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COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)

 
Anonymous Coward
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04/24/2020 01:07 PM
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COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
No dubious vaccines needed, folks.

The old practice of 'convalescent serum therapy' is being revived. A version of this type of treatment was used a century ago during the Spanish flu of 1918...


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Houston Methodist performs the nation’s first plasma transfusion to treat COVID-19

March 31, 2020

Blood plasma transfusion was used to treat COVID-19 for the first time in the United States by physician-scientists at Houston Methodist Hospital this past weekend.

The U.S. Food and Drug Administration (FDA) fast-tracked an old treatment that doctors hope will fight this new coronavirus successfully enough to flatten the curve sooner than expected to curb mounting fatalities.


After FDA clearance on March 28, 2020, Houston Methodist became the first academic medical center in the country to transfuse donated blood plasma from a fully recovered COVID-19 patient into a critically ill person—a treatment known as convalescent serum therapy. The historic acts occurred when researchers drew a quart of blood plasma from a COVID-19 survivor and transfused two people infected with the virus.


[link to www.tmc.edu]

"There haven’t been … the best controlled trials, but there’s a rich medical history of this," said James Musser M.D., Ph.D., pathology and genomic medicine chair at Houston Methodist Research Institute and Houston Methodist Hospital. "What hasn’t been done—and is important to do at this juncture as fast as we can—is to do a real trial and figure out if this is going to be beneficial at all. If so, is it beneficial a little, a lot or a whole lot?”

Last week, a team of Chinese scientists published a paper in the Journal of the American Medical Association describing the use of convalescent plasma on five patients as potentially helpful for treating critically ill patients with COVID-19. Within three days of transfusion, body temperatures normalized in four of the five patients. Within 12 days, the number of viral particles disappeared, and within two weeks, three patients were taken off mechanical ventilation.


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Antibodies from COVID-19 survivors could be used to treat patients, protect those at risk

Infusions of antibody-laden blood have been used with reported success in prior outbreaks, including the SARS epidemic and the 1918 flu pandemic

[link to hub.jhu.edu]

-------------------------------------------------------------​


2 New Jersey COVID-19 patients recovering after experimental plasma treatment


April 22, 2020

[link to 6abc.com]

"...Renee Bannister, a 63-year-old school teacher, had been on a ventilator for three weeks with no sign of improvement. That's when her doctor decided to look into convalescent plasma therapy. The plasma comes from donors who recently recovered from COVID-19 and subsequently possessed protective antibodies. Fortunately, Renee's niece had recently recovered from a mild case of the virus and offered to be a donor.
...

Bannister's doctor got FDA approval to take part in the Mayo Clinic trial using Leuzzi as a donor.

'The improvement started happening maybe 48 to 72 hours after the plasma transfusion,' said Dr. Polisiakiewicz.


Andy Fei, 61, an opera singer, was also fighting for his life on a ventilator.
...

Doctors say both patients are now off ventilators and making a remarkable recovery.


"We are now giving patients plasma under the umbrella program of the Mayo Clinic," said Dr. Polisiakiewicz.

...

The Red Cross has now set up a bank where doctors in the trial can draw the plasma from. Others who have recovered from the virus are being asked to donate blood hoping to treat more patients with this promising therapy.


rose
Anonymous Coward
User ID: 78800846
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04/24/2020 01:10 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
what kind of idiot would donate for free?


that plasma is worth top dollar right now
Anonymous Coward (OP)
User ID: 78778507
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04/24/2020 01:17 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
For a relative, I definitely would donate.

...I try to donate blood regularly, anyway.

Plasma can be donated every 28 days.


Blood centers will collect plasma from COVID-19 survivors in bid for treatment

April 1, 2020

[link to www.nbcnews.com]

Blood donation centers across the U.S. are ramping up efforts to collect plasma from people who have recovered from COVID-19 in hopes it could be used to save the lives of others infected with the pandemic disease.

Under guidelines released Tuesday by the AABB, an international nonprofit agency focused on transfusion medicine and cellular therapies, dozens of community blood centers nationwide could become a key source for the century-old treatment known as convalescent plasma therapy.
...

A few sites in the U.S., including the New York Blood Center, started collecting plasma last week. And a few clinical trials have started testing the use of survivor plasma for COVID-19. The American Red Cross has set up a website to collect information about potential plasma donors.

...

At community blood centers, plasma will be drawn from donors with lab-confirmed tests showing that they had COVID-19 — and that they’ve since tested negative for it, or that 28 days has passed since they’ve shown symptoms. Donors will be eligible to provide plasma every 28 days, the guidelines say.
Anonymous Coward (OP)
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04/24/2020 01:30 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Have you recovered from COVID?

Consider donating plasma. Learn who the blood supplier is in your region. Many are participating in this trial.

If you have someone specific you would like to donate it to, who currently has COVID, inquire about how to do it!
Anonymous Coward (OP)
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04/24/2020 01:42 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Well, this practice was mentioned over a month ago, here on GLP:


Thread: BLOOD OF THE SURVIVORS: Serum Can Treat Those Suffering
Anonymous Coward (OP)
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04/24/2020 01:58 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
A UMass Memorial COVID Patient Has “Dramatically Improved” After Receiving Hospital’s First Plasma Transfusion

April 22, 2020

[link to www.bostonmagazine.com]

Worcester’s UMass Memorial Medical Center has shared some good news: A critically ill COVID-19 patient saw impressive improvement after receiving the hospital’s first plasma transfusion.

Per a statement from the hospital cited in the Boston Globe on Tuesday, the patient, who was on a ventilator, “dramatically improved” after just hours of transfusion. Before the treatment, the patient needed the ventilator on its maximum settings, and after the transfusion, the patient actually began to be weaned off the device, the statement said.


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Jake

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04/24/2020 01:59 PM
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Yeah no thanks i'm not taking somebody else's blood
Evil controls the ignorant... Climate change is a hoax so is the vax you have been fear-porned into compliance!

Definition Satan from the bible: Satan (Rev 12:7) exercising his subtle (indirect) impact on heathen governments (powers) – i.e. accomplishing his hellish agenda from "behind the scenes."
Anonymous Coward (OP)
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04/24/2020 02:30 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Plasma (serum) also useful as prophylactic.


The convalescent sera option for containing COVID-19


Arturo Casadevall, Liise-anne Pirofski

Published April 1, 2020; First published March 13, 2020
Citation Information: J Clin Invest. 2020;130(4):1545-1548. [link to doi.org (secure)]


[link to www.jci.org]

An individual who is sick with COVID-19 and recovers has blood drawn and screened for virus-neutralizing antibodies. Following identification of those with high titers of neutralizing antibody, serum containing these virus-neutralizing antibodies can be administered in a prophylactic manner to prevent infection in high-risk cases, such as vulnerable individuals with underlying medical conditions, health care providers, and individuals with exposure to confirmed cases of COVID-19. Additionally, convalescent serum could potentially be used in individuals with clinical disease to reduce symptoms and mortality. The efficacy of these approaches is not known, but historical experience suggests that convalescent sera may be more effective in preventing disease than in the treatment of established disease.
Anonymous Coward (OP)
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04/24/2020 05:15 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
'Liquid gold': the rush for plasma and the Covid-19 survivors who want to help

A single Covid-19 survivor can provide enough plasma to treat two or three sick patients. Could it help save lives?

April 16, 2020

[link to www.theguardian.com]


When somebody overcomes an illness, they produce life-saving antibodies – protective blood proteins that ward off antigens, like viruses – and those remain within the blood for a period of time (usually up to three months).

koolaid
Anonymous Coward (OP)
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04/24/2020 05:34 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
As with many blood suppliers, American Red Cross Blood Services is recruiting former COVID patients...

Need a prior, verified diagnosis of COVID-19.

In coordination with the U.S. Food and Drug Administration (FDA), the Red Cross is seeking people who are fully recovered from the new coronavirus to sign up to donate plasma to help current COVID-19 patients.

People who have fully recovered from COVID-19 have antibodies in their plasma that can attack the virus. This convalescent plasma is being evaluated as treatment for patients with serious or immediately life-threatening COVID-19 infections, or those judged by a healthcare provider to be at high risk of progression to severe or life-threatening disease.


Plasma donation takes only about 1.25 hours.
Buzzle

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04/24/2020 05:42 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Considering kids seem to have much milder cases, I'm surprised they're not asking for our kids' blood.
Anonymous Coward
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04/24/2020 06:26 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Still falling for the MSM BS ? bsflag
Anonymous Coward (OP)
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04/24/2020 06:33 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Please.

MSM is promoting wasting billions and sickening us with pharma/elite-backed vaccines.

This is a simple, 100-year-old therapy.
Anonymous Coward (OP)
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04/24/2020 08:00 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
In Delaware, COVID survivors are initially being allowed to donate plasma once a week.

One donation can potentially help three to four people.

Delaware patients now receiving experimental convalescent plasma treatment for COVID-19

April 24, 2020

[link to www.delawareonline.com]
Anonymous Coward (OP)
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04/24/2020 08:16 PM
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Orlando dad, COVID-19 patient, returns home 12 days after receiving plasma from coronavirus survivor

April 21, 2020

[link to www.orlandosentinel.com]


On April 4, Rathel began showing severe symptoms of COVID-19. He was then put on a ventilator and into a medically induced coma.

Stacie asked doctors to try plasma therapy after reading about it online. She then turned to Facebook to find a possible donor.
Anonymous Coward (OP)
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04/24/2020 08:58 PM
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Re: COVID patients cured with plasma/serum donations from those who have recovered from COVID (= antibodies)
Pennsylvania man, aged 74, recovers with plasma


Plasma transfusion that saved Phillipsburg man holds promise in treating critically ill coronavirus patients

April 23, 2020

[link to www.mcall.com]


20 days on ventilator. Then two days after plasma transfusion, he is taken off ventilator.

The ideal protocol for this treatment is not yet known, and some people are not helped by it.


There are still a lot of questions surrounding the use of plasma to treat COVID-19, said Dr. Timothy Friel, an infectious disease specialist with LVHN.

“What is the appropriate dose? When in the course of their illness do they get it? Do you save it for the sickest people who are intubated and on the ventilator? Do you give it earlier in the disease?” Friel said. As of Monday, LVHN had treated five patients with plasma and another 12 were on the waiting list.

Some of those patients improved while others got worse despite the treatment, Friel said. Not all of them were on ventilators.

...Plasma typically is administered intravenously by a single infusion over the course of an hour. Because of the limited supply, there’s no possibility of repeat dosing, and none of the protocols recommend repeat dosing anyway, Friel said.





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