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Accidental discovery leads to Parkinson’s disease cure in mice

 
Anonymous Coward
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06/29/2020 08:27 AM
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Accidental discovery leads to Parkinson’s disease cure in mice
Great news... these scientist figured out how to turn fibroblasts into neurons.

SAN DIEGO – Sometimes, scientific breakthroughs occur when researchers aren’t exactly looking for them. While attempting to better understand the function of a protein in connective tissue cells, UC San Diego School of Medicine scientists found a way to transform multiple types of cells into neurons. This discovery has led to the development of a treatment that eliminates symptoms of Parkinson’s disease in mice.

The protein researchers were studying, called PTB, is known for its general role in activating or deactivating genes within a cell. In an attempt to better understand how PTB contributes to cell function, researchers silenced the PTB gene using a technique called siRNA in a type of connective tissue cell, known as a fibroblast. The researchers grew the fibroblasts in petri dishes, silenced PTB, and waited a couple of weeks to check on the fibroblasts and observe any changes.

When the researchers checked the fibroblasts, they were shocked. They found that very few fibroblasts remained in the dishes. Instead, the dishes contained mostly neurons. Unintentionally, they had discovered a way to turn fibroblasts into neurons.


[link to www.studyfinds.org (secure)]
Funney
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06/29/2020 11:24 AM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
That is a huge discovery!
Anonymous Coward
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06/29/2020 11:32 AM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
Jesus, they should start trying it on patients immediately and give away the treatment free, that is one heinous disease.
Red Hot Chilean Pepe

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06/29/2020 11:35 AM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
That’s really interesting news, all kinds of processes that can turn one kind of cell into another sheds more light and opens up new treatment possibilities.

fivestars
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Triteia

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06/29/2020 11:53 AM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
YAY!!!

My dad died from that horrid disease.

I am SO HAPPY to hear this news.
I hope it helps MANY and this disease is irradiated from the face of the Earth.
Triteia
Anonymous Coward
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06/29/2020 11:57 AM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
They make huge discoveries all the time, most of it is never used though.
SaintPattysPug
Take a Cookie...You'll feel better

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06/29/2020 01:15 PM

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Re: Accidental discovery leads to Parkinson’s disease cure in mice
They make huge discoveries all the time, most of it is never used though.
 Quoting: Anonymous Coward 18002994


Whether or NOT this new discovery paves the way to the cure
for Parkinsons...I am sorry to say...depends on the
"hit" to their finances "Big Pharma" will suffer if the
disease is cured.

It really is all about the money. If the eventual cure
can be marketed at the SAME INCOME or GREATER than what
the Big Medicine gets from current Parkinsons sufferers
then we are home free. If a short-fall...then we won't
see a cure.

Sounds really jaded but that's the way medicine in the
West works now. It is a BUSINESS--and a brutal one where
money is concerned--not a fairy Godmother wanting a happy ending
to a personal tragedy. It wasn't always this way
...not sure how this all happened but my bet would be
corrupt politicians.

Follow the money.

:money:
cheers
S.P.Pug

Last Edited by The Oracle's Cookie on 06/29/2020 01:16 PM
Anonymous Coward (OP)
User ID: 77586330
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06/29/2020 01:17 PM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
That’s really interesting news, all kinds of processes that can turn one kind of cell into another sheds more light and opens up new treatment possibilities.

:fivestars:
 Quoting: Red Hot Chilean Pepe


It really is

boom33
:mindblown:
Anonymous Coward (OP)
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06/29/2020 01:19 PM
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Re: Accidental discovery leads to Parkinson’s disease cure in mice
Now they need to try it on mice with the degeneration caused genetically rather than being chemically induced.

Still, it's like some science fiction right out of a movie or something.





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