I'm a bio-chemist, and a nutritionist and I've been personally using and recommending Benfotiamine to clients for several years with remarkable results.

It is a fat-soluble form of B-1, and thus stays in the system way longer, and isn't "peed out" right away. I've had great success with less than 1 gram per day. I use Life Extension products personally and in my practice and they are amongst the best. For Benfotiamine I use Swanson Health Products which is the number one rated online and catalog vitamin company in the world because you can get the same product less money. They have a 160 mg size for $5, and the 300 mg size for $10 and even using 2/day it costs between $5 and $10 per month for a bottle of 60 capsules (320 mg to 600 mg per day).

Benfotiamine is also amazingly good for the circulatory system and kidneys in addition to the neuropathy benefits. That is what I use it for. In addition to Benfotiamine, I would add R-Alpha Lipoic acid, Enteric coated 2400 unit strength Bromelain 500mg, and 95% Curcumin 500 mg which are a fabulous adjunct for serious cases of neuropathy.

I hope this helps!