Doctors now prescribing Ketamine ("Special K") for depression and finding amazing results. | |
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Anonymous Coward (OP) User ID: 1313099 United States 02/02/2012 08:02 PM Report Abusive Post Report Copyright Violation | Within 40 minutes, those who received ketamine experienced a significant improvement in depressive symptoms compared with those who took placebo, an improvement that was largest at day two and remained significant through day three. At some point during the course of the trial, 71 percent of participants responded to ketamine and 6 percent responded to placebo. "These findings are particularly noteworthy because a substantial proportion of study participants had been prescribed complex polypharmacy regimens in the past with substantial treatment failures," the authors write. "The mean [average] number of past antidepressant trials was seven, and more than 55 percent of participants failed to respond to electroconvulsive therapy. The toll of this protracted and refractory illness on the subjects was evident, in that two-thirds of participants were on psychiatric disability and nearly all were unemployed." No serious adverse effects were reported during the study. The results lend support to the hypothesis that the glutamatergic system is implicated in the development of bipolar disorder, and that targeting it may lead to improved therapies. "Future research will need to address whether differences in kinetics associated with intravenous administration -- which allows for faster absorption and avoids hepatic metabolism -- are important or necessary for rapid antidepressant effects to occur," the authors write. [link to www.sciencedaily.com] |
Anonymous Coward (OP) User ID: 1313099 United States 02/02/2012 08:03 PM Report Abusive Post Report Copyright Violation | Why Ketamine Produces a Fast Antidepressant Response The drug's robust effect at low doses as a fast-acting antidepressant potentially has use in emergency rooms with high-risk patients. "Ketamine produces a very sharp increase that immediately relieves depression," said Dr. Lisa Monteggia, associate professor of psychiatry at UT Southwestern and senior author of the study published June 15 in Nature. Typical antidepressant medications -- one of the most widely prescribed classes of drugs in the U.S. each year -- often take several weeks to relieve symptoms of depression. If they are not successful within 12 weeks, physicians must prescribe a different antidepressant to produce a response. [link to www.sciencedaily.com] |
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Skin Suit User ID: 4280163 United States 02/02/2012 08:08 PM Report Abusive Post Report Copyright Violation | ketamine will knock you off your feet. i used it a few times in my twenties. it's a PCP derivative chemically. you can't even function normally on it. you just lie on the floor and 40 minutes later you're back to normal. |
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Anonymous Coward User ID: 664728 New Zealand 02/02/2012 08:13 PM Report Abusive Post Report Copyright Violation | Wow I spent my youth in a psych hospital, been on all the psych drugs and had so much thorazine it would literally sedate a horse I used to self medicate heavily used ketamine a few times just before i quit all drugs I thought I just made up my mind to be normal but maybe it was the ketamine? I have been completely normal for over 13 years now--no drugs, no medications, no issues. NONE! I even get up early every day and function I have 2 kids life is great |
Anonymous Coward (OP) User ID: 1313099 United States 02/02/2012 08:14 PM Report Abusive Post Report Copyright Violation | Ketamine: Quick Fix for Severe Depression? Researchers at the Neuro Psychiatric Center next to Ben Taub General Hospital are testing one infusion of ketamine for its short-term effects in treating depression. If the study’s results are successful, a second study will administer ketamine three times a week to patients to test the drug’s long-term effects. “This is supposed to help for a couple months. The study is still under way, so it’s hard for us to know now how long the effects will last. Will it cure depression for a year or longer? I don’t think so. But we’re hoping it will work for a few months in the second trial,” said Dr. Asim Shah, who directs the mood disorder program at Ben Taub General Hospital. Shah said so far the results are promising, but using ketamine to treat depression is not yet FDA approved. Anti-depressants like Prozac or Celexa usually take at least a few weeks to start working. During that time, patients are more susceptible to suicide. [link to abcnews.go.com] |
Anonymous Coward (OP) User ID: 1313099 United States 02/02/2012 08:16 PM Report Abusive Post Report Copyright Violation | Wow Quoting: Anonymous Coward 664728 I spent my youth in a psych hospital, been on all the psych drugs and had so much thorazine it would literally sedate a horse I used to self medicate heavily used ketamine a few times just before i quit all drugs I thought I just made up my mind to be normal but maybe it was the ketamine? I have been completely normal for over 13 years now--no drugs, no medications, no issues. NONE! I even get up early every day and function I have 2 kids life is great that is interesting. maybe it WAS the ketamine...?! |
Anonymous Coward User ID: 9742813 United States 02/02/2012 08:16 PM Report Abusive Post Report Copyright Violation | We use to use it on medical research monkeys at a lab were I worked. I was a technician. Poor hairy bastards were part of long term medical research that stretched on for years. All druggies, constantly strung out or pissy and jonesing. Dogs can't tolerate ketamine well, they got morphine. |
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ScottFlex User ID: 5764516 United States 02/02/2012 08:22 PM Report Abusive Post Report Copyright Violation | Wouldnt weed work better? Minus the munchies and eating then gaining weight and getting even more depressed then smoking more... lol "We must all hang together or surely we will all hang separately." -Benjamin Franklin "Anything you can't say no to is your master, whether its a common addiction or an abusive government..." -ScottFlex |
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Anonymous Coward User ID: 10043482 United States 02/02/2012 08:24 PM Report Abusive Post Report Copyright Violation | all depression and mental illness is demons ... Quoting: where's my stapler i know ive had got it and neerly on the way to curing it ... No its not that is religious bullshit. It is nearly always a spiritual issue, but sometimes a nutritional or body chemical issue. So what the cure of your personal spiritual "demons"? there are some people who are skilled in black magic that can send you some awful thought forms, but again in that case, your spiritual Knowledge of such and how to deal with it, is still your issue. |
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Aphrodite Harmonia User ID: 2119116 United States 02/02/2012 08:36 PM Report Abusive Post Report Copyright Violation | Special K.... meeeeeee-OW! John works 40 hours a week at a factory job. His rate of pay is $12.00 per hour. This week he worked an additional 3.5 hours of overtime for which he is paid $18.00 per hour. If he stops at the bar on the way home and drinks up 40% of his paycheck, how long until his wife piles all his shit up on the sidewalk? |
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Amy_A User ID: 1447484 United States 02/02/2012 08:50 PM Report Abusive Post Report Copyright Violation | Wow Quoting: Anonymous Coward 664728 I spent my youth in a psych hospital, been on all the psych drugs and had so much thorazine it would literally sedate a horse I used to self medicate heavily used ketamine a few times just before i quit all drugs I thought I just made up my mind to be normal but maybe it was the ketamine? I have been completely normal for over 13 years now--no drugs, no medications, no issues. NONE! I even get up early every day and function I have 2 kids life is great Great story friend. Good Luck Peace to you Amy |
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Whiterabbit R.O. User ID: 10053064 United States 02/02/2012 08:58 PM Report Abusive Post Report Copyright Violation | Stuff is probably illegal eh ? Man seriously , i had a cement truck crush my..ahh never mind, anyway i have to take so many pain pills that id love to know what its like NOT to be depressed. Certainly Zoloft and Effexor XR , hasnt really worked . Man to feel happy again ya know like when your were ten and seen what a girl REALLY looks like for the first time , or when she said " sure" for the first date, or like when you opened the letter and said YOUR HIRED for that perfect job, oooooooooooooooooooooooooooooooooooor when your team wins the world series for the first time in 40 some years , in the ninth inning with two outs, yeah he had a 2 -3 count going on also! Yup would be pretty frikin cool , man ! Ahhh lifes good actually, like how can it be bad that god gave ya another day ! Yeah BABY!!! Itz all good |
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