Prozac

February 1990 American Journal of Psychiatry (Teicher et al, v.147:207-210) reports on “six depressed patients, previously free of recent suicidal ideation, who developed `intense, violent suicidal preoccupations after 2-7 weeks of fluoxetine [Prozac] treatment.’ The suicidal preoccupations lasted from three days to three months after termination of the treatment. The report estimates that 3.5 percent of Prozac users were at risk. While denying the validity of the study, Dista Products, a division of Eli Lilly, put out a brochure for doctors dated August 31, 1990, stating that it was adding `suicidal ideation’ to the adverse events section of its Prozac product information.”

An earlier study, from the September 1989 Journal of Clinical Psychiatry, by Joseph Lipiniski, Jr., indicates that in five examined cases people on Prozac developed what is called akathesia. Symptoms include intense anxiety, inability to sleep, the “jerking of extremities,” and “bicycling in bed or just turning around and around.” Dr. Peter Breggin comments that akathesia “may also contribute to the drug’s tendency to cause self-destructive or violent tendencies … Akathesia can become the equivalent of biochemical torture and could possibly tip someone over the edge into self-destructive or violent behavior … The June 1990 Health Newsletter, produced by the Public Citizen Research Group, reports, ‘Akathesia, or symptoms of restlessness, constant pacing, and purposeless movements of the feet and legs, may occur in 10-25 percent of patients on Prozac.’”

The well-known publication, California Lawyer, in a December 1998 article called “Protecting Prozac,” details some of the suspect maneuvers of Eli Lilly in its handling of suits against Prozac. California Lawyer also mentions other highly qualified critics of the drug: “David Healy, MD, an internationally renowned psychopharmacologist, has stated in sworn deposition that `contrary to Lilly’s view, there is a plausible cause-and-effect relationship between Prozac’ and suicidal-homicidal events. An epidemiological study published in 1995 by the British Medical Journal also links Prozac to increased suicide risk.”