Godlike Productions - Discussion Forum
Users Online Now: 2,365 (Who's On?)Visitors Today: 776,291
Pageviews Today: 1,664,330Threads Today: 869Posts Today: 17,203
11:01 PM


Rate this Thread

Absolute BS Crap Reasonable Nice Amazing
 

Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t

 
Anonymous Coward
User ID: 79427900
10/14/2021 05:34 PM
Report Abusive Post
Report Copyright Violation
Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t
Stanford Report, July 11, 2001

Researchers discover nicotine stimulates growth of new blood vessels

BY KRISTA CONGER

Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals that promote the formation of new blood vessels. The new vessels then deliver oxygen and nutrients to the interior of tumors and plaque deposits.

The Stanford researchers were surprised to find how strongly nicotine stimulates new blood vessel growth, a process known as angiogenesis.

"We expected to see that nicotine impairs angiogenesis because it's known that smoking impairs endothelial function," said Chris Heeschen, the first author of the paper and a postdoctoral fellow in cardiovascular medicine in Cooke's laboratory. "But nicotine is not smoking."

Under some experimental conditions the magnitude of nicotine's effect was comparable to that seen with naturally occurring proteins involved in angiogenesis. In every case, chemicals known to inhibit other molecules associated with angiogenesis also blocked the effect of nicotine -- confirming that nicotine affects blood vessel formation.

The researchers began the study by testing whether nicotine could stimulate the division of cultured endothelial cells. They found that nicotine was as effective as vascular endothelial growth factor, or VEGF -- a naturally occurring, well-defined protein that has long been known to enhance endothelial cell proliferation. Cells cultured in the presence of nicotine or VEGF also assembled themselves into whorls in the tissue culture dish -- perhaps a preliminary step to forming new blood vessels. Chemicals that block nicotine's binding to the receptor also blocked proliferation of the cells.

Read the full article:

[link to news.stanford.edu (secure)]
Anonymous Coward (OP)
User ID: 79427900
10/14/2021 05:38 PM
Report Abusive Post
Report Copyright Violation
Re: Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t
The Subject line should have read:

Researchers discover nicotine stimulates growth of new blood vessels

But not going to double post, oh well.
Anonymous Coward
User ID: 80752635
Netherlands
10/14/2021 05:57 PM
Report Abusive Post
Report Copyright Violation
Re: Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t
fuckyeah5
Anonymous Coward
User ID: 81000919
United States
10/14/2021 10:05 PM
Report Abusive Post
Report Copyright Violation
Re: Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t
Nicotine can reduce vaccine induced gayness.
Anonymous Coward
User ID: 80999801
United States
10/14/2021 10:19 PM
Report Abusive Post
Report Copyright Violation
Re: Researchers speculate that when nicotine binds to the receptor on endothelial cells it stimulates the cells to release a cascade of chemicals t
smoking1

Thread: Why does the FDA really want to ban Menthol cigarettes?





GLP