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Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

 
Anonymous Coward
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05/22/2021 03:52 PM
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Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19

[link to www.nature.com (secure)]

Here we go...

They are coming in your nearest vaccination center, very soon.
Anonymous Coward (OP)
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05/22/2021 03:53 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Published: 18 May 2021
Anonymous Coward (OP)
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05/22/2021 03:59 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
[link to www.ncbi.nlm.nih.gov (secure)]

Current updates and research on plant-based vaccines for coronavirus disease 2019

Jan, 2021
Anonymous Coward
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05/22/2021 04:02 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
I've been following this for a few months. It's good the trials are going well. But they are still going to add something by Glaxo Kline Smith.
Anonymous Coward (OP)
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05/22/2021 04:56 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
I've been following this for a few months. It's good the trials are going well. But they are still going to add something by Glaxo Kline Smith.
 Quoting: Anonymous Coward 80344936


Will follow up on this and add anything new as it evolves, it will be very interesting, because the future is entirely green vaccines, from genetically modified plants.
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05/22/2021 05:07 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
[link to cordis.europa.eu (secure)]

Plant Nicotiana benthamiana is currently used as a bio-factory for several experimental vaccines against
SARS-COV-2.
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05/22/2021 05:09 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
[link to en.wikipedia.org (secure)]

Nicotiana_benthamiana
Anonymous Coward (OP)
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05/22/2021 05:11 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
[link to en.wikipedia.org (secure)]

Nicotiana_benthamiana
 Quoting: Anonymous Coward 80396595


[link to www.nbenth.com (secure)]

Nicotiana benthamiana

Reference quality, Chromosome level, Genome Assembly v3.3
Anonymous Coward (OP)
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Anonymous Coward (OP)
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05/22/2021 05:14 PM
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[link to cordis.europa.eu (secure)]

Developing Multipurpose Nicotiana Crops for Molecular Farming using New Plant Breeding Techniques

Grant Agreement No 760331
Anonymous Coward (OP)
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05/22/2021 05:21 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
The production of vaccines in transgenic plants was first proposed in 1990 however no product has yet reached commercialization.

There are several risks during the production and delivery stages of this technology, with potential impact on

- the environment and on

-human health.

Risks to the environment include gene transfer and exposure to antigens or selectable marker proteins.

Risks to human health include oral tolerance, allergenicity, inconsistent dosage, worker exposure and unintended exposure to antigens or selectable marker proteins in the food chain.

[link to pubmed.ncbi.nlm.nih.gov (secure)]

August 2005
Anonymous Coward (OP)
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05/22/2021 05:26 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
[link to pubmed.ncbi.nlm.nih.gov (secure)]

Feb, 2020

Edible Vaccines: Promises and Challenges

Vaccines are biological preparations that improve immunity to particular diseases and form an important innovation of 19th century research.

It contains a protein that resembles a disease-causing microorganism and is often made from weak or killed forms of the microbe.

Vaccines are agents that stimulate the body's immune system to recognize the antigen.

Now, a new form of vaccine was introduced which will have the power to mask the risk side of conventional vaccines.

This type of vaccine was produced from plants which are genetically modified. In the production of edible vaccines, the gene-encoding bacterial or viral disease-causing agent can be incorporated in plants without losing its immunogenic property.

The main mechanism of action of edible vaccines is to activate the systemic and mucosal immunity responses against a foreign disease-causing organism.

Edible vaccines can be produced by incorporating transgene in to the selected plant cell.
Anonymous Coward
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05/22/2021 05:31 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Dated 21 September 1996

[link to www.newscientist.com (secure)]
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Plant-based vaccines and antibodies to combat COVID-19: current status and prospects

Dec, 3, 2020

Plant Biopharming.

[link to pubmed.ncbi.nlm.nih.gov (secure)]


Abstract
Globally, researchers are undertaking significant efforts to design and develop effective vaccines, therapeutics, and antiviral drugs to curb the spread of coronavirus disease 2019 (COVID-19). Plants have been used for the production of vaccines, monoclonal antibodies, immunomodulatory proteins, drugs, and pharmaceuticals via molecular farming/transient expression system and are considered as bioreactors or factories for their bulk production. These biological products are stable, safe, effective, easily available, and affordable.

Read more on the link above.
Anonymous Coward (OP)
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05/22/2021 05:35 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
Dated 21 September 1996

[link to www.newscientist.com (secure)]
 Quoting: Anonymous Coward 78063540


banana-vaccines!!!

ana
Anonymous Coward (OP)
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05/22/2021 05:40 PM
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Re: Phase 1 randomized trial of a plant-derived virus-like particle vaccine for COVID-19
We have everything covered as it seems, so we have a good past, a promised future on this field and if you invest now money on this field, you will get rich, 100% guaranteed.

Pity that have no money to invest...LOL!

Oh well, will wait for the oral pill of genetically modified plant, so to get saved from this virus that all talk about, probably it will be produced in flavors as well, so would love to chew it, lick it, and slowly be healthy as new.

Now, it is not a joke, invest and you will become rich, and very quickly also.





GLP