to take in infected patients and is responsible for over 6500+ nursing home deaths~ |