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ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!

 
DoorBert
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ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
First Ebola patient diagnosed in US won’t be treated with ZMapp

Stocks of experimental drug used to treat several international health workers – at least two of them Americans – have run out

The Ebola patient in Dallas will not be given ZMapp, the experimental drug used to treat several international aid workers and medical staff, including at least two Americans, because stocks have run out.

ZMapp is one of the drugs that is being rushed into trials in the epidemic, along with other drugs that will need more safety data in animals and humans before they are administered to patients.

There have been very few doses available and stocks have now all been used up, but the San Diego-based company behind ZMapp is now pressing ahead with the manufacture of more supplies. It is not an easy drug to make, however. It includes three man-made antibodies to the virus which are grown in tobacco leaves and takes months to produce.

[link to www.theguardian.com]

Last Edited by DoorBert on 10/01/2014 09:00 AM
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Obama Briefed

The CDC and Texas doctors are discussing the use of possible experimental treatments, Frieden said, though no decision has been made.

President Barack Obama was briefed about the patient by Frieden, the White House said in a statement. They discussed the patient’s treatment and what was being done to trace the people the man might have contacted.

[link to www.bloomberg.com]
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
BREAKING: There may already be another #Ebola case in Dallas.

DCHHS is investigating family member of the infected patient.



[link to twitter.com]
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Check out ticker symbol LAKE.

Up 12% pre-market.

They make the Ebola Hazmat Suites.
DoorBert  (OP)

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10/01/2014 09:14 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
A company that makes hazmat suits is surging after the CDC confirms first US Ebola case

[link to www.businessinsider.com]
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
CDC to hold press conference at 5:30PM EDT

[link to www.cnn.com]
Anonymous Coward
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10/01/2014 09:58 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
you said brief!
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Much thanks for pin!
Southern Lighthouse

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
BREAKING: There may already be another #Ebola case in Dallas.

DCHHS is investigating family member of the infected patient.



[link to twitter.com]
 Quoting: DoorBert


Oh shit, here we go.

verysad
Love is the highest form of spiritual warfare.
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
DR Congo Ebola outbreak has killed 42 since August

[link to www.france24.com]
DoorBert  (OP)

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Glenn Beck: Re Ebola-whatever the gov't tells you to do, do the opposite. They've been wrong on everything. True dat.
Anonymous Coward
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10/01/2014 10:12 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Save us president Obola!
Black Unit

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10/01/2014 10:33 AM

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Uh huh, more like all doses have been saved for the Rich and politically connected.
Anonymous Coward
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10/01/2014 10:42 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
The main guy came down with symptoms 13 years, 13 days after 9/11.
TeamReaper

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10/01/2014 10:43 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
He came into contact with 12-18 people after being contagious (Sept 24th or later


In every operation, whether planning it or executing it, you can never count on luck; but you have to accept it, and recognize it when it’s there.
-Major ******, U-2 Pilot/Instructor/Flight Commander
Anonymous Coward
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Uh huh, more like all doses have been saved for the Rich and politically connected.
 Quoting: Black Unit


:dog1: Yup thats what I'm thinking too.
Anonymous Coward
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10/01/2014 10:46 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
But for the few doses, it had a great impact....

IT CONVINCED AFRICA THAT IF YOU WANT TO LIVE, YOU JUMP ON A PLANE TO AMERICA.

Heckuva job, Obamie
Anonymous Coward
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10/01/2014 10:52 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
It is all about who he had contact with.

What about how he got it?

Due to the timing, it could have been contracted anywhere.

Could have been caught in the US, on the plane or in Africa.

If he caught it on the plane, well, that is the worst case scenario ever.
Anonymous Coward
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
It is all about who he had contact with.

What about how he got it?

Due to the timing, it could have been contracted anywhere.

Could have been caught in the US, on the plane or in Africa.

If he caught it on the plane, well, that is the worst case scenario ever.
 Quoting: Anonymous Coward 58351648


This is where it will explode into an epidemic. We are not considering others around him when he caught it. What about people who were exposed near him? Being it could have been on the plane he caught it, that is very possible and no one official is considering it, yet it is a REAL possibility.

The officials are in damage control and trying to prevent panic. Which, the panic itself could cause more harm then good by breaking the very system that can control it.
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10/01/2014 10:55 AM

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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Sense 5’-GmUACGAAGCUmGUAUAmUAAAUU-3’, antisense 5’-UUUAmUAUACAGCUUCGmUACAA-3’
Sense 5’-UCCmUCGACACGAAmUGCAAAGU-3’, antisense 5’-UUmUGCAUUCGUGUCmGAGmGAUC-3’
Sense 5’-GCAACmUCAUUGmGrArCrAmUCAUUC-3’, antisense 5’-AUGAUmGUCCAAUGAmGUmUGCUA-3’
Probably already too late for the DFW patient anyway, but if I was potential patient #2 I'd be begging to start taking the above SNALP-formulated anti-ZEBOV siRNAs immediately. Unlike ZMAPP it can be manufactured relatively quickly, without needing to wait months for tobacco plants to grow. Unfortunately since the FDA stopped the phase I clinical trial, I seriously doubt they will administer it to any patients. I would personally be willing to take the risk if it were my skin on the line though.
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
First Ebola patient diagnosed in US won’t be treated with ZMapp

Stocks of experimental drug used to treat several international health workers – at least two of them Americans – have run out

The Ebola patient in Dallas will not be given ZMapp, the experimental drug used to treat several international aid workers and medical staff, including at least two Americans, because stocks have run out.

ZMapp is one of the drugs that is being rushed into trials in the epidemic, along with other drugs that will need more safety data in animals and humans before they are administered to patients.

There have been very few doses available and stocks have now all been used up, but the San Diego-based company behind ZMapp is now pressing ahead with the manufacture of more supplies. It is not an easy drug to make, however. It includes three man-made antibodies to the virus which are grown in tobacco leaves and takes months to produce.

[link to www.theguardian.com]
 Quoting: DoorBert




Wait wait wait! TOBACCO???? Could THIS be what's been behind the big gubb'mint push for smoking cessation all these years? So that we wouldn't be immune to their manufactured virus?

I wonder if the big tobacco companies are/will be financially profiting from the manufacture of this antidote?
"I have come to the conclusion that all news should be treated like 9/11, assume it is a psyop with actors participating in a staged event complete with props, until proven otherwise, in which case assume whatever is being recorded, reported, televised, is distortions/lying by omission/outright lies, until proven otherwise." - Anonymous, 4-13-12
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
you said brief!
 Quoting: Anonymous Coward 63490329




Yes, where IS Brief, anyway? You'd think that he would have some pithy comments concerning the situation.....!
"I have come to the conclusion that all news should be treated like 9/11, assume it is a psyop with actors participating in a staged event complete with props, until proven otherwise, in which case assume whatever is being recorded, reported, televised, is distortions/lying by omission/outright lies, until proven otherwise." - Anonymous, 4-13-12
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
He came into contact with 12-18 people after being contagious (Sept 24th or later


 Quoting: TeamReaper




Well, until he remembers that he stopped at Safeway for aspirin on the way home from the hospital the first time.

Can you imagine what a nightmare THAT could be? To locate all those shoppers and their families, and then locating everyone whom THEY had come in contact with......

I'm really surprised that the Sci-Fi Channel hasn't re-broadcast Steven King's "The Stand" on their weekend line-up yet. The viewership numbers would probably rival the "Sharknado" movies!
"I have come to the conclusion that all news should be treated like 9/11, assume it is a psyop with actors participating in a staged event complete with props, until proven otherwise, in which case assume whatever is being recorded, reported, televised, is distortions/lying by omission/outright lies, until proven otherwise." - Anonymous, 4-13-12
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
First Ebola patient diagnosed in US won’t be treated with ZMapp

Stocks of experimental drug used to treat several international health workers – at least two of them Americans – have run out

The Ebola patient in Dallas will not be given ZMapp, the experimental drug used to treat several international aid workers and medical staff, including at least two Americans, because stocks have run out.

ZMapp is one of the drugs that is being rushed into trials in the epidemic, along with other drugs that will need more safety data in animals and humans before they are administered to patients.

There have been very few doses available and stocks have now all been used up, but the San Diego-based company behind ZMapp is now pressing ahead with the manufacture of more supplies. It is not an easy drug to make, however. It includes three man-made antibodies to the virus which are grown in tobacco leaves and takes months to produce.

[link to www.theguardian.com]
 Quoting: DoorBert




Wait wait wait! TOBACCO???? Could THIS be what's been behind the big gubb'mint push for smoking cessation all these years? So that we wouldn't be immune to their manufactured virus?

I wonder if the big tobacco companies are/will be financially profiting from the manufacture of this antidote?
 Quoting: Eggcellent


No. It's not about smoking regular tobacco. It's about genetically engineering related plants to produce desired proteins, even antibodies. They use Nicotiana benthamiana for ZMAPP, not regular tobacco plants (Nicotiana tabacum). Nicotiana benthamiana is particularly susceptible to disease, which makes it less than ideal for big tobacco companies, but extremely ideal for scientists who can deliberately infect it with bacteria that are modified to carry genes of interest and thereby use the plant as a biological factory.
[link to www.rtnz.com]
I studied under Dr. Henry Daniell during my undergrad years, he wrote the letter of recommendation that got me into my PhD program. He was a pioneer in this field. He pioneered the process of engineering the chloroplasts to produce the desired proteins, so that the transgenes could not spread through the pollen (among other reasons).

Last Edited by Astromut on 10/01/2014 11:13 AM
astrobanner2
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
ZMAPP ran out a month ago and there will be NONE available till January 2015 and when that time comes around there will be only available a few hundred doses at MAX because this serum will never ever be able to be mass produced due to its nature. so all of you in the USA keep this is in mind, that your government will not be able to save you! what you need to do is not get ebola in the first place and right now that means wear gloves when going out in public and not going in near people within 3 feet of space.
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
This was posted on Youtube on Sep 16, 2014

[link to youtu.be]
Anonymous Coward
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10/01/2014 11:15 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Is it just me, or does Frieden almost act giddy??
Anonymous Coward
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10/01/2014 11:17 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Vaccine tested. How convenient that they has something about ready.

[link to www.npr.org]

Ebola will go nuts and terrify everyone.

Then they will finish or suspend the tests to rush out the vaccine.

Frightened, bleating sheep will lineup for the vaccine shearing.
Zcat

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10/01/2014 11:17 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
wtf wtf wtf! This sucks ass! Shoulda said no enter without bloodtest.

I hope any secondary infected survivors sue the ever-loving shit outta the airlines! That is stream of commerce and gross negligence.
Zcat
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Wait wait wait! TOBACCO???? Could THIS be what's been behind the big gubb'mint push for smoking cessation all these years? So that we wouldn't be immune to their manufactured virus?

I wonder if the big tobacco companies are/will be financially profiting from the manufacture of this antidote?
 Quoting: Eggcellent


No. It's not about smoking regular tobacco. It's about genetically engineering related plants to produce desired proteins, even antibodies. They use Nicotiana benthamiana for ZMAPP, not regular tobacco plants (Nicotiana tabacum). Nicotiana benthamiana is particularly susceptible to disease, which makes it less than ideal for big tobacco companies, but extremely ideal for scientists who can deliberately infect it with bacteria that are modified to carry genes of interest and thereby use the plant as a biological factory.
[link to www.rtnz.com]
I studied under Dr. Henry Daniell during my undergrad years, he wrote the letter of recommendation that got me into my PhD program. He was a pioneer in this field. He pioneered the process of engineering the chloroplasts to produce the desired proteins, so that the transgenes could not spread through the pollen (among other reasons).
 Quoting: Dr. Astro




Wow! Thank you Dr. Astro for taking the time to explain that, and in a perfectly understandable way. hf
"I have come to the conclusion that all news should be treated like 9/11, assume it is a psyop with actors participating in a staged event complete with props, until proven otherwise, in which case assume whatever is being recorded, reported, televised, is distortions/lying by omission/outright lies, until proven otherwise." - Anonymous, 4-13-12
TeamReaper

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10/01/2014 11:32 AM
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Re: ZMAPP Supply Runs Out. Dallas Patient not to be Treated with Drug. Obola Briefed. Reports of a 2nd Case being Investigated!
Info on 2nd case

[link to www.usatoday.com]
In every operation, whether planning it or executing it, you can never count on luck; but you have to accept it, and recognize it when it’s there.
-Major ******, U-2 Pilot/Instructor/Flight Commander





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