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WHO scientist holds patent of bioengineered swine flue virus

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Anonymous Coward
User ID: 643996
10/30/2009 7:07 PM
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WHO scientist holds patent of bioengineered swine flue virus

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WHO scientist holds patent of bioengineered swine flue virus
A scientist, who heads a WHO laboratory on influenza holds patent for bioengineered swine flu virus!

US Patent Application 20090010962 - Genetically Engineered Swine Influenza Virus and Uses Thereof

[link to www.patentstorm.us]

Claims 1. An attenuated swine influenza virus comprising a mutation in a swine influenza NS1 gene that diminishes the ability of the NS1 gene product to antagonize the cellular interferon response, and permits the attenuated virus, at a multiplicity of infection of 0.001, to grow to titers between approximately 3 fold to approximately 7 fold lower than wild-type swine influenza in pig cells, as determined approximately 5 days post-infection when propagated under the same conditions. 2. The attenuated swine influenza virus of claim 1, wherein the attenuated virus is genetically engineered. 3. The attenuated swine influenza virus of claim 1, wherein the attenuated virus is a mutagenized virus or reassortant. 4. The attenuated swine influenza virus of claim 2, wherein the attenuated virus is a chimeric virus that expresses a heterologous sequence. 5. The attenuated swine influenza virus of claim 2, wherein the attenuated virus is a chimeric virus that expresses a tumor antigen. 6. The attenuated swine influenza virus of claim 2, wherein the attenuated virus is a chimeric virus that expresses an epitope of a foreign pathogen. 7. The attenuated swine influenza virus of claim 1, wherein pig cells are PK(D1) cells, PK(15) cells, PK13 cells, NSK cells, LLC-PK1 cells, LLC-PK1A cells, ESK-4 cells, ST cells, PT-K75 cells, PK-2a/CL 13 cells or SJPL cells. 8. (canceled) 9. The attenuated swine influenza virus of claim 2, wherein the mutation is a deletion at the carboxy terminus of the NS1 gene. 10. (canceled) 11. An attenuated swine influenza virus comprising a modified NS1 gene, wherein the attenuated swine influenza virus is TX/98/del 126, TX/98/del 99 or TX/98/del 73. 12. An attenuated swine influenza virus having an altered interferon antagonist phenotype, wherein said virus comprises a mutation in the NS1 gene resulting in a deletion of between the 105 carboxy terminal amino acid residues and the 160 carboxy terminal amino acid residues of NS1. 13. The attenuated swine influenza virus of claim 12, wherein the virus is attenuated by a mutation in the NS1 gene resulting in a deletion of all of the amino acid residues of NS1 except amino acid residues 1-95, amino acid residues 1-90, amino acid residues 1-85, amino acid residues 1-80, amino acid residues 1-75, amino acid residues 1-73, amino acid residues 1-70, amino acid residues 1-65, or amino acid residues 1-60, and wherein the amino terminal amino acid is number 1 and the mutation in the NS1 gene confers an altered interferon antagonist phenotype. 14. (canceled)

Link to scientists who hold the patent:

1. Robert G. Webster (holds also a high position within the WHO)
[link to en.wikipedia.org]

2. Dr. Jürgen A. Richt
[link to www.immunobiology.iastate.edu]

3. Richard J. Webby
[link to www.stjude.org]

4. Peter Palese
[link to www.mountsinai.org]

5. Adolfo García-Sastre
[link to www.mssm.edu]

[link to disclose.tv]

Anonymous Coward
User ID: 643996 (OP)
10/30/2009 7:11 PM

Re: WHO scientist holds patent of bioengineered swine flue virus	Quote

Sir.Kalin
User ID: 806632
10/30/2009 7:13 PM

Re: WHO scientist holds patent of bioengineered swine flue virus

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- Jesus paid for our sins, now let's get our money's worth.

- The only hot-dog that needs a warning label is the 'Barney Frank'.

- You can’t argue with reason against a position that isn’t based on reason.

- Those who just want 'free-will' and don't exercise it, would not be capable of keeping it if they had it.

- Isaiah 45:7 - "I form the light, and create darkness: I make peace, and create evil: I the LORD do all these things."

Anonymous Coward
User ID: 803970
10/30/2009 7:15 PM

Re: WHO scientist holds patent of bioengineered swine flue virus	Quote
Quoting: Anonymous Coward 643996

Anonymous Coward
User ID: 526297
10/30/2009 7:25 PM

Re: WHO scientist holds patent of bioengineered swine flue virus	Quote
Things that make you go HMMMMMMMMMM ...

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