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2019-nCov: SARS with HIV sequences?

 
Anonymous Coward
User ID: 78235801
Canada
01/31/2020 04:35 PM
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2019-nCov: SARS with HIV sequences?
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"Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on the evolution and pathogenicity of this virus with important implications for diagnosis of this virus. "

TL;DR: Virus has seemingly unlikely to appear in nature connections to HIV genetic sequences.
Anonymous Coward (OP)
User ID: 78235801
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01/31/2020 04:36 PM
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Re: 2019-nCov: SARS with HIV sequences?
[link to biorxiv-cache.s3-us-west-2.amazonaws.com (secure)]
Anonymous Coward
User ID: 75953087
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01/31/2020 04:37 PM
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Re: 2019-nCov: SARS with HIV sequences?
So its probably a bioweapon leak and not from that animal market.





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