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PERIODONTAL Disease and Pancreatic CANCER - link found

Anonymous Coward
User ID: 189771
United States
02/02/2007 11:24 PM
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PERIODONTAL Disease and Pancreatic CANCER - link found
They found out how gum disease is related to pancreatic cancer, but there is more to it, on two fronts - other cancers from bacteria, and other diseases from dental.

1] - many cancers are related to bacterial and viral infections, possibly a CTP OTS tactic. This has been ignored until recently, but we will find that many cancers can be beat or avoided by bacterial controls, like Colloidal Silver.

2] - many other illnesses will be found to be caused by our dental condition. For many, the best option just might be complete extractions, but dentists are hesitant to do this. They sometimes say they will just to scare you, and then refuse to do it saying "we are in the business of SAVING teeth", which sounds reasonable.
But for me, it was not, and it took over 5 years to get them all out and then my headaches and Fibromyalgia pains went away. Chronic Fatigue too - gone. I still have gut problems, but hey, it was well worth it - dentures are not so bad.
Root Canaled teeth are highly supicious if you have chronic illness, and fillings and cracked teeth or otherwise 'comprimised enamel' is inviting bacterial infections.

Link Found Between Periodontal Disease and Pancreatic Cancer

Newswise — Pancreatic cancer is the fourth leading cause of cancer death in the U.S.; more than 30,000 Americans are expected to die from the disease this year. It is an extremely difficult cancer to treat and little is known about what causes it. One established risk factor in pancreatic cancer is cigarette smoking; other links have been made to obesity, diabetes type 2 and insulin resistance. In a new study, researchers at the Harvard School of Public Health (HSPH) and Dana-Farber Cancer Institute found that periodontal disease was associated with an increased risk of cancer of the pancreas. The study will appear in the January 17, 2007 issue of the Journal of the National Cancer Institute.

“Our study provides the first strong evidence that periodontal disease may increase the risk of pancreatic cancer. This finding is of significance as it may provide some new insights into the mechanism of this highly fatal disease,” said lead author Dominique Michaud, assistant professor of epidemiology at HSPH.

Periodontal disease is caused by bacterial infection and inflammation of the gums that over time causes loss of bone that supports the teeth; tooth loss is a consequence of severe periodontal disease. Two previous studies had found a link between tooth loss or periodontitis and pancreatic cancer, but one consisted of all smokers and the other did not control for smoking in the analysis, and therefore no firm conclusions could be drawn from these studies.

Data for the new study came from the Health Professionals Follow-Up Study, which began in 1986 and includes 51,529 U.S. men working in the health professions. Participants respond to questionnaires about their health every two years. After analyzing the data, the researchers confirmed 216 cases of pancreatic cancer between 1986 and 2002; of those, 67 reported periodontal disease.

The results showed that, after adjusting for age, smoking, diabetes, body mass index and a number of other factors, men with periodontal disease had a 63% higher risk of developing pancreatic cancer compared to those reporting no periodontal disease. “Most convincing was our finding that never-smokers had a two-fold increase in risk of pancreatic cancer,” said Michaud.

One possible explanation for the results is that inflammation from periodontal disease may promote cancer of the pancreas. “Individuals with periodontal disease have elevated serum biomarkers of systemic inflammation, such as C-reactive protein, and these may somehow contribute to the promotion of cancer cells,” she said.

Another explanation, according to Michaud, is that periodontal disease could lead to increased pancreatic carcinogenesis because individuals with periodontal disease have higher levels of oral bacteria and higher levels of nitrosamines, which are carcinogens, in their oral cavity. Prior studies have shown that nitrosamines and gastric acidity may play a role in pancreatic cancer.

Michaud, senior author Charles Fuchs, a gastrointestinal oncologist at Dana-Farber, and their colleagues believe that further studies should be done to investigate the role of inflammation from periodontal disease in pancreatic cancer. However, Michaud notes that the underlying mechanisms for this association are speculative at this point. “More research is needed both to confirm this finding in other populations and also to explore the role of inflammation in this particular cancer,” she said.


User ID: 4702
United States
02/03/2007 12:09 PM
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Re: PERIODONTAL Disease and Pancreatic CANCER - link found
This link is very important to know.

Thank you.

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