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Message Subject WARNING: Renowned Virologist Sucharit Bhakdi Warns Against Hastily Created Gene-Altering Coronavirus Vaccine
Poster Handle Anonymous Coward
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Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes.
 Quoting: Anonymous Coward 79627123


Someone is paying attention. Let's not forget these "awesome shots" get your cells to create a fragment of the "virus", supposedly so that when the whole "virus" got into your body, then your body would attack it.

Wouldn't this mean that your body would then start attacking itself because it is producing a fragment, possibly indefinitely?

With that, wouldn't that mean you have acquired, at minimum, auto-immune deficiency requiring more pharma meds for the rest of your life?

Regardless, anyone wonder what happens long-term when your body is creating a fragment of the "virus"?

wtf
 Quoting: Ricerona 78334071


This is something I've been looking for clarification on. I believe it does use Self-amplifiying mRNA, but I've also heard that it is self limiting. I'd like someone to explain to me what causes an end to the self-amplification.
 Quoting: chrion777


I believe the answer may be this:

The RNA polymerase determines the amount of cycles of self-amplification and eventually it is 'used up'. It does not integrate into the gnome. In that way it's almost like a time-release or a 'timed' set of instructions to produce the protein.

I would like someone that understands this better to confirm and explain in more detail.



[link to www.frontiersin.org (secure)]

"Self-amplifying mRNAs (~9–11 kb) are generated from the DNA template with similar procedures to those previously described for conventional mRNAs and RNA molecules can be produced at a large scale in vitro. After the purified RNA replicon is delivered into host cells, either as viral particles or as synthetically formulated RNA, it is translated extensively and amplified by its encoding RNA-dependent RNA polymerase. Compared with the rapid expression of conventional mRNAs, published results have shown that vaccination with self-amplifying mRNA vaccines results in higher antigen expression levels, although delayed in time, which persist for several days in vivo. Equivalent protection is conferred but at a much lower RNA dose (31). Due to the lack of viral structural proteins, the replicon does not produce infectious viral particles. Additionally, both conventional mRNA and self-amplifying mRNAs cannot potentially integrate into the host genome and will be degraded naturally during the process of antigen expression. These characteristics indicate that mRNA vaccines have the potential to be much safer than other vaccines and are a promising vaccine platform."
 Quoting: chrion777


 
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