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HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ

 
S-man
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HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?

Last Edited by S-man on 10/31/2022 06:12 AM
S-man  (OP)

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
More corroboration. ACEII/TMPRSS2 route blocked (confirming endocytosis route far more important).

From Univ. of Cambridge:
[link to www.zerohedge.com (secure)]
"Many cells in the lung carry a protein called TMPRSS2 on their surface that can inadvertently help passing viruses gain entry to the cell. But Dr. Gupta’s team found that this protein doesn’t grab on to Omicron very well. As a result, Omicron does a worse job of infecting cells in this manner than Delta does. A team at the University of Glasgow independently came to the same conclusion."


Again:
What I am saying is: there is now just cause to re-evaluate HCQ in the light of the knowledge from the Glasgow preprint.
 Quoting: S-man
S-man  (OP)

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Our forefathers definitely knew something about upper respiritory tract infections.
[link to ibb.co (secure)]
You see all those manufacturers? Hill's, Grove's, Rawleigh's.. they were successful for a reason.

As the Glasgow preprint (and now Cambridge Uni, too) pointed out, Omicron has largely lost the ability to use the Furin Cleavage Site PRRA with ACE2 and TMPRSS2 --which was the novel part of this virus!-- No other Human Betacoronavirus had the Furin Cleavage Site..

Omicron prefers the endosomal route.. thus it has a vulnerabilty to endosomal blockers E64d - like Quinine, Bromoquine, Chloroquine, ...

HCQ must be re-evaluated!
 Quoting: S-man 81494257
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Our forefathers definitely knew something about upper respiritory tract infections.
[link to ibb.co (secure)]
You see all those manufacturers? Hill's, Grove's, Rawleigh's.. they were successful for a reason.

As the Glasgow preprint (and now Cambridge Uni, too) pointed out, Omicron has largely lost the ability to use the Furin Cleavage Site PRRA with ACE2 and TMPRSS2 --which was the novel part of this virus!-- No other Human Betacoronavirus had the Furin Cleavage Site..

Omicron prefers the endosomal route.. thus it has a vulnerabilty to endosomal blockers E64d - like Quinine, Bromoquine, Chloroquine, ...

HCQ must be re-evaluated!
 Quoting: S-man 81494257

 Quoting: S-man


5star-post

Outstanding thread again as usual

Cinchona bark and cannabis incense was used during religious ceremonies for centuries

Buddhist monks claim Jesus came to India and became a Buddhist monk and that the Catholic Church covered it all up just like Sir Isaac Newton's work is a code in and of itself

Organic Catholic communion bread can be substituted with tofu which contains Lactone

The same chemical in Ivermectin

banned02
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01/02/2022 09:09 AM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Our forefathers definitely knew something about upper respiritory tract infections.
[link to ibb.co (secure)]
You see all those manufacturers? Hill's, Grove's, Rawleigh's.. they were successful for a reason.

As the Glasgow preprint (and now Cambridge Uni, too) pointed out, Omicron has largely lost the ability to use the Furin Cleavage Site PRRA with ACE2 and TMPRSS2 --which was the novel part of this virus!-- No other Human Betacoronavirus had the Furin Cleavage Site..

Omicron prefers the endosomal route.. thus it has a vulnerabilty to endosomal blockers E64d - like Quinine, Bromoquine, Chloroquine, ...

HCQ must be re-evaluated!
 Quoting: S-man 81494257

 Quoting: S-man


5star-post

Outstanding thread again as usual

Cinchona bark and cannabis incense were used during religious ceremonies for centuries

Buddhist monks claim Jesus came to India and became a Buddhist monk and that the Catholic Church covered it all up just like Sir Isaac Newton's work is a code in and of itself

Organic Catholic communion bread can be substituted with tofu which contains Lactone

The same chemical in Ivermectin

banned02
 Quoting: Anonymous Coward 81734451


vendetta
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01/02/2022 09:34 AM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Our forefathers definitely knew something about upper respiritory tract infections.
[link to ibb.co (secure)]
You see all those manufacturers? Hill's, Grove's, Rawleigh's.. they were successful for a reason.

As the Glasgow preprint (and now Cambridge Uni, too) pointed out, Omicron has largely lost the ability to use the Furin Cleavage Site PRRA with ACE2 and TMPRSS2 --which was the novel part of this virus!-- No other Human Betacoronavirus had the Furin Cleavage Site..

Omicron prefers the endosomal route.. thus it has a vulnerabilty to endosomal blockers E64d - like Quinine, Bromoquine, Chloroquine, ...

HCQ must be re-evaluated!
 Quoting: S-man 81494257

 Quoting: S-man


youknow

Our forefathers definitely knew something about upper respiritory tract infections.
[link to ibb.co (secure)]
You see all those manufacturers? Hill's, Grove's, Rawleigh's.. they were successful for a reason.

As the Glasgow preprint (and now Cambridge Uni, too) pointed out, Omicron has largely lost the ability to use the Furin Cleavage Site PRRA with ACE2 and TMPRSS2 --which was the novel part of this virus!-- No other Human Betacoronavirus had the Furin Cleavage Site..

Omicron prefers the endosomal route.. thus it has a vulnerabilty to endosomal blockers E64d - like Quinine, Bromoquine, Chloroquine, ...

HCQ must be re-evaluated!
 Quoting: S-man 81494257

 Quoting: S-man


5star-post

Outstanding thread again as usual

Cinchona bark and cannabis incense were used during religious ceremonies for centuries

Buddhist monks claim Jesus came to India and became a Buddhist monk and that the Catholic Church covered it all up just like Sir Isaac Newton's work is a code in and of itself

Organic Catholic communion bread can be substituted with tofu which contains Lactone

The same chemical in Ivermectin

banned02
 Quoting: Anonymous Coward 81734451


vendetta
 Quoting: Updated 81734451
Anonymous Coward
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01/02/2022 09:48 AM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Guess the Qtard members want to bump this off the front page so they can steal it to farm karma

trump-wng1
Hoseman

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
China Balls. Melia azedarach.

[link to www.ncbi.nlm.nih.gov (secure)]

Inhibiting the endocytic machinery

1-cinnamoyl-3,11-dihydroxy meliacarpin Terpenoid Melia azedarach increased endolysosomal pH (EC of 7.5 μM)
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Shut the fuck up dum dum
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?
 Quoting: S-man


Any Zinc ionophore does the same.

Quercetin is easily available as a "poor man's HCQ". Lots of Zinc.

N acetyl cysteine is underappreciated.

Also remember, death in someone with a Vitamin D level greater than 50 is unreported.

As in - doesn't happen. Vit D may be MORE protective than a vaccine.

Chew on that.

10-15k units a day with an MVI for Vit K etc.
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Shut the fuck up dum dum
 Quoting: Anonymous Coward 81082803


shill
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01/02/2022 11:17 AM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?
 Quoting: S-man


I guess its no wonder that the two countries that "baffle" the world due to relatively non existent case numbers , also happen to be the two cuntries that treated the population with HCQ
S-man  (OP)

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
China Balls. Melia azedarach.

[link to www.ncbi.nlm.nih.gov (secure)]

Inhibiting the endocytic machinery

1-cinnamoyl-3,11-dihydroxy meliacarpin Terpenoid Melia azedarach increased endolysosomal pH (EC of 7.5 μM)
 Quoting: Hoseman


~Thanks.
Will look into this.


PS- thanks also to mod for the pin! Nice to know someone caught this, because I don't use any other social media. Perhaps someone somewhere who knows more than I will also read it.
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
hcq works. my girl friend came down with rona last month. popped positive on a home test. 59 year old non-vaxed. healthy no pre-comorbidy.

got her some ivermectin paste and that helped but her recovery process stalled out. then after that my buddy gave us some HCQ he brought back from India in november. day 3 on HCQ she started getting better

i got sick too but not as bad. a bit younger and athletic. lost my smell and taste though.
NOLAangel

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
5stars
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
hcq works. my girl friend came down with rona last month. popped positive on a home test. 59 year old non-vaxed. healthy no pre-comorbidy.

got her some ivermectin paste and that helped but her recovery process stalled out. then after that my buddy gave us some HCQ he brought back from India in november. day 3 on HCQ she started getting better

i got sick too but not as bad. a bit younger and athletic. lost my smell and taste though.
 Quoting: Anonymous Coward 75821963

Bummer...it gradually comes back, but not fun at the start...I had sore feet fo 2 days and lost my taste...fine otherwise...
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Fear sheep porn.
Crypto-Tard

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Baking soda.

In every pantry.

Very cheap.

Works against COVID and cancer.
When you are afraid of losing your life, you have already lost your life.

Don't be afraid.
Pres. Elect Festus Hoggbottom

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
But....but, the retracted, fraudulent study published briefly in the Lancet said it does more harm than good.
I did it. I did it on purpose. And I'll do it again.
Cap’n Obvious

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
hcq works. my girl friend came down with rona last month. popped positive on a home test. 59 year old non-vaxed. healthy no pre-comorbidy.

got her some ivermectin paste and that helped but her recovery process stalled out. then after that my buddy gave us some HCQ he brought back from India in november. day 3 on HCQ she started getting better

i got sick too but not as bad. a bit younger and athletic. lost my smell and taste though.
 Quoting: Anonymous Coward 75821963


Well there is all the proof we need…. A double blind study for sure.

Now what do I do with my massive stash of invermectin? Guess I need to buy some horses now.
You can stand me up at the gates of hell…. I won’t back down.
—————
If it doesn’t seem logical it is likely bullshit.

if it might be possible it is usually bullshit.

If it makes sense it is probably bullshit.
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Guess I will now be having 2 or 3 gin and tonics, instead of just one!
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
Dont tell people leg cramp pills have it, or they will ban the drug.
Halfbreedgal
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I tried to share a YouTube channel that shows you how to make a homemade batch..I think it's called Riverside homestead ... Facebook gave me a message saying it's false information and put a fuzzy thing over my post lol. My own channel is Nellie's farm. I have alternative medicine info on my channel too
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?
 Quoting: S-man

Both myself and coworker got it last week
He took hcq and i took ivermectin
We both also took zpak
Both over it in one day
Anonymous Coward
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
hcq works. my girl friend came down with rona last month. popped positive on a home test. 59 year old non-vaxed. healthy no pre-comorbidy.

got her some ivermectin paste and that helped but her recovery process stalled out. then after that my buddy gave us some HCQ he brought back from India in november. day 3 on HCQ she started getting better

i got sick too but not as bad. a bit younger and athletic. lost my smell and taste though.
 Quoting: Anonymous Coward 75821963


Well there is all the proof we need…. A double blind study for sure.

Now what do I do with my massive stash of invermectin? Guess I need to buy some horses now.
 Quoting: Cap’n Obvious


HCQ + zinc taken early was enough with the Covid in early 2020. For Delta, that was often not enough but ivermectin fixed it. I guess the big news here is that HCQ is enough again for Omicron.

Quercetin is one of several things that do the same thing as HCQ.
Hoseman

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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
But....but, the retracted, fraudulent study published briefly in the Lancet said it does more harm than good.
 Quoting: Pres. Elect Festus Hoggbottom


The Lancet did more harm than good.
Concorde Warrior F-BVFA

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bump
I came. I saw. I Concorde.

For once you have tasted Concorde you will walk the earth with your eyes turned skywards, for there you have been and there you will long to return.

"I would say today we can integrate all religions and races EXCEPT ISLAM."
Singapore's founding father Lee Kuan Y ew
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
But....but, the retracted, fraudulent study published briefly in the Lancet said it does more harm than good.
 Quoting: Pres. Elect Festus Hoggbottom


The Lancet did more harm than good.
 Quoting: Hoseman


Yes, Listento Lance Editor Horton justify his CCP-sycophantic position here:

[link to www.youtube.com (secure)]
Anonymous Coward
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01/02/2022 04:13 PM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
But....but, the retracted, fraudulent study published briefly in the Lancet said it does more harm than good.
 Quoting: Pres. Elect Festus Hoggbottom


The Lancet did more harm than good.
 Quoting: Hoseman


Yes, Listen to Lance Editor Horton justify his CCP-sycophantic position here:

[link to www.youtube.com (secure)]

 Quoting: Anonymous Coward 80310741


18m 55s
Alina Chan actually said the Lancet had evidence of Human-to-Human transmission and didn't publish..also kept suppressed the lab-leak theory.

52m
Then you can listen to Alina Chan hand Horton (Lancet) his own ass when she suggests all the ways The Lancet could have done better!
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?
 Quoting: S-man


That wouldn't be the crazy part at all IMO. The crazy part would be why were so many denigrating it as a possibility when we were still very early in the pandemic and knew very little about this coronavirus?
Anonymous Coward
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01/02/2022 04:52 PM
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Re: HCQ must be re-evaluated! IMPORTANT INFO! Works BEST vs. Omicron! FLCCC re-included HCQ
I think am on to something with the Glasgow Preprint.
[link to www.gla.ac.uk (secure)]

The lack of cell fusion as an entry mechanism by Omicron is documented in the preprint..Page 17:
Omicron spike has switched entry route preference
See Figure 6A.

The other known mechanism of entry (endocytosis) is shown to be used much better by Omicron. (aside: This explains the lower involvement of the lungs in Omicron infections..).

BUT most importantly, the endocytosis route has blockers that can be considered for use.. "Cathepsin blockers".

This paper is older; from when Sars-COV-2 was using the TMPRSS2+Furin Cleavage Site, as well as endocytosis.
[link to journals.plos.org (secure)]
Targeting TMPRSS2 and Cathepsin B/L together may be synergistic against SARS-CoV-2 infection
Drugs targeting Cathepsin B/L are under development.
Hydroxychloroquine is thought to act against SARS-CoV-2 via several mechanisms, including blocking the endocytic pathway.; it suppresses clathrin-mediated virus uptake and also prevents endosomal acidification, the latter required for Cathepsin B/L activity.

[link to www.researchgate.net (secure)]
After one year of COVID-19 Pandemic and Hundreds of Suggested Drugs, Will Cathepsin L Inhibitors be the Solution?


Stock up on HCQ??
How crazy would it be to find that HCQ really is a solution to this part of the puzzle?
 Quoting: S-man


Any Zinc ionophore does the same.

Quercetin is easily available as a "poor man's HCQ". Lots of Zinc.

N acetyl cysteine is underappreciated.

Also remember, death in someone with a Vitamin D level greater than 50 is unreported.

As in - doesn't happen. Vit D may be MORE protective than a vaccine.

Chew on that.

10-15k units a day with an MVI for Vit K etc.
 Quoting: Anonymous Coward 78914005



I am not so retarded that I would even consider chewing on that

You compare apples to poison? What the hell?

Of course vitamin D is better than a suicide shot.





GLP