Thread to gather our great medical, chem, lab, molecule minds and geniuses. Please check in. Amazing update.

Oh i don't need to "believe" what I have seen with my eyes and held in my hands.

I once treated a degloved (skin torn off) leg with wet silver dressings and fed em reishi and turkey tail.
Guess what grew back pretty and new, hair folicles and all, like it had never been hurt? Pretty grateful to God there.
Another time some people fled with thier baby, running from a forced skin graft. He was 2 and fell and put his hand on the wood stove. The hospital was going to sieze the baby and do the surgery to get the surgeon and hospital massive gov money.
They fled to the monastery with him hoping we could do anything but that.
Guess who else you can not tell was ever burnt? Another thank you God.
Both of those are true stories of what amazed me as a physician and both were done with nothing more than people could do for thier selves at home.

We got "convenia"'d off gaurd. The helpers are like you - wouldn't know if it was crazy, lethal or not? Believed the vet.
He was a mess for days and i had words with the other "dr" about burning up our resident. Treated him like an antibiotic overdose + vaxx reaction and to prevent autism. He recoverd but it was horrific what they did. So heartbreaking. Hell is not horrible enough for some of these bastar*s.

(When hell breaks loose here, my interpreter will tell the savages who the drs, nurses and vets we have identified as abusers and snuffers are and let them be hells angels. We would only catch ones snuffing vets, old people or peoples pets, so they are all true bastar*s with it fully coming. Hondurans are good for that.)

I have a lot to offer in terms of knowledge of all opiate RC's and traditional medicines.

Thank you, Post some links and do share, many are suffering needlessly.

for later

Hey OP, can you provide a concise step by step instruction in one post?

1. Buy this stuff
2. Buy this other stuff.
3. Mix the stuffs together in this quantities.
4. Shake this long for this many weeks.
5. Mix with this stuff.
6 Drink this much per day.

Your instructions in this post are a bit schizophrenic. Not intended to be a insult, jst hard to follow your instructions. Thanks.

This is what is working for me. I am not saying it can not be improved or varied. I do not know why or how it is working for sure.

For my wight of 130 lbs I use...

One teaspoon of C60 oil first thing in the morning on an empty stomach in my morning coffee, with milk and sugar.

30 mg of Noopept in the morning an hour or two after the C60 has had time to digest.

50 mg of DMAE mixed in one quart of water consumed over time, the first half of the day.

I have also posted about my regular diet in case that has had an unknown reaction to aid with the c60, dmae and noopept on my healing, my diet did not aid in my healing much before. I think lemon juice helps in an unusual way and be sure to drink lots of water.

How I make my own affordable C60 oil...

One gram of tested quality pure C60 crushed to as fine of powder as possible {I use %99.95 because I can not afford %99.99} added to one pint jar of pure unrefined coconut oil, kept liquid around 75 F, Keep wrapped up and protected from all light, gently shake as often as possible, a few times an hour for 3 to 5 weeks depending on how often you shake it and the size of the particles, until it is dispersed. Allow to settle out, a day or two so any heavy particle sink, pour off the majority, leaving the heavy solution at the bottom to start your next batch.

The most important thing is to get good quality tested real Fullerenes C60, 99.9 % to 99.99 not low grade or charcoal being passed off for c60 or say it is tested when it is was not and not the true stuff. I found the best price was cheaptubes.com and it is tested. It is half the price as others with the same quality. The price is going up for everyone and in high demand, not in stock is normal right now, request to be put on a waiting list for the next shipment.
Where I get mine, if a new order does not test out good enough, they send it back and I wait even longer for the next shipment. Well worth the wait.

Do not consume C60 particles, only the oil.

I have stated many times, I am no expert.
This is a new uncharted experimental treatment, just my experience of using my body as a test rat, nothing concise.

This is a thread asking for help from scientific minds to figure it out so we can help others in need of healing and relief from sever pain.

Hello OP I love this thread cant wait to get going on this. I have one question once the c60 oil has been poured off you say you are using the sediment for the next batch as one should not consume the powder only the oil.My question is how many batches of oil does the original crushed c60 make before you need to start with new c60 TY

You start the next batch with another gram of C60, refill with more coconut oil, and start over.

Two days ago I burned my palm and fingers pretty bad catching a near red hot metal pan I dropped. I did not want to burn my new flooring. It hurt so bad I had to sleep with my hand in a bowl of cold water. The next morning there was no sign of any burn, no pain, no blister, not even a red mark, just a little tender and mild sting in hot water. I was sure I was going to have down time unable to use my hand.

I really appreciate the attitude of trying things out on yourself and experimenting to see what works and what doesn't.

That's how I try to be and it's encouraging to see others taking that point of view too.

Please

I am pretty sure I have posted everything I have been doing.

I am the OP,

Anyone want to help research Lutien and other things to help aging eyes? I am seeking to improve vision with nootropic molecules.

This thread gives a little insight on how this works.

Thread: INFO!!! WANT to SLOW the AGING PROCESS??? BETA ALANINE and HISTIDINE MAKE CARNOSINE!!! EXTEND YOU'RE TELOMERES!!! (Page 5)

Today I added the nootropic Husperzine A to my daily routine to see if it helps with my vision. I am still researching, this is just a test.
I have had a little improvement in vision the last few months but as much as I need and not very fast.

Now that there is a bit of interest in this thread I will share some research gems. I have tried Hup A in the past but it was too strong for me and I let it sit. I am working out the bugs and giving it another go for many reasons. It was too much time and work to go back and find all my old research to post and most would not read it anyway.

[link to www.ncbi.nlm.nih.gov (secure)]


Huperzine A attenuates mitochondrial dysfunction in beta-amyloid-treated PC12 cells by reducing oxygen free radicals accumulation and improving mitochondrial energy metabolism.
Gao X1, Tang XC.
Author information
Abstract
We observed previously that huperzine A (HupA), a selective acetylcholinesterase inhibitor, can counteract neuronal apoptosis and cell damage induced by several neurotoxic substances, and that this neuroprotective action somehow involves the mitochondria. We investigated the ability of HupA to reduce mitochondrial dysfunction in neuron-like rat pheochromocytoma (PC12) cells exposed in culture to the amyloid beta-peptide fragment 25-35 (Abeta(25-35)). After exposure to 1 microM Abeta(25-35) for various periods, cells exhibited a rapid decline of ATP levels and obvious disruption of mitochondrial membrane homeostasis and integrity as determined by characteristic morphologic alterations, reduced membrane potential, and decreased activity of ion transport proteins. In addition, Abeta(25-35) treatment also led to inhibition of key enzyme activities in the electron transport chain and the tricarboxylic acid cycle, as well as an increase of intracellular reactive oxygen species (ROS). Pre-incubation with HupA for 2 hr not only attenuated these signs of cellular stress caused by Abeta, but also enhanced ATP concentration and decreased ROS accumulation in unharmed normal cells. Those results indicate that HupA protects mitochondria against Abeta-induced damages, at least in part by inhibiting oxidative stress and improving energy metabolism, and that these protective effects reduce the apoptosis of neuronal cells exposed to this toxic peptide.

2006 Wiley-Liss, Inc.

This could be a missing part of my formula to help restore vision. HupA is a bit a repeat of DMAE but with other aspects.

[link to www.ncbi.nlm.nih.gov (secure)]
The anti-inflamm-aging and hepatoprotective effects of huperzine A in D-galactose-treated rats.
Ruan Q1, Liu F, Gao Z, Kong D, Hu X, Shi D, Bao Z, Yu Z.
Author information
Abstract
Oxidative stress contributes to a chronic inflammatory process referred to as "inflamm-aging". Acetylcholinesterase inhibitors (AChEI) can enhance cholinergic transmission and act as anti-inflammatory agents via immunocompetent cells expressing α-7 acetylcholine receptors (AChR). The present study explores the possible role of huperzine A, a reversible and selective AChEI, against D-gal-induced oxidative damage, cell toxicity and inflamm-aging in rat livers. In two-month-old rats with normal liver function, an 8-week administration of D-gal (300 mg/kg subcutaneously (s.c.) injected), significantly increased hepatic impairment, ROS generation and oxidative damage, hepatic senescence, nuclear factor-kappa B (NF-κB) activation and inflammatory responses. An 8-week co-administration of both D-gal (300 mg/kg s.c.) and huperzine A (0.1 mg/kg s.c.) not only significantly decreased hepatic function impairment, ROS generation, oxidative damage, but also suppressed inflamm-aging by inhibiting hepatic replicative senescence, AChE activity, IκBα degradation, NF-κB p65 nuclear translocation and inflammatory responses. The expression levels of pro-inflammatory cytokine mRNA and proteins, such as TNFα, IL-1β and IL-6 decrease significantly, and the protein levels of the anti-inflammatory cytokine IL-10 display an obvious increase. These findings indicated that D-gal-induced hepatic injury and inflamm-aging in the rat liver was associated with the development of a pro-inflammatory phenotype in this organ. D-gal induced damage-associated molecular patterns (DAMPs) because oxidative damages might play an important role in D-gal-induced hepatic sterile inflammation. Huperzine A exhibited protective effects against D-gal-induced hepatotoxicity and inflamm-aging by inhibiting AChE activity and via the activation of the cholinergic anti-inflammatory pathway. The huperzine A mechanism might be involved in the inhibition of DAMPs-mediated NF-κB nuclear localization and activation.

Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A
Dou Yu,a,b,1 Devang K. Thakor,a,b,1 Inbo Han,a,b Alexander E. Ropper,a,b Hariprakash Haragopal,a,b Richard L. Sidman,c,2 Ross Zafonte,d Steven C. Schachter,c,e and Yang D. Tenga,b,d,2
Author information Copyright and License information Disclaimer
See "PNAS Plus Significance Statements" in volume 110 on page 2699.
This article has been cited by other articles in PMC.
Go to:
SIGNIFICANCE
Neuropathic pain, one of the most debilitating sequelae of neurotrauma, is an unmet clinical need for at least 40% of patients with spinal cord injury (SCI). We demonstrate that [-]-huperzine A (HUP-A), a naturally occurring Lycopodium alkaloid isolated from the Chinese club moss, Huperzia serrata, with potent reversible inhibitory action on acetylcholinesterase and N-methyl-d-aspartate glutamate receptors, offers an exceptional prospect for multimodal treatment of SCI-induced neuropathic pain in rats. HUP-A restores homeostasis of central sensory neurocircuitry without invoking drug tolerance and dependence or respiratory suppression. We therefore conclude that multimodal actions provide a fresh translational approach to reduce chronic pain.

Keywords: botanical medicine, hyperalgesia
Go to:
ABSTRACT
Diverse mechanisms including activation of NMDA receptors, microglial activation, reactive astrogliosis, loss of descending inhibition, and spasticity are responsible for ∼40% of cases of intractable neuropathic pain after spinal cord injury (SCI). Because conventional treatments blocking individual mechanisms elicit only short-term effectiveness, a multimodal approach with simultaneous actions against major pain-related pathways may have value for clinical management of chronic pain. We hypothesize that [-]-huperzine A (HUP-A), an alkaloid isolated from the club moss Huperzia serrata, that is a potent reversible inhibitor of acetylcholinesterase and NMDA receptors, could mitigate pain without invoking drug tolerance or dependence by stimulating cholinergic interneurons to impede pain signaling, inhibiting inflammation via microglial cholinergic activation, and blocking NMDA-mediated central hypersensitization. We tested our hypothesis by administering HUP-A i.p. or intrathecally to female Sprague–Dawley rats (200–235 g body weight) after moderate static compression (35 g for 5 min) of T10 spinal cord. Compared with controls, HUP-A treatment demonstrates significant analgesic effects in both regimens. SCI rats manifested no drug tolerance following repeated bolus i.p. or chronic intrathecal HUP-A dosing. The pain-ameliorating effect of HUP-A is cholinergic dependent. Relative to vehicle treatment, HUP-A administration also reduced neural inflammation, retained higher numbers of calcium-impermeable GluR2-containing AMPA receptors, and prevented Homer1a up-regulation in dorsal horn sensory neurons. Therefore, HUP-A may provide safe and effective management for chronic postneurotrauma pain by reestablishing homeostasis of sensory circuits.

Neuropathic pain is one of the most debilitating sequelae of neurotrauma and is an unmet clinical need for at least 40% of patients with spinal cord injury (SCI) (1). Administration of conventional drugs has shown only various degrees of short-term efficacy in reducing at- and/or below-injury-level hypersensitivity after SCI by acting on individual pathways to inhibit descending facilitation of pain-transmission neurons (2), activate inhibitory interneurons in the spinal cord (2, 3), mitigate firing of pain-transmission neurons (3–7), or impede inflammation triggered by the activation of astrocytes and microglial cells (8). The diversity of mechanisms and potential targets for intervention may be partially responsible for the difficulty in developing therapeutics that can provide long-term efficacy. Therefore we postulated that devising a multimodal treatment with potent, defined simultaneous effects on multiple pain-related pathways might be an effective concept for clinical management of neuropathic pain.

Given the potential roles of cholinergic agonists (9, 10) and antagonists of NMDA-subtype glutamate receptors (10, 11) in the treatment of neuropathic pain, we hypothesized that [-]-huperzine A (HUP-A) (Fig. 1A), a naturally occurring Lycopodium alkaloid isolated from the Chinese club moss, Huperzia serrata (Fig. 1B) that has potent reversible inhibitory action on acetylcholinesterase (AChE) (Fig. 1C) (10, 12) and NMDA receptors (Fig. 1D) (13), might be an exceptional prospect for multimodal treatment of SCI-induced neuropathic pain. We tested whether HUP-A–derived NMDA blockade and the overall HUP-A–derived augmentation of cholinergic neurotransmission arising from AChE inhibition might be harnessed specifically to stage a multifocal intervention in post-SCI pain pathways because (i) antagonism of NMDA receptor prevents the post-SCI hyperexcitability of neurons in the dorsal horn (DH) of the spinal cord that feature a wide, dynamic range of pain transmission (7); (ii) activation of presynaptic α3β2 nicotinic ACh receptors (nAChR) minimizes release of glutamate from C-fiber terminals in the DH that are involved in nociceptive neurotransmission (14); (iii) activation of GABAergic interneurons via stimulation of their M2 and M4 muscarinic ACh receptors (mAChR), in turn, inhibits presynaptic release of glutamate from primary afferent axons (15, 16); (iv) activation of the α4β2 nAChR on GABAergic inhibitory interneurons mitigates the firing of secondary spinothalamic pain transmission neurons (17); and (v) stimulation of the α7 nAChR on microglial cells blocks their activation, ameliorating neuroinflammation (18, 19). The primary goal of our study is to develop a class of therapeutics for the management of chronic neuropathic pain that aims to restore homeostasis of the sensory neurocircuitry by simultaneous multimodal mechanisms without invoking drug tolerance and dependence or respiratory suppression. HUP-A has been used for centuries in herbal medicine to treat inflammatory and other diseases (10, 12), has demonstrated effectiveness in inhibiting hypersensitivity triggered by peripheral neuropathy (20), and has been studied in phase II clinical trials for Alzheimer’s disease in the United States (11). We tested whether HUP-A regimens might translate into an effective and safe therapy for neuropathic pain following SCI in adult female rats (21–23).

MORE AT THE LINK [link to www.ncbi.nlm.nih.gov (secure)]

Update.... Undesired muscle bulk. I am a small female and have worked very hard my entire life, hard labor and have good firm lean muscle tone, not bulky muscles. Less than a week of some outdoor work as the snow is hardly half melted and I am bulking up, raised up protruding muscles that feel tender. I am a bit worried what I will look like by the end of the hard work season.

And I have never craved protein and fat like this before, whole milk, butter, red meat and beans. If I do not have these, it feels like I did not eat at all and have to make and eat another meal. I was mostly fruit, veggie, legume, nuts and whole grain diet before.

Ceramides will be my next suppliment when I can afford it. Basically put, isolated condensed food food for the skin and tissue. [link to www.ncbi.nlm.nih.gov (secure)]

If I can not afford natural sources, I will try synthetic form of Ceramides. I am now no longer opposed to synthetics, I have found they often work better, faster with less adverse side effects from other compounds in some products.

When you guys post try this and that food or plant etc, do a research into the active component, ingredient, molecule that is producing the positive result. You will find that active ingredient can be found in other sources as well but these sources can have unwanted counteracting ingredients with unwanted side effects. So processed, condensed, isolated or synthis can be a major advantage.

I can understand that bulking up with muscle would freak you out, but for the work you're doing it sounds helpful? And you must be in tune with your body for you to be listening to your craving for protein and fats that you need to build muscle and work hard.

Maybe go with it for a little while and see if your body adjusts to this new healthy state and adjusts the muscle tone?

Maybe some topical estrogen would help? Are you getting unwanted hair anywhere on your face?

Is any of the stuff you've been doing hormonal, like DHEA, pregnenolone, progesterone, etc.?

Man I loved how I felt when I took a low dose of DHEA and pregnenolone, but after a little while it backfires and I got really anxious and crabby, plus I didn't like the unwanted hair. But I had the energy and attitude of a teenager! energy through the roof, bouncing out of bed, fresh and ready to face the day!

I still take the pregnenolone sometimes but I think it's too much with the progesterone topical together and I think I need the progesterone topical.

I am not a doctor and nothing I have ever said on this site or anywhere else is intended to substitute for qualified medical care.

This is an interesting example. Take a look a the different chain structures of phytoceramides and the combined. [link to www.ncbi.nlm.nih.gov (secure)]

I have always had a lot of muscle working construction, farming etc. Having them stick out is not good LOL.

I do not take any hormones. I was pleased to be free of hormonal behavior after the change. I did try / tested individually DHEA, Mucana, and Melitonin not long ago and had very bad results. I will not take it again with the other stuff I am taking. I had a bad reaction and will not take that again with the C60.

Some things the C60 makes work better, some a bad reaction and some it just voids, eliminates.