From the personal experience of a family member, I can share that heavy LSD use as a teenager and young adult (friend was in a travelling, semi-successful rock band in the 1970's), results in permanently changing the brain in terms of brain serotonin uptake.

The person is 'hooked' on anything that duplicates the 'pleasure'.

This includes future alcohol addiction.

It goes both ways. The alcoholic wants drugs again.

So really, from the level of physiology, there is no difference between intoxicants of any kind.

What is not discussed by the medical literature, of course, are the social, empathic, and spiritual results of 'masturbating your mind' with hallucinogens.,, which include alcohol.

The only treatment is abstinence, backed by the decision to totally renounce this form of self-destructive behavior.