So if antibodies are high, but they need the 3rd dose, but antibodies play no part in infection control, how are the 3rd jabs protecting.
Does the body lose its b and t cells memory?
Anyone shed light on the mechanisms
Quoting: Roughwildfly The AB's produced in people naturally infected react with *all* the proteins in the virus to some extent, but the vaccines produce only anti-Spike ABs. Those are not neutralising any more, as they are out-of date for the cirulating virus (Omicron).
-There are Antibodies, and there are
Antibodies.
Also, the vaccines themselves diminish the Adaptive Immune system by impairing DNA damage repair (double-strand breaks, see below..)
I saw Dr Been describe this DNA-mending impairment as causing the b and t-cells to have less variability; less able to cope with variants. [
link to www.youtube.com (secure)] (intro 3 mins onwards, meat starts at 6m50s, t,b-cells/proliferation at 13m, b,t-cell variability 14m, DNA-repair effect on t,b-cells 19m)
[
link to www.mdpi.com (secure)]
SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro "we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity. Mechanistically, we found that the
spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site. Our findings reveal a potential molecular mechanism by which the
spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines"