FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects | |
S-man User ID: 80994243 01/13/2022 04:42 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Uncle Doom, Quoting: S-man 80505408 I was AMAZED - literally amazed when I ran the spike through the PLAAC and PAPA algos for prion-genic sites. ALL the dangerous sites had been scrubbed from the spike. On this front, what I am still concerned about is the Nucleocapsid which - when I looked at Wuhan-1 - still had a huge prion propensity. Do you have any thoughts on the above? Apart from this, the change to endosomal infection from ACE2/TMPRSS2 seems to be KEY to lowering pathogenicity in the lungs, and giving the body time to react properly in the upper-respiratory (tonsils?). If HCQ is an endosomal infection inhibitor (it is, afaik) then what about a re-evaluation of HCQ? e.g.: I think am on to something with the Glasgow Preprint. Quoting: S-man [link to www.gla.ac.uk (secure)] The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17: Omicron spike has switched entry route preference See Figure 6A. The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..). BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers". This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis. [link to journals.plos.org (secure)] Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection Drugs targeting Cathepsin B/L are under development. Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity. [link to www.researchgate.net (secure)] After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution? Stock up on HCQ?? How crazy would it be to find that HCQ really is a solution to this part of the puzzle? I missed the Cathepsin part completely; you are correct! In theory it could be used as a treatment. Quoting: d_senti To recap: Omicron uses 'Route 2' endocytosis, NOT so much ACE2/TMPRSS2. This means it is likely treatable with HCQ, Cathepsin-L inhibitors and such. I also believe that Omicron will do less organ damage, Kidney, Heart, Brain/CNS/PNS, because it prefers 'Route 2' - not ACE2/TMPRSS2 entry. and on top of everything else, that 'Route 2' gives the body a warning period via the tonsils. Last Edited by S-man on 01/13/2022 04:43 AM |
Roughwildfly User ID: 68273222 01/13/2022 05:17 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Another Covid Update Quoting: Anonymous Coward 81056983 Family of four with Omicron 1 Vaccinated - scratchy throat, little tired and sore runny nostril from test. 3 Unvaccinated - Dry throat for a few mornings. 14 days since Positive test, did not disrupt anything in our lives accept paid leave. And defiantly No long Covid symptoms for the time being. Source 55 year old from work came back from 2 weeks of sick leave, Did not take any vitamins, supplements or medicine. Back to life. I hope you dont. But my LC took 3 months to show an issue I apologise for my spelling and grammar, Dyslexia is a biatch. But add on MS and its a whole new world of magic spelling and rambling. We all love green, thanks in advance :) So thats how it is, deal with it or keep walking. We all love green. Thanks in advance :) |
lightning1977 User ID: 44316514 United Kingdom 01/13/2022 05:32 AM Report Abusive Post Report Copyright Violation | |
Doommonkey User ID: 59390060 United States 01/13/2022 05:33 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects 'Omicron appears, after close scrutiny in the field, to be the best, worst case offering* that could have been created and released (in such a short window of time that their team had to hand) in order to act as a firebreak that is easily spread through all forms of close contact*. I applaud the effort, as Omicron is eminently treatable at all stages, and if a public-wide usage of prophylaxis were put in place? We would see an ending to most, if not all, restrictions and deaths.' Quoting: Uncle Doom 81039128 * That the creator designed this without utilizing the ferociously malicious coding originally provided to academia and research, is to be congratulated. ** R0 of similar, if not higher, reach than classical Measels. ^^^^ Mrs Doom's email to one of the people who retain her services. Omicron is engineered. itis a fire break. The best that could be done in such a short space of time whilstremaining hidden from official view. A fire break whilst a better, sterilizing effort can be created and distributed. Writing on the phone so not the best im afraid. Much love Uncle Doom I thought you were saying that this was the sneaky variant that went straight for the CNS and was causing horrible damage? Have you changed your mind on that, or do you have new information? Looks like freedom but it feels like death. It's something in between I guess... it's closing time. Lenonard Cohen |
Doommonkey User ID: 59390060 United States 01/13/2022 06:17 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects |
lightning1977 User ID: 44316514 United Kingdom 01/13/2022 06:19 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects https://twitter.com/_/status/1481585924555386881 https://twitter.com/_/status/1481581547841110025 |
lightning1977 User ID: 44316514 United Kingdom 01/13/2022 06:51 AM Report Abusive Post Report Copyright Violation | |
Roughwildfly User ID: 68273222 01/13/2022 06:55 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Maybe useful for sman [link to www.ons.gov.uk (secure)] I apologise for my spelling and grammar, Dyslexia is a biatch. But add on MS and its a whole new world of magic spelling and rambling. We all love green, thanks in advance :) So thats how it is, deal with it or keep walking. We all love green. Thanks in advance :) |
whitepiedtv User ID: 81772526 Singapore 01/13/2022 07:06 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Possible Omicron with Stroke https://twitter.com/_/status/1481518080949776385 https://twitter.com/_/status/1481471971439300608 https://twitter.com/_/status/1481152773853007872 https://twitter.com/_/status/1481030777777369088 https://twitter.com/_/status/1481028442221166594 https://twitter.com/_/status/1481025178695974916 https://twitter.com/_/status/1481015600088555525 |
S-man User ID: 81645476 01/13/2022 07:39 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Thanks, but Prof. Fenton has shown that the ONS have systematically mis-classified deaths by vax-status.. so our recourse now is to look at all-cause mortality alone. Norman found some astonishing details - like: "we have shown a range of fundamental inconsistencies and flaws in the data. Specifically.." • In 2021 each age group has non-Covid mortality peaks for the unvaccinated at a different time, namely the time that vaccination rollout programmes for those cohorts reach a peak. • The peaks in the Covid mortality data for the unvaccinated are inconsistent with the actual Covid wave. [link to youtu.be (secure)] 5m20s: "UNVAXXED SEEM TO BE DYING AFTER NOT GETTING 1ST DOSE & 1ST DOSED PEOPLE DYING AFTER NOT GETTING 2ND DOSE." -simple explanation is simple mis-categorisation of "freshly-vaccinated" as "unvaccinated". 6m20s: "UNVAXXED DYING OF COVID WHEN VAX ROLLS OUT" hmm! Report: [link to www.researchgate.net (secure)] Concise presentation by Prof. Fenton: [link to rumble.com (secure)] Last Edited by S-man on 01/13/2022 07:40 AM |
Anonymous Coward User ID: 78714632 United States 01/13/2022 07:46 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects More scary looking videos from China Quoting: lightning1977 https://twitter.com/_/status/1481585924555386881 https://twitter.com/_/status/1481581547841110025 Looks like a scene from I Am Legend |
S-man User ID: 81458678 01/13/2022 08:05 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects OT: What does one do about red karma obtained for simply enetering into a civil discussion with Cannabis Kills People? Can it be got rid of? Requested from a mod? I only use my karma to pin threads here when they are of real importance (like the USMC docs, or Paramedic's "infection rates among vaxxed" thread).. Last Edited by S-man on 01/13/2022 08:06 AM |
Anonymous Coward User ID: 79324350 United States 01/13/2022 08:23 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects OT: Quoting: S-man What does one do about red karma obtained for simply enetering into a civil discussion with Cannabis Kills People? Can it be got rid of? Requested from a mod? I only use my karma to pin threads here when they are of real importance (like the USMC docs, or Paramedic's "infection rates among vaxxed" thread).. What bad karma? |
S-man User ID: 81458678 01/13/2022 08:27 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Thread: [link to godlikeproductions.com] UPDATE: He Is RESIGNING! -England's Deputy Chief Medical Officer AUTHORS paper on COVID Anti-Viral.. ....crickets! Where are the Journos?! ..the study, published in Viruses. Quoting: S-man The chemical is Thapsigargin. [link to pubmed.ncbi.nlm.nih.gov (secure)] but here's the kicker: authors: Sarah Al-Beltagi 1 , Cristian Alexandru Preda 1 , Leah V Goulding 2 , Joe James 3 , Juan Pu 4 , Paul Skinner 3 , Zhimin Jiang 4 , Belinda Lei Wang 1 , Jiayun Yang 1 , Ashley C Banyard 3 , Kenneth H Mellits 5 , Pavel Gershkovich 6 , Christopher J Hayes 7 , Jonathan Nguyen-Van-Tam 8 , Ian H Brown 3 , Jinhua Liu 4 , Kin-Chow Chang 1 That name (Van-Tam) should be familiar to anyone in the UK. He's one of the UK Government's "TV faces" of the pandemic! He's the England's Deputy Chief Medical Officer. Can ANY journalist worth their salt ask Van-Tam live on air what has happened to his broad-spectrum antiviral in the fight against COVID? The paper was published in February! Are the UK Gov able to conduct and publicise research properly whilst contracting with Pfizer, AZ, Moderna etc.? Looks like Van-Tam can't tolerate the Government's B.S. line of "vax-or-nothing" any more! Last Edited by S-man on 01/13/2022 09:37 AM |
S-man User ID: 81458678 01/13/2022 08:31 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects OT: Quoting: S-man What does one do about red karma obtained for simply enetering into a civil discussion with Cannabis Kills People? Can it be got rid of? Requested from a mod? I only use my karma to pin threads here when they are of real importance (like the USMC docs, or Paramedic's "infection rates among vaxxed" thread).. What bad karma? Whoa... if that was you, you're a (*). Beers are on me, If I can ever make it to New England. |
Genetics User ID: 81848395 Australia 01/13/2022 09:15 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Genetics Have Always Mattered and Are Everything With Covid [link to www.yahoo.com (secure)] Thu, January 13, 2022, 7:03 AM·1 min read WARSAW (Reuters) - Polish scientists have found a gene that they say more than doubles the risk of becoming severely ill with COVID-19, a discovery they hope could help doctors identify people who are most at risk from the disease. Other studies have also shown the importance of genetic factors in how seriously COVID-19 develops. In November, British scientists said they had identified a version of a gene that may be associated with double the risk of lung failure from COVID-19. Somebody was wrong again . |
Anonymous Coward User ID: 81775844 01/13/2022 09:34 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Possible Omicron with Stroke Quoting: whitepiedtv https://twitter.com/_/status/1481518080949776385 https://twitter.com/_/status/1481471971439300608 https://twitter.com/_/status/1481152773853007872 https://twitter.com/_/status/1481030777777369088 https://twitter.com/_/status/1481028442221166594 https://twitter.com/_/status/1481025178695974916 https://twitter.com/_/status/1481015600088555525 I don’t see this being less organ damage. Just different and not immediately for all. |
Roughwildfly User ID: 68273222 01/13/2022 09:42 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects So if antibodies are high, but they need the 3rd dose, but antibodies play no part in infection control, how are the 3rd jabs protecting. Does the body lose its b and t cells memory? Anyone shed light on the mechanisms https://twitter.com/_/status/1481562122161201152 I apologise for my spelling and grammar, Dyslexia is a biatch. But add on MS and its a whole new world of magic spelling and rambling. We all love green, thanks in advance :) So thats how it is, deal with it or keep walking. We all love green. Thanks in advance :) |
Roughwildfly User ID: 68273222 01/13/2022 09:44 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Is this them admitting that the vac does indeed kill some poor souls, but does stop a rush on the hospital, so i guess a win for the vac. https://twitter.com/_/status/1481634049433255939 I apologise for my spelling and grammar, Dyslexia is a biatch. But add on MS and its a whole new world of magic spelling and rambling. We all love green, thanks in advance :) So thats how it is, deal with it or keep walking. We all love green. Thanks in advance :) |
No one at all User ID: 80892386 United States 01/13/2022 09:45 AM Report Abusive Post Report Copyright Violation | |
Anonymous Coward User ID: 81775844 01/13/2022 09:52 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Oh my fucking hell. The WHO still thinks this has an ending and refuses to call it endemic. Quoting: CleverCreator It’s here. It’s. Fucked. How can this idiot keep a straight face? He knows what we know. [link to twitter.com (secure)] https://twitter.com/_/status/1481422013650677762 |
S-man User ID: 80965890 01/13/2022 10:17 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Is this them admitting that the vac does indeed kill some poor souls, but does stop a rush on the hospital, so i guess a win for the vac. Quoting: Roughwildfly https://twitter.com/_/status/1481634049433255939 Fascinating stuff..reading.. My take: he's shown that the ONS' explanation is BS, and they owe us answers about the spikes in unvaxxed non-covid deaths as the vax rolls out.. Here is a threadreaderapp of Martin Neil's analysis (He works with Norman Fenton afaik). [link to threadreaderapp.com (secure)] -Archive it, cos we konw they disappear when the twatter account gets nuked! |
LJS Forum Administrator 01/13/2022 10:21 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Genetics Have Always Mattered and Are Everything With Covid [link to www.yahoo.com (secure)] Thu, January 13, 2022, 7:03 AM·1 min read WARSAW (Reuters) - Polish scientists have found a gene that they say more than doubles the risk of becoming severely ill with COVID-19, a discovery they hope could help doctors identify people who are most at risk from the disease. Other studies have also shown the importance of genetic factors in how seriously COVID-19 develops. In November, British scientists said they had identified a version of a gene that may be associated with double the risk of lung failure from COVID-19. Somebody was wrong again . So, it was engineered to target certain genetics. Color me shocked. Fate whispers to the warrior "You cannot withstand the storm" the warrior whispers back "I am the storm" INTJ-A |
S-man User ID: 80965890 01/13/2022 10:25 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects So if antibodies are high, but they need the 3rd dose, but antibodies play no part in infection control, how are the 3rd jabs protecting. Quoting: Roughwildfly Does the body lose its b and t cells memory? Anyone shed light on the mechanisms https://twitter.com/_/status/1481562122161201152 The AB's produced in people naturally infected react with *all* the proteins in the virus to some extent, but the vaccines produce only anti-Spike ABs. Those are not neutralising any more, as they are out-of date for the cirulating virus (Omicron). -There are Antibodies, and there are Antibodies. Also, the vaccines themselves diminish the Adaptive Immune system by impairing DNA damage repair (double-strand breaks, see below..) I saw Dr Been describe this DNA-mending impairment as causing the b and t-cells to have less variability; less able to cope with variants. [link to www.youtube.com (secure)] (intro 3 mins onwards, meat starts at 6m50s, t,b-cells/proliferation at 13m, b,t-cell variability 14m, DNA-repair effect on t,b-cells 19m) [link to www.mdpi.com (secure)] SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro "we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site. Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines" Last Edited by S-man on 01/13/2022 10:57 AM |
Lago User ID: 81536351 United States 01/13/2022 10:27 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Coronavirus India Live Updates: India Records 2,47,417 New Covid Cases, 27% Higher Than Yesterday (Jan 12 --442,137)... [link to www.ndtv.com (secure)] Remember this? Uttar Pradesh government says early use of Ivermectin helped to keep positivity, deaths low .. [link to www.msn.com (secure)] In Uttar Pradesh, active cases climb to 57,355; positivity rate 5.70%. ... [link to indianexpress.com (secure)] Last Edited by Lago on 01/13/2022 02:12 PM Lago |
S-man User ID: 80965890 01/13/2022 10:34 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Coronavirus India Live Updates: India Records 2,47,417 New Covid Cases, 27% Higher Than Yesterday ... [link to www.ndtv.com (secure)] Quoting: Lago Remember this? Uttar Pradesh government says early use of Ivermectin helped to keep positivity, deaths low .. [link to www.msn.com (secure)] In Uttar Pradesh, active cases climb to 57,355; positivity rate 5.70%. ... [link to indianexpress.com (secure)] They arent using it atm? They know how to control it, but they might decide not to bother, if it is not that serious. Last Edited by S-man on 01/13/2022 10:35 AM |
Lago User ID: 81536351 United States 01/13/2022 10:43 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects SC, i woulda took a bleach bath and misted my nose and mouth with bleach steam. wouldn't been the 1st time either. when i had to go to the ER, i damn near jumped in with my clothes. plus went to horsey for few days. Quoting: JAZZz50 When you say a "bleach bath" and "bleach steam" what % of bleach are you putting in the water and what type of bleach are you using Jazz? Lago |
Lago User ID: 81536351 United States 01/13/2022 10:48 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects SC, i woulda took a bleach bath and misted my nose and mouth with bleach steam. wouldn't been the 1st time either. when i had to go to the ER, i damn near jumped in with my clothes. plus went to horsey for few days. Quoting: JAZZz50 I did a Neti Pot as SOON as I got home! Forgot to add that in Nasal Irrigation to Reduce COVID-19 Morbidity.. [link to clinicaltrials.gov (secure)] Interesting... Lago |
Lago User ID: 81536351 United States 01/13/2022 10:51 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Coronavirus India Live Updates: India Records 2,47,417 New Covid Cases, 27% Higher Than Yesterday ... [link to www.ndtv.com (secure)] Quoting: Lago Remember this? Uttar Pradesh government says early use of Ivermectin helped to keep positivity, deaths low .. [link to www.msn.com (secure)] In Uttar Pradesh, active cases climb to 57,355; positivity rate 5.70%. ... [link to indianexpress.com (secure)] They arent using it atm? They know how to control it, but they might decide not to bother, if it is not that serious. That is a pretty thin assumption given that Covid is probably all around them (probably 10 times official number), and that older members of their family are probably really suffering. Also, officially, the Omicron variant is only justing starting..."The country witnessed 620 new Omicron cases". ????.... [link to www.financialexpress.com (secure)] Last Edited by Lago on 01/13/2022 10:59 AM Lago |
Anonymous Coward User ID: 81775844 01/13/2022 10:58 AM Report Abusive Post Report Copyright Violation | Re: FOR CORONACOASTER: COVID-19 News, Info, Discussion /// Tracking the Spread of the Virus and its Effects Genetics Have Always Mattered and Are Everything With Covid [link to www.yahoo.com (secure)] Thu, January 13, 2022, 7:03 AM·1 min read WARSAW (Reuters) - Polish scientists have found a gene that they say more than doubles the risk of becoming severely ill with COVID-19, a discovery they hope could help doctors identify people who are most at risk from the disease. Other studies have also shown the importance of genetic factors in how seriously COVID-19 develops. In November, British scientists said they had identified a version of a gene that may be associated with double the risk of lung failure from COVID-19. Somebody was wrong again . So, it was engineered to target certain genetics. Color me shocked. Yeah, but what troll fan is trying to say is its family is untouchable. And that is wrong. This was NOT a completed project. My theory still stands - up front it looks like it works, but over time and multiple infections this genetics thing won’t hold water because it will cause damage over and over again. He just hates where the information came from. And it is not telling the truth about its history. Because it needs to be anti-Semitic. |