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COVID Clotting mechanism discovered by Swedish Scientists

 
Doctor Congo

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05/20/2022 07:18 AM

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COVID Clotting mechanism discovered by Swedish Scientists
In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University (LiU), Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The discovery of a possible connection between harmful amyloid production and symptoms of COVID-19 has been published in the Journal of American Chemical Society.
[link to medicalxpress.com (secure)]
-------------------
My synopsis:

-First of all, the American Chemical Society is a huge MAINSTREAM professional organization. The JACS is a peer reviewed journal. These are not conspiracists, they are normal scientists
-Linköping University is one of the biggest universities in Sweden with an emphasis on PhDs.

-When a protein folds into a shape that isn't normal it is called an amyloid. As a result it doesn't act in a normal fashion.
-COVID spike proteins will react to the body's immune system and fold into amyloids
-In another unnatural action the spike protein amyloids join into long chains
-There are 30 other proteins in our body (non COVID related) that can fold this way, and they all lead to unique diseases
--One of these diseases is Alzheimer's, but there are other scary diseases too
-Using computer simulation, the researchers discovered that the coronavirus' spike protein contained seven different sequences which potentially could produce amyloid.
-Three of the seven sequences met the researchers' criteria for being counted as amyloid-producing sequences when experimentally tested. (magic, just like they were designed to do?)
-They produced, among other things, so-called fibrils, which look like long threads when examined under an electron microscope.
-They were able to produce the fibrils in the laboratory environment, but would this happen spontaneously in the body?
-In Alzheimer's the immune system slices and dices large proteins into smaller segments, and then some of the pieces turn into amyloids.
-The researchers were able to show that white blood cells do the same thing to the spike protein.
-A white blood cell type called neutrophils are produced very early after COVID infection, and this is the one that creates the amyloids.
-""We have never seen such perfect, but scary, fibrils as these ones from the amyloid-producing SARS-CoV-2 spike protein and pieces thereof. The fibrils starting from the full-sized spike protein branched out like limbs on a body. Amyloids don't usually branch out like that. We believe that it is due to the characteristics of the spike protein," says Per Hammarström, professor at the Department of Physics, Chemistry and Biology (IFM) at Linköping University." (amazing coincidence)
-Previous research, including a study by South African researchers, has indicated that the spike protein may be involved in the production of small blood clots.
-The blood contains the fibrin protein, which helps the blood to coagulate when a vessel is damaged, so that the hole seals again and stops bleeding. When the injury has begun to heal, the coagulate is supposed to be broken up by plasmin, which is also found in blood.
-The researchers at LiU mixed amyloid-producing protein pieces from the spike protein together with these bodily substances in test tubes, and saw that the fibrin coagulate which was then produced could not be broken down in the usual way by plasmin.
-Disturbed blood coagulation is also seen in many amyloid-related illnesses.
-"We can see that the spike protein, when affected by our own immune system, can produce amyloid structures, and that this can potentially affect our blood coagulation."
-These researchers restrict themselves to talking about micro blood clots, but anyone can see how this could result in huge clots and myocarditis, etc.

(Disclaimer: I was a trauma surgeon, not a research biologist so I am not an expert in this field. And I have been retired for more than 25 years...)
Accidental Stoner

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05/20/2022 07:24 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
Anonymous Coward
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05/20/2022 07:29 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Thread: The VAXX CLOT COMPILATION THREAD!!!
Doctor Congo  (OP)

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05/20/2022 07:29 AM

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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


It is from the spike protein in the disease. The journal paper didn't mention vax status. But when the vax's purpose is to produce more spike proteins then I would assume they are at a much greater risk.

Imagine the evil behind a potential engineered disease and a money making vax that quadruples the possibility of death and disability...

And these researches needed to get this report passed the review panel. Any mention of vax status probably would be risky.

Last Edited by Doctor Congo on 05/20/2022 07:45 AM
Anonymous Coward
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05/20/2022 08:12 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
bump
Doctor Congo  (OP)

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05/20/2022 08:28 AM

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Re: COVID Clotting mechanism discovered by Swedish Scientists
COVID spikes aren't the only proteins that can form amyloids.

Many if not all of them cause diseases. These diseases are forms of amyloidosis. Alzheimer's may be the only one affecting the brain. To learn more: [link to www.webmd.com (secure)]

One of these diseases is called Dialysis-related amyloidosis (DRA), which is linked to being hooked up to a dialysis machine.

Perhaps this new disease could be called COVID-relate amyloidosis (CRA)
Anonymous Coward
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05/20/2022 08:29 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


It is from the spike protein in the disease. The journal paper didn't mention vax status. But when the vax's purpose is to produce more spike proteins then I would assume they are at a much greater risk.

Imagine the evil behind a potential engineered disease and a money making vax that quadruples the possibility of death and disability...

And these researches needed to get this report passed the review panel. Any mention of vax status probably would be risky.
 Quoting: Doctor Congo


Thank you for bringing this article to our attention. Lots of stuff new to me.
Anonymous Coward
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05/20/2022 08:35 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


It is from the spike protein in the disease. The journal paper didn't mention vax status. But when the vax's purpose is to produce more spike proteins then I would assume they are at a much greater risk.

Imagine the evil behind a potential engineered disease and a money making vax that quadruples the possibility of death and disability...

And these researches needed to get this report passed the review panel. Any mention of vax status probably would be risky.
 Quoting: Doctor Congo




so are you saying that the government injected the most dangerous part of the virus into millions of people?
Anonymous Coward
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05/20/2022 08:45 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
COVID spikes aren't the only proteins that can form amyloids.

Many if not all of them cause diseases. These diseases are forms of amyloidosis. Alzheimer's may be the only one affecting the brain. To learn more: [link to www.webmd.com (secure)]

One of these diseases is called Dialysis-related amyloidosis (DRA), which is linked to being hooked up to a dialysis machine.

Perhaps this new disease could be called COVID-relate amyloidosis (CRA)
 Quoting: Doctor Congo


Maybe COVID-spike-protein-related-amyloidosis would be better, so that people realize the vaccine can also produce the Covid amyloids.

Early Covid prophylactics are the best treatment for Covid.
Anonymous Coward
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05/20/2022 08:47 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
yes. i think the only dangerous part of the virus in fact. sounds exactly like prions/ mad cow disease.

all of this was predicted specifically by the original doctors to speak out. They knew this on day one.
Anonymous Coward
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05/20/2022 08:48 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
Anonymous Coward
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05/20/2022 09:03 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
 Quoting: Anonymous Coward 72474072


LMGTFY

"Description. Protein S deficiency is a disorder of blood clotting. People with this condition have an increased risk of developing abnormal blood clots."
Anonymous Coward
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05/20/2022 09:06 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
 Quoting: Anonymous Coward 72474072


I know people who have this disorder. Diagnosed long before Covid. In some cases it causes life threatening clots. Once diagnosed, usually on thinners for life.
Anonymous Coward
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05/20/2022 09:07 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


Most likely jabbed.

The article focuses on what they call "long term COVID", which is complete bullshit.

What they call "COVID" is a bio-weapon.

That bio-weapon can cause all kinds of health problems, some of which can persist, but the actual bio-weapon itself is long gone. What they call "long COVID" is actually symptoms from the damage caused by the bio-weapon, not the bio-weapon itself.

Injecting genetic manipulation therapy drugs (mRNA) into people, trains their body how to produce a similar spike protein as the bio-weapon.

If they bio-weapon didn't kill someone, or damage them enough to kill them off with other health problems, then the mRNA jabs were designed to finish the job.

Their goal is < 1 billion people on the planet.

Between the bio-weapon, and the mRNA gene "therapy", they figure they can safely reduce the population gradually over the next 3-5 years all while most ignorant people believe it's just a natural plague.

Since SARS-COV2 didn't have a large enough kill, they'll continue to come up with new "pathogens", along with new "vaccines", every 2 years until they finish the job of reducing the population.
beeches

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05/20/2022 09:09 AM

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Re: COVID Clotting mechanism discovered by Swedish Scientists
galloping bump

gallopingk
we only have each other. And that makes us rich.. . .

Wisdom in the man, patience in the wife, brings peace to the house and a happy life.
Throwing you all a bone.
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05/20/2022 09:11 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
 Quoting: Anonymous Coward 72474072


I know people who have this disorder. Diagnosed long before Covid. In some cases it causes life threatening clots. Once diagnosed, usually on thinners for life.
 Quoting: Anonymous Coward 79065706


what's the connection here to S(pike) Protein and blood clotting.
Anonymous Coward
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05/20/2022 09:18 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
 Quoting: Anonymous Coward 72474072


I know people who have this disorder. Diagnosed long before Covid. In some cases it causes life threatening clots. Once diagnosed, usually on thinners for life.
 Quoting: Anonymous Coward 79065706


what's the connection here to S(pike) Protein and blood clotting.
 Quoting: Throwing you all a bone. 72474072


The "S" in Protein S deficiency stands for Seattle. I'm not a scientist, but I do not believe the Protein S you asked about is a spike protein.
Anonymous Coward
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05/20/2022 09:23 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
op

google "protein s deficiency"

tell me what you think.
 Quoting: Anonymous Coward 72474072


I know people who have this disorder. Diagnosed long before Covid. In some cases it causes life threatening clots. Once diagnosed, usually on thinners for life.
 Quoting: Anonymous Coward 79065706


what's the connection here to S(pike) Protein and blood clotting.
 Quoting: Throwing you all a bone. 72474072


The "S" in Protein S deficiency stands for Seattle. I'm not a scientist, but I do not believe the Protein S you asked about is a spike protein.
 Quoting: Anonymous Coward 79065706


S(pike) Protein Causes blood clots

Protein S deficiency causes blood clots.

Do I have to spell it out?
Bogota Colombia

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05/20/2022 09:28 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
they change the things, its the jab that does all of this not that plandemic "virus" they are trying to hide their tracks and make it so that the "virus" did it.

wtf

In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University (LiU), Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The discovery of a possible connection between harmful amyloid production and symptoms of COVID-19 has been published in the Journal of American Chemical Society.
[link to medicalxpress.com (secure)]
-------------------
My synopsis:

-First of all, the American Chemical Society is a huge MAINSTREAM professional organization. The JACS is a peer reviewed journal. These are not conspiracists, they are normal scientists
-Linköping University is one of the biggest universities in Sweden with an emphasis on PhDs.

-When a protein folds into a shape that isn't normal it is called an amyloid. As a result it doesn't act in a normal fashion.
-COVID spike proteins will react to the body's immune system and fold into amyloids
-In another unnatural action the spike protein amyloids join into long chains
-There are 30 other proteins in our body (non COVID related) that can fold this way, and they all lead to unique diseases
--One of these diseases is Alzheimer's, but there are other scary diseases too
-Using computer simulation, the researchers discovered that the coronavirus' spike protein contained seven different sequences which potentially could produce amyloid.
-Three of the seven sequences met the researchers' criteria for being counted as amyloid-producing sequences when experimentally tested. (magic, just like they were designed to do?)
-They produced, among other things, so-called fibrils, which look like long threads when examined under an electron microscope.
-They were able to produce the fibrils in the laboratory environment, but would this happen spontaneously in the body?
-In Alzheimer's the immune system slices and dices large proteins into smaller segments, and then some of the pieces turn into amyloids.
-The researchers were able to show that white blood cells do the same thing to the spike protein.
-A white blood cell type called neutrophils are produced very early after COVID infection, and this is the one that creates the amyloids.
-""We have never seen such perfect, but scary, fibrils as these ones from the amyloid-producing SARS-CoV-2 spike protein and pieces thereof. The fibrils starting from the full-sized spike protein branched out like limbs on a body. Amyloids don't usually branch out like that. We believe that it is due to the characteristics of the spike protein," says Per Hammarström, professor at the Department of Physics, Chemistry and Biology (IFM) at Linköping University." (amazing coincidence)
-Previous research, including a study by South African researchers, has indicated that the spike protein may be involved in the production of small blood clots.
-The blood contains the fibrin protein, which helps the blood to coagulate when a vessel is damaged, so that the hole seals again and stops bleeding. When the injury has begun to heal, the coagulate is supposed to be broken up by plasmin, which is also found in blood.
-The researchers at LiU mixed amyloid-producing protein pieces from the spike protein together with these bodily substances in test tubes, and saw that the fibrin coagulate which was then produced could not be broken down in the usual way by plasmin.
-Disturbed blood coagulation is also seen in many amyloid-related illnesses.
-"We can see that the spike protein, when affected by our own immune system, can produce amyloid structures, and that this can potentially affect our blood coagulation."
-These researchers restrict themselves to talking about micro blood clots, but anyone can see how this could result in huge clots and myocarditis, etc.

(Disclaimer: I was a trauma surgeon, not a research biologist so I am not an expert in this field. And I have been retired for more than 25 years...)
 Quoting: Doctor Congo

Its not the question if we are alone in the universe,its more the question if we are not.
Anonymous Coward
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05/20/2022 09:30 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
...


I know people who have this disorder. Diagnosed long before Covid. In some cases it causes life threatening clots. Once diagnosed, usually on thinners for life.
 Quoting: Anonymous Coward 79065706


what's the connection here to S(pike) Protein and blood clotting.
 Quoting: Throwing you all a bone. 72474072


The "S" in Protein S deficiency stands for Seattle. I'm not a scientist, but I do not believe the Protein S you asked about is a spike protein.
 Quoting: Anonymous Coward 79065706


S(pike) Protein Causes blood clots

Protein S deficiency causes blood clots.

Do I have to spell it out?
 Quoting: Anonymous Coward 72474072

Yes, please. Protein C deficiency, Antithrombin III deficiency and Factor V Leiden also cause blood clotting. I'm not arguing with you, I'm just trying to understand the connection beyond the letter S
Anonymous Coward
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05/20/2022 09:34 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
...


what's the connection here to S(pike) Protein and blood clotting.
 Quoting: Throwing you all a bone. 72474072


The "S" in Protein S deficiency stands for Seattle. I'm not a scientist, but I do not believe the Protein S you asked about is a spike protein.
 Quoting: Anonymous Coward 79065706


S(pike) Protein Causes blood clots

Protein S deficiency causes blood clots.

Do I have to spell it out?
 Quoting: Anonymous Coward 72474072

Yes, please. Protein C deficiency, Antithrombin III deficiency and Factor V Leiden also cause blood clotting. I'm not arguing with you, I'm just trying to understand the connection beyond the letter S
 Quoting: Anonymous Coward 79065706


The PROS1 gene provides instructions for making a protein called protein S that is important for controlling blood clotting. By itself, protein S cannot carry out the chemical reactions necessary for regulating the formation of blood clots. Instead, protein S attaches to certain enzymes and enhances their function. On the basis of this action, protein S is called a cofactor.

Protein S is made chiefly by cells in the liver. The protein circulates in the bloodstream in two forms; it is either attached (bound) to a specific protein or occurs by itself in a free form. Both forms of proteins S can act as cofactors; however, bound protein S is less effective than the free form. Protein S is a cofactor for an enzyme called activated protein C (APC). APC turns off (inactivates) the blood clotting proteins known as factor Va and factor VIIIa. Protein S also helps an enzyme known as tissue factor pathway inhibitor (TFPI) block the activity of another clotting protein, factor Xa.

[link to www.assaygenie.com (secure)]

Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS).

The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Anonymous Coward
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05/20/2022 09:36 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Does that clear it up for YOU?!

Do I have to be the only brains on the forum?!

I'm tired of thinking for all of you idiots.
Anonymous Coward
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05/20/2022 09:38 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


Correct. Back arrow. I am not going to read through "genius" work that does not even consider the basics.
S-man
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05/20/2022 09:43 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Amyloidosis: implicated in Alzheimer's (TDP43 protein), Parkinson's (alpha-synuclein protein) , ALS / Motor Neurone Disease, CJD (prion protein amyloidosis) - amongst others..

WALTZ is an algorithm you can play with sequences to predict how much amyloidosis your Spike protein will cause...

The results are NOT GOOD.



d_senti - sorry for being discombobulated in my posts but here is the output from WALTZ (pictures at the bottom of each page, and I added a ibb.co link too for permanence) for:

Sars-CoV-2 Spike (Wuhan-1):
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

Sars-Cov-2 Spike (Omicron BA.1):
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

Alpha-Synuclein:
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

TDP43:
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

I think it does look a bit depressing, after all...
 Quoting: S-man
FlashBuzzkill

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05/20/2022 09:44 AM

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Re: COVID Clotting mechanism discovered by Swedish Scientists
Pretty creepy when consider hemophilia was the most common genetic defect in the bloodlines of royalty. I wonder if they discovered how to kill us while figuring out how to save themselves?
Gen. John B Gordon and Gen. Nathan Bedford Forrest were the finest citizen-soldiers birthed in America.
Anonymous Coward
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05/20/2022 09:52 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
In patients with serious and long-term COVID-19, disturbed blood coagulation has often been observed. Now, researchers at Linköping University (LiU), Sweden, have discovered that the body's immune system can affect the spike protein on the surface of the SARS-CoV-2 virus, leading to the production of a misfolded spike protein called amyloid. The discovery of a possible connection between harmful amyloid production and symptoms of COVID-19 has been published in the Journal of American Chemical Society.
[link to medicalxpress.com (secure)]
-------------------
My synopsis:

-First of all, the American Chemical Society is a huge MAINSTREAM professional organization. The JACS is a peer reviewed journal. These are not conspiracists, they are normal scientists
-Linköping University is one of the biggest universities in Sweden with an emphasis on PhDs.

-When a protein folds into a shape that isn't normal it is called an amyloid. As a result it doesn't act in a normal fashion.
-COVID spike proteins will react to the body's immune system and fold into amyloids
-In another unnatural action the spike protein amyloids join into long chains
-There are 30 other proteins in our body (non COVID related) that can fold this way, and they all lead to unique diseases
--One of these diseases is Alzheimer's, but there are other scary diseases too
-Using computer simulation, the researchers discovered that the coronavirus' spike protein contained seven different sequences which potentially could produce amyloid.
-Three of the seven sequences met the researchers' criteria for being counted as amyloid-producing sequences when experimentally tested. (magic, just like they were designed to do?)
-They produced, among other things, so-called fibrils, which look like long threads when examined under an electron microscope.
-They were able to produce the fibrils in the laboratory environment, but would this happen spontaneously in the body?
-In Alzheimer's the immune system slices and dices large proteins into smaller segments, and then some of the pieces turn into amyloids.
-The researchers were able to show that white blood cells do the same thing to the spike protein.
-A white blood cell type called neutrophils are produced very early after COVID infection, and this is the one that creates the amyloids.
-""We have never seen such perfect, but scary, fibrils as these ones from the amyloid-producing SARS-CoV-2 spike protein and pieces thereof. The fibrils starting from the full-sized spike protein branched out like limbs on a body. Amyloids don't usually branch out like that. We believe that it is due to the characteristics of the spike protein," says Per Hammarström, professor at the Department of Physics, Chemistry and Biology (IFM) at Linköping University." (amazing coincidence)
-Previous research, including a study by South African researchers, has indicated that the spike protein may be involved in the production of small blood clots.
-The blood contains the fibrin protein, which helps the blood to coagulate when a vessel is damaged, so that the hole seals again and stops bleeding. When the injury has begun to heal, the coagulate is supposed to be broken up by plasmin, which is also found in blood.
-The researchers at LiU mixed amyloid-producing protein pieces from the spike protein together with these bodily substances in test tubes, and saw that the fibrin coagulate which was then produced could not be broken down in the usual way by plasmin.
-Disturbed blood coagulation is also seen in many amyloid-related illnesses.
-"We can see that the spike protein, when affected by our own immune system, can produce amyloid structures, and that this can potentially affect our blood coagulation."
-These researchers restrict themselves to talking about micro blood clots, but anyone can see how this could result in huge clots and myocarditis, etc.

(Disclaimer: I was a trauma surgeon, not a research biologist so I am not an expert in this field. And I have been retired for more than 25 years...)
 Quoting: Doctor Congo


Yup; a poison death injection; plain and simple.

bump
S-man
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05/20/2022 09:53 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Amyloidosis: implicated in Alzheimer's (TDP43 protein), Parkinson's (alpha-synuclein protein) , ALS / Motor Neurone Disease, CJD (prion protein amyloidosis) - amongst others..

WALTZ is an algorithm you can play with sequences to predict how much amyloidosis your Spike protein will cause...

The results are NOT GOOD.



d_senti - sorry for being discombobulated in my posts but here is the output from WALTZ (pictures at the bottom of each page, and I added a ibb.co link too for permanence) for:

Sars-CoV-2 Spike (Wuhan-1):
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

Sars-Cov-2 Spike (Omicron BA.1):
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

Alpha-Synuclein:
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

TDP43:
[link to waltz.switchlab.org (secure)]
[link to ibb.co (secure)]

I think it does look a bit depressing, after all...
 Quoting: S-man

 Quoting: S-man 78104148


The post below is also relevant. Stefanie Seneff has highlighted that the vaccines have enriched 'G' bases (called "Codon Optimisation") which seems to increase the propensity for amyloid.



Well, turns out, swapping the odd base here and there to get the 'same' protein doesn't really work....


[link to ehden.substack.com (secure)]
...In 2011 Nature Medicine magazine published an article called "Breaking the Silence". It described how codon optimization, which uses this synonymous DNA changes, can trigger disease in a number of ways."
[link to doi.org (secure)]

..Turns out the protein which was manufactured when codon optimization has different ways it folds and a different 3D shape, and it "could cause immunogenicity, for example, which wouldn’t be seen until late-stage clinical trials or even after approval".

..The changed form could cause immunogenicity, for example, which wouldn’t be seen until late-stage clinical trials or even after approval." (Chava Kimchi Sarfaty, FDA)
This statement relates to the NORMAL approval cycle. The COVID vaccines went via an accelerated one.

..codon optimization can lead to alterations in protein conformation and function…. and increase immunogenicity….some of these elements can … alter protein folding, and lead to changes in protein conformation and post-translational modifications.” (Vincent P. Mauro)


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BACKGROUND TO ABOVE:
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Remember Stephanie Seneff talked about "Codon Optimisation" - (which the vax manufacturers used to make artificial spike proteins in the human body)?
CODON = three bases, makes an AMINO-ACID.
MORE THAN ONE WAY to make an AMINO-ACID: each position in a CODON can be one of four chemical bases: C,G,T,A, so 4x4x4=64 possible combos; only 20 AMINO-ACIDS.
CODONS have redundancy - more than one CODON for some AMINO-ACIDS.
e.g. Six different ways to Make AMINO ACID arginine: AGA AGG CGG CGA CGN CGC


video:

[link to www.bitchute.com (secure)]

Timestamp:
78m20s: Prions have this "GxxxG" motif; propensiy to form buildups of amyloid. G= Glycine, x= anything.
78m45s: Visual "Spike is a prion-like protein".
Most proteins have 0 GxxxG.
PrP has 14 GxxxG.
Amyloid Beta (Alzheimer's) has 4 GxxxG.
Spike has 7 GxxxG.
note: mRNA in vaccines is enriched with more Guanine in the CODONS, causes excess Glycine GxxxG motifs compared to natural Spike.
G4 Quadruplexes are like building blocks for Amyloid.

80m: When you have lots of Guanine in the CODONS, that's when you get the GxxxG quadruplexes.
81m20s: They form thes elittle squares and then stack up the squares to form a kind of building. Not water soluble; hard to demolish.

82m: Two things I know about that worry me:
Human PrP binds to the G-quadruplexes in its own mRNA, the binding sparks the chain-reaction; misfolded PrP into PrPSc.

83m: Graphic prion mRNA g-quadruplexes (Olsthoorn, Nucleic Acids Research, 2014; 42(14):9327-9333.
Spike may do the same thing, binding to its own mRNA WHICH IS MUCH MORE PREVALENT IN THE VACCINES, than after natural infection!
PrP binding to its own mRNA may be the seed causing PrP to mis-fold into PrPSc.
Important because same mechanism may be involved in Spike binding to its own mRNA - as both present in large numbers when vaccinated!
 Quoting: S-man 80593376
Anonymous Coward
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05/20/2022 09:56 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Walter Chesnut has been writing about amyloidosis of the covid spike protein for several weeks now.

It's very bad news.

He speculates that it causes accelerated aging, among many other horrible things.

[link to wmcresearch.substack.com (secure)]


It's worse for the vaxxed because of all the free floating spikes but occurs in natural infection also.
Bumba
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05/20/2022 10:01 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Clot! stoner
Anonymous Coward
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05/20/2022 10:04 AM
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Re: COVID Clotting mechanism discovered by Swedish Scientists
Those patients vaxxed or unvaxxed?

Article does not say.

hmm
 Quoting: Accidental Stoner


It is from the spike protein in the disease. The journal paper didn't mention vax status. But when the vax's purpose is to produce more spike proteins then I would assume they are at a much greater risk.

Imagine the evil behind a potential engineered disease and a money making vax that quadruples the possibility of death and disability...

And these researches needed to get this report passed the review panel. Any mention of vax status probably would be risky.
 Quoting: Doctor Congo


cool2
Butch DeFeo
Itz The MonkeyPauxCommyUsurpPocalypse

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05/20/2022 10:25 AM

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Re: COVID Clotting mechanism discovered by Swedish Scientists
The Clot Shot = Breakfast of IDIOTS

HER
ENDTHESHUTDOWN77redblueLEDDONTBEAPANDEMICS
Only you can stop the fake pandemic for yourself, no one will ever tell you the pandemic is over. It's time to WIN.
Itz The MonkeyPauxCommyUsurpPocalypse - Pronounced "MONKEY POE COMMY YOU SIR POCKA LIPS"





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