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Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12

 
NawtyBits
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Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
This is a thread to continue

Thread: >>>EBOLA 2014-15 >> Latest News and Updates for MERS, Ebola and other spreading nasties<<< (Page 1100)

with an OP who is still around. News and thoughtful discussion welcome. I don't have the time or inclination to suffer fools, idiots, or trolls.

h/t monotreme

WHO preparing for worst-case Ebola scenario

[link to www.cnn.com (secure)]

Meera Senthilingam and Debra Goldschmidt, May 11, 2018

The World Health Organization is preparing for the "worst-case scenario" as it continues to respond to the Ebola outbreak in the Democratic Republic of Congo.

Peter Salama, deputy director-general of emergency preparedness and response at the WHO, said in Geneva, Switzerland, on Friday that it's "going to be tough and it's going to be costly to stamp out this outbreak."
There have been 34 cases of Ebola virus disease reported during the past five weeks, the WHO said Friday. Of those, two have been confirmed using laboratory tests, 14 are suspected, and 18 -- who are deceased -- are considered probable for the disease. Three of the patients are health care workers.

"The number of suspected, probable and confirmed cases is significant, so we are very concerned, and we are planning for all scenarios, including the worst-case scenario,"
Salama said.

Comment: WHO got caught with it's pants down with the last outbreak. At least they are trying to get in front of this one.

Last Edited by NawtyBits on 12/11/2018 08:34 AM
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
h/t Monotreme:

Hoping to head off an epidemic, Congo turns to experimental Ebola vaccine

[link to www.sciencemag.org]

Jon Cohen May 15, 2018

The first ever effort to use a vaccine to stop an Ebola outbreak in its initial stages is taking shape in the Democratic Republic of the Congo (DRC). The international response to health emergencies in sub-Saharan Africa is often maddeningly slow. But this time around, international agencies and the DRC government sprang into action, hoping to quickly extinguish the outbreak.

“Everything is organized,” says virologist Yap Boum, who works with Doctors Without Borders (MSF) and is helping launch the vaccine effort. Boum, who lives in Yaoundé, Cameroon, began planning his trip to the DRC as soon as it confirmed on 8 May that two Ebola cases had occurred in the remote Bikoro health district in the Équateur province.

By tracing contacts between the infected people and others who had Ebola symptoms, such as high fevers and diarrhea, the DRC’s Ministry of Public Health (MOPH) determined that the virus has likely been spreading since early April. As Science went to press, a total of 25 other probable cases and 14 suspected ones had been identified in Bikoro and two adjacent health districts. Nineteen of these people have died.

Boum says the most alarming news from the DRC so far is that two of the probable cases are in Mbandaka, a port city of 1.2 million people. “The possibility of the virus spreading is huge,” adds Boum, noting that while Ebola is incubating undetected—which can take several weeks—the victim is already infectious. DRC President Joseph Kabila has authorized MOPH to use every tool at its disposal, including the experimental vaccine against Ebola, which worked spectacularly well in a clinical trial that Boum helped run in Guinea in 2015 at the tail end of the recent West African epidemic.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
h/t Monotreme

AP Explains: Ebola reaches an urban area in Congo. What now?

[link to www.washingtonpost.com (secure)]

Cara Anna&#8201;|&#8201;May 17
The global health community gulped Thursday with the announcement that a case of Ebola had been confirmed in a city of more than 1 million
in Congo, bringing the latest outbreak of the often deadly hemorrhagic fever out of remote rural areas. “Confirmation of urban #Ebola in #DRC is a game changer in this outbreak - the challenge just got much much tougher,” the World Health Organization’s emergencies chief, Dr. Peter Salama, said on Twitter. Here’s a look at the outbreak.

[snip]

Congo Health Minister Oly Ilunga says he is worried because Mbandaka is densely populated and at the crossroads of Equateur province. The city lies on the Congo River, a crucial travel hub in the vast country where infrastructure is largely poor. Downstream is Congo’s capital, Kinshasa, with a population of roughly 10 million.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
h/t AC73972382

Thread: EBOLA: It has now spread to a city with million inhabitants
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
I'm here as well, It's a port city upstream from the capital. looks like things are going to get serious fast.
Does anyone know about the cultural aspects that caused issues in the last one dealing with things like burial?
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
h/t crofsblog

[link to crofsblogs.typepad.com]

Branswell: WHO to weigh declaration of international emergency over Ebola outbreak
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
h/t crofsblog

[link to crofsblogs.typepad.com]

Branswell: WHO to weigh declaration of international emergency over Ebola outbreak
 Quoting: NawtyBits


This is the Helen Branswell article that crofsblog referenced. Branswell is very reliable when reporting on infectious diseases.

[link to www.statnews.com (secure)]

WHO to weigh declaration of international emergency over Ebola outbreak

By Helen Branswell @HelenBranswell

May 17, 2018

The World Health Organization has convened a special committee of experts to help guide its response to the expanding Ebola outbreak in the Democratic Republic of the Congo. During its first meeting on Friday, the group will be asked if the outbreak should be declared an international health emergency.

Comment: Tomorrow. The WHO is not messing around this time.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Not good news for sure.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
[link to www.promedmail.org]

Communicated by:
ProMED-mail Rapporteur Mary Marshall

[Mbandaka is a port city of 1.2 million people. "The possibility of the virus spreading is huge," says virologist Yap Boum, who works with Doctors Without Borders (MSF) noting that while Ebola is incubating undetected--which can take several weeks--the victim is already infectious. - Mod LK]



*************************************



Date: Tue 15 May 2018
Source: Focus Taiwan [edited]
[link to focustaiwan.tw]


Taiwan's Centers for Disease Control (CDC) on [Tue 15 May 2017] issued a travel warning for the Democratic Republic of Congo, citing a new outbreak of the Ebola virus there.

In its Level 2 travel advisory, the CDC cautioned against travel to the affected areas and urged people to stay away from wildlife if such visits cannot be avoided and to take preventative measures against infection. ...



**************************************



[link to www.mediacongo.net]


Gabon, where Ebola has already arisen many times and killed many people in the past, has taken seriously the threat of a possible spread of the epidemic from the DRC. The country has decided to reactivate its Ebola Response Committee to be ready. ...-more



***************************************


Date: Tue 15 May 2018
Source: This Day Live [edited]

[link to www.thisdaylive.com (secure)]


The Nigerian Civil Aviation Authority (NCAA) has directed Nigerian airlines, especially those operating international and regional destinations, to be vigilant in the screening of passengers before they are allowed to board flights to the country. This is aimed at preventing travellers who have Ebola Virus Disease (EVD) from coming to Nigeria.



*******************************************



Source: Media Congo [in French, machine trans., edited]

[link to www.mediacongo.net]


The epidemic of Ebola presents risks, according to the WHO representative in the Congo, Dr. Fatoumata Binta Diallo, for some departments of the Congo. -Brazzaville and some countries in the region.

"The epidemic has erupted in Equateur; the localities of Mbandaka and Bikoro are very close to the Likouala department, specifically the city of Liranga. As such, the WHO has declared some countries at very high risk. These are the Congo, the Central African Republic, all those countries that are bordering the DRC and especially this area [Congo]. We are on full alert, we are already in a position to prepare and respond quickly,..."she said.

The Equateur region in the DRC is bordering the department of Likouala. The 2 regions, whose populations exchange daily, are separated by the Ubangi River which leads to the Central African Republic.

[snip]

Communicated by:
ProMED-mail Rapporteur Mary Marshall

[Bikoro is in a very remote area of a country that has poor road infrastructure; it is situated on a lake connecting the highly trafficked Congo and Ubangi rivers. From there, people infected with Ebola can hop boats to major cities like the DRC's capital Kinshasa or nearby Brazzaville -- a potential public health nightmare officials are trying to prevent quickly.

Brazzaville, city (commune), capital, and river port of the Republic of the Congo and former capital of French Equatorial Africa, is situated on the north bank of the Congo River below Malebo (Stanley) Pool, across from Kinshasa, capital of the Democratic Republic of the Congo. Its population is estimated to exceed 1.8 million. Over a third of the population of the Republic of Congo lives in the capital.

[A HealthMap/ProMED-mail map can be accessed at: [link to healthmap.org] - Mod.LK]
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
[link to virologydownunder.com]

New Ebola virus disease case confirmed in a third DRC health zone

Posted onMay 17, 2018

The Democratic Republic of the Congo (DRC) Ministry of Health (MOH) today announced that 1 of 2 suspected EVD cases in the Wangata Health Zone has tested positive for Ebola virus.

[snip]

This is of particular concern as the case reportedly occurred within Mbandaka, the capital of Équateur province and a city of approximately 1 million people.[2]

MSF maps [9] show the city of Mbandaka sitting in the Mbandaka Health Zone, not the Wangata Health Zone so someone is a bit confused.

Now is certainly a good time to have the experimental Ebola virus vaccine (V920) onsite and ready to be distributed to healthcare workers and contacts of cases in a ring vaccination format. This approach encircles cases with vaccinated people to prevent further spread from known foci of infection.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Not good news for sure.
 Quoting: Treyfish 73694037


Hey Trey,

Long time. Hope you are well.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Are they using the Russian phage based vaccine?

or the American vaccine?
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Is WAKANDA safe?
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
[link to news.osu.edu (secure)]

New pig virus found to be a potential threat to humans

COLUMBUS, Ohio – A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health.

Researchers at The Ohio State University and Utrecht University in the Netherlands collaborated to better understand the new virus and its potential reach. Their study, the first to point to possible transmission of this virus between species, appears online in the journal PNAS.

Porcine deltacoronavirus was first identified in 2012 in pigs in China, but it was not associated with disease. It was first detected in the United States in 2014 during a diarrhea outbreak in Ohio pigs and has since been detected in various countries. Young, infected pigs experience acute diarrhea and vomiting. The disease can be fatal. As of yet, no human cases have been documented, but scientists are concerned about the possibility.

Comment: Other coronaviruses include MERS and SARS.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Are they using the Russian phage based vaccine?

or the American vaccine?
 Quoting: Anonymous Coward 74051736



[link to www.npr.org (secure)]


[Summary of key points on vaccine from report. - Mod LK]
Vaccine, rVSV-ZEBOV, first tested in 2015 in the waning months of the massive Ebola epidemic in West Africa. Ira Longini, a biostatistician at the University of Florida who helped run that trial, notes that 7500 people were given the vaccine.

A total of 4000 doses of the vaccine have been shipped to the DRC -- with another 4000 to follow soon. The World Health Organization is coordinating the vaccination effort.

[snip]

Vaccine is still awaiting licensing, so governments need to give special permission for it to be used. Merck, which produces the vaccine, will be donating it. Gavi, the Vaccine Alliance, the British-based charity the Wellcome Trust, and the British government have jointly contributed $4 million to carry out the campaign.

Comment: That's the best info I can find so far.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
I'm here as well, It's a port city upstream from the capital. looks like things are going to get serious fast.
Does anyone know about the cultural aspects that caused issues in the last one dealing with things like burial?
 Quoting: Feistylorax


You mean like hand washing the dead body as part of the funeral process?
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Are they using the Russian phage based vaccine?

or the American vaccine?
 Quoting: Anonymous Coward 74051736



[link to www.npr.org (secure)]


[Summary of key points on vaccine from report. - Mod LK]
Vaccine, rVSV-ZEBOV, first tested in 2015 in the waning months of the massive Ebola epidemic in West Africa. Ira Longini, a biostatistician at the University of Florida who helped run that trial, notes that 7500 people were given the vaccine.

A total of 4000 doses of the vaccine have been shipped to the DRC -- with another 4000 to follow soon. The World Health Organization is coordinating the vaccination effort.

[snip]

Vaccine is still awaiting licensing, so governments need to give special permission for it to be used. Merck, which produces the vaccine, will be donating it. Gavi, the Vaccine Alliance, the British-based charity the Wellcome Trust, and the British government have jointly contributed $4 million to carry out the campaign.

Comment: That's the best info I can find so far.
 Quoting: NawtyBits


we need the russian phage based vaccine

america vaccine is garbage.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Are they using the Russian phage based vaccine?

or the American vaccine?
 Quoting: Anonymous Coward 74051736



[link to www.npr.org (secure)]


[Summary of key points on vaccine from report. - Mod LK]
Vaccine, rVSV-ZEBOV, first tested in 2015 in the waning months of the massive Ebola epidemic in West Africa. Ira Longini, a biostatistician at the University of Florida who helped run that trial, notes that 7500 people were given the vaccine.

A total of 4000 doses of the vaccine have been shipped to the DRC -- with another 4000 to follow soon. The World Health Organization is coordinating the vaccination effort.

[snip]

Vaccine is still awaiting licensing, so governments need to give special permission for it to be used. Merck, which produces the vaccine, will be donating it. Gavi, the Vaccine Alliance, the British-based charity the Wellcome Trust, and the British government have jointly contributed $4 million to carry out the campaign.

Comment: That's the best info I can find so far.
 Quoting: NawtyBits


we need the russian phage based vaccine

america vaccine is garbage.
 Quoting: Anonymous Coward 74051736


It won't matter. 8,000 doses of anything will be like pissing on a forest fire.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Thanks for starting a new thread. Hope it isn't too much to handle, with the pile-on of hoaxers and trolls likely to visit.

It's what they aren't saying about this outbreak that has me concerned. Unlike the last one, this is virtually D-Listed.

Let's hope it doesn't create a stampede down the road.
"I would rather take a political risk in pursuit of peace, than risk peace in pursuit of politics." - Donald Trump
Crazy Harriet

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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
I'm here as well, It's a port city upstream from the capital. looks like things are going to get serious fast.
Does anyone know about the cultural aspects that caused issues in the last one dealing with things like burial?
 Quoting: Feistylorax


You mean like hand washing the dead body as part of the funeral process?
 Quoting: NawtyBits


Yea, we covered this in detail. Read that last thread which is linked on the OP here. You'll know more than you ever wanted to know about housing, food, cultural practices and weather where Ebola thrives.
"I would rather take a political risk in pursuit of peace, than risk peace in pursuit of politics." - Donald Trump
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
Anonymous Coward
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Just saw this article , it's in French, saying that 300 people potentially had direct or indirect contact with the infected (which were all regularly going to church). It also says that people in the city are starting to panick.
Anonymous Coward
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Sorry I forgot to link the article :
[link to www.google.fr (secure)]
Anonymous Coward
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
 Quoting: Anonymous Coward 76588029


Bring it on.

We're atleast 5 billion too many, and we've gone fubar on the entire planet.
Anonymous Coward
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
 Quoting: Anonymous Coward 76588029


Bring it on.

We're atleast 5 billion too many, and we've gone fubar on the entire planet.
 Quoting: Anonymous Coward 76566622


Then we should start with you right now.
MissCleo

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05/17/2018 01:25 PM

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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
Madagascar Plague fizzled out after threats to the tourism industry there.

I believe these pandemics happen every year during this season, and it's a spin of the wheel if there are massive casualties.

The problem happens when infected people leave, or terrorists smuggle infection, or the disease breaks out to a new city.
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
 Quoting: Anonymous Coward 76588029


Bring it on.

We're atleast 5 billion too many, and we've gone fubar on the entire planet.
 Quoting: Anonymous Coward 76566622


Then we should start with you right now.
 Quoting: Anonymous Coward 49476107


We were only 3.5 billion when I was born. I never reproduced, and I live deep in the Scandinavian forests far the fuck away from cities. And systemic human stupidity and general mayhem.

The ebola will most likely pass me by. Death will not.

But for those who chose to reproduce, live and organise themselves in mega-cities, while we kill off the last rhino's and lions and smother the planet...

Nature has a way to deal with species in overshoot. Several, actually. Plagues and epidemics is just one.

I have no problem with that.

Life is cheap, after all. Mine and yours too. Always was.
Anonymous Coward
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Re: Going Viral-Ebola vaccine is having ‘major impact’ but Congo outbreak may still explode; pg12
It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
 Quoting: Anonymous Coward 76588029


Bring it on.

We're atleast 5 billion too many, and we've gone fubar on the entire planet.
 Quoting: Anonymous Coward 76566622



Hello Thanos
Anonymous Coward
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It looks very bad... Very populated area and directly linked to Kinshasa (17 millions inhabitants) and Kisangani (1 million inhabitants) by the river. :/
 Quoting: Anonymous Coward 76588029


Bring it on.

We're atleast 5 billion too many, and we've gone fubar on the entire planet.
 Quoting: Anonymous Coward 76566622


yeah but how will the earth survive without 17 million black muslims?
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DRC: Ebola outbreak enters 'new phase' after urban case confirmed

'Game changer' as Ebola outbreak hits urban centre in Democratic Republic of Congo.
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"We are entering a new phase of the Ebola outbreak that is now affecting three health zones, including an urban health zone," Ilunga said in a statement.