Mystery Fatal Hemorrhagic Disease in Shandong China | |
tosspot User ID: 472746 Australia 07/29/2008 10:17 AM Report Abusive Post Report Copyright Violation | And here's the PROMED Article Archive Number 20080727.2300 Published Date 27-JUL-2008 Subject PRO/AH/EDR> Undiagnosed hemorrhagic disease - China: (Shandong), RFI UNDIAGNOSED HEMORRHAGIC DISEASE - CHINA: (SHANDONG), REQUEST FOR INFORMATION **************************************************************************** A ProMED-mail post < [link to www.promedmail.org>] ProMED-mail is a program of the International Society for Infectious Diseases < [link to www.isid.org>] Date: 27 Jul 2008 From: Stephen O. Cunnion <[email protected]> I received the following email from Chuck Dolejs of the International Association of Emergency Managers regarding a Sound of Hope web page (< [link to en.epochtimes.com] updated [26 Jul 2008]. Has this outbreak been verified by authorities? "China reported that approximately 20 days ago, a man suddenly died from an unidentified disease in Wanjiakou Village, Xiaoguan Town, Wendeng City, Shandong Province. His entire body turned dark purple, and he bled from his mouth, nostrils, ears, and eyes just as he died. Shortly after the man died, 2 other men who been in contact with him, died showing the same symptoms. Villagers who had left the village to work said "3 people died 10 days ago. 6 or 7 more are being treated in the Wendeng Central Hospital. People have been to the area to investigate, but they are unable to classify the disease." Most people outside of the village do not know about the illness. Their families do not want people who have left the village to return. "Reporters from Sound of Hope Radio Network (SOH) interviewed local residents and staff from a health clinic. What follows are transcripts from the recorded interviews. A male villager verified that the disease broke out in the northern section of Wanjiakou Village, and spread rather quickly. The SOH reporter then phoned the Department of Health and Prevention of Contagious Diseases in Wendeng City and Yantai City, Shandong Province using numbers published on the official web sites. However, he was unable to talk with anyone, as the line was either filled with static or the call was routed to a wrong number announcement." [The actual details of the interviews are available at the URL link provided above - Mod.MPP] -- Stephen O. Cunnion, MD, PhD, MPH Medical Director, National Security Health Policy Center The Potomac Institute for Policy Studies 901 N. Stuart Street, Suite 200 Arlington, VA 22203 <[email protected]> [ProMED-mail would like to thank Dr. Stephen Cunnion for sending on this information. As a reminder, it was he who sent ProMED-mail the 1st report on an outbreak of "atypical pneumonia" in Guangdong, China, on 10 Feb 2003 that we posted and was the 1st public notification of the early outbreaks of what was later named Severe Acute Respiratory Sydrome (SARS) (see ProMED-mail posting Pneumonia - China (Guangdong): RFI 20030210.0357 for this report). Using the database of the Global Infectious Disease and Epidemiology Network (GIDEON < [link to gideononline.com>)] to see possible etiologies for a hemorrhagic fever syndrome in China, the most likely diagnosis would be Old World hantavirus infection (57 percent probability), followed by _Streptococcus suis_ infection (40 percent), leptospirosis (1.8 percent) and Crimean-Congo hemorrhagic fever (CCHF -- less than one percent probability). According to the GIDEON database, hantaviruses are endemic in 28 of the 32 provinces, with most cases occurring in the eastern and northeastern provinces (where Shandong is located). Hantaan virus is endemic to Hubei, Heilongjiang, Jiangxi, Jilin and Shanxi. (Fang LQ, Li CY, Yang H, Wu XM, Yang H, Chen HX, Li XW, Cao WC [Using geographic information system to study the association between epidemic areas and main animal hosts of hemorrhagic fever with renal syndrome in China.] Zhonghua Liu Xing Bing Xue Za Zhi 2004 Nov ;25(11):929-33. - 52.2 percent of infections in Hubei are caused by Hantaan virus, and 31.5 percent by Seoul virus. - Most infections in Shandong provin ce are caused by Seoul virus. (Wang ZQ, Wang YL, Fu JH, Zhao L, Sun CY, Zhang XQ, Zhang YX, Fan SZ, Wang ND [Molecular analysis of hantavirus isolated from Shandong province]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 2003 Jun ;17(2):121-3.) - Seoul virus was identified in humans and rodents (_Rattus norvegicus_ and _Mus musculus_) in Beijing during 2003 to 2005. (Zuo SQ, Zhang PH, Jiang JF, Zhan L, Wu XM, Zhao WJ, Wang RM, Tang F, Dun Z, Cao WC. Seoul virus in patients and rodents from Beijing, China. Am J Trop Med Hyg 2008 May ;78(5):833-7. A new Puumala virus subtype, most closely related to strains from Japan and South Korea, has been isolated from bank voles in Northeast China. (2007 publication) (Tang LH, Zhang QF, Xiu MH, Gu GW, Bo S, Yang XD, Liang MF, Li DX [Identification of a new Puumala hantavirus subtype in rodents from China] Bing Du Xue Bao 2007 Jul ;23(4):320-5. The abstract does not give any information about human infection by it. ProMED-mail has reported on hantavirus outbreaks in China earlier this year in Inner Mongolia (see Hantavirus infection - Taiwan ex China (Inner Mongolia) 20080119.0249), and in prior years (see references below) According to the GIDEON database, CCHF has been reported from the southwestern desert region in Xinjiang province and is referred to as Xinjiang fever. Hence it would be a significant geographic change were this outbreak to be due to CCHF. There is also mention that 10 to 20 percent of sheep, goats and cattle in Sichuan are seropositive -- so movement of livestock from the southwest to other provinces may very well move the disease geographically. One should not forget the earlier major outbreaks of _Streptococcus suis_ in China in 2005. A recurrence of the problem is possible. It is noteworthy that according to the question and answer part of the referred media report, there is mention that the cases to date have been in predominantly in men, suggesting that exposure may well be occupational, which places both hantavirus infection and _Streptococcus suis_ as leading possibilities for the etiologic agent for this outbreak. The outbreak is occurring in a rural zone where there is a high likelihood of exposure of males to rodents and to the porcine population during usual occupational activities in an agricultural zone. ProMED-mail would greatly appreciate more information from knowledgeable sources in the region on this as yet unsubstantiated report of a cluster of hemorrhagic-like illnesses with fatalities in Shandong Province. For a map of China with geographic divisions see < [link to www.lib.utexas.edu] Of note, Shanjong province is contiguously north of Jiangsu province, where there was an outbreak of 'epidemic hemorrhagic fever' in 2007, which while the etiologic agent was not mentioned, was felt to most likely be due to an Old World hantavirus infection (see prior ProMED-mail postings Epidemic hemorrhagic fever - China (Jiangsu) 20070113.0179 and Epidemic hemorrhagic fever - China (Jiangsu) (02) 20070116.0206). The interactive HealthMap/ProMED map of China can be accessed at < [link to healthmap.org] This map provides links to other recent ProMED-mail postings on events occurring in China and neighboring countries. - Mod.MPP] [Seoul virus occurs worldwide and is unlikely to be associated with a localized outbreak in China. Puumala virus is prevalent throughout northern Europe and middle Asia and is usually responsible for only mild forms of hemorragic fever with renal syndrome (HFRS). - Mod.CP] [see also: Hantavirus infection - Taiwan ex China (Inner Mongolia) 20080119.0249 2007 ---- Streptococcus suis, human - China (Guangdong) 20070726.2411 Streptococcus suis - China (Hong Kong) 20070517.1573 Streptococcus suis - China (Hong Kong)(02) 20070527.1707 Epidemic hemorrhagic fever - China (Jiangsu) 20070113.0179 Epidemic hemorrhagic fever - China (Jiangsu) (02) 20070116.0206 2006 ---- Streptococcus suis, porcine, human, 2005 - China (... 20060411.1082 2005 ---- Hemorrhagic fever - China (Inner Mongolia) 20050701.1863 Streptococcus suis, human - China (Hong Kong) 20050728.2196 Streptococcus suis, porcine, human - China 20050730.2217 Streptococcus suis, porcine, human - China (20) 20051024.3099 Streptococcus suis, porcine, human - China (Sichuan) (02) 20050728.2194 Streptococcus suis, porcine, human - China (Sichuan) 20050727.2179 2000 ---- Hantavirus infection - China (Chongqing) (02) 20001121.2020 Hantavirus infection - China (Chongqing): alert 20001117.2008 Hantavirus infection - China: background 20001118.2015 Hantavirus infection - China: background (02) 20001126.2056 Hantavirus infection - China: background (03) 20001206.2127 1999 ---- Strep. suis, human infection - China (Hong Kong) 19991009.1810 1998 ---- Hantavirus infection - China (Hong Kong) 19980412.0670 Hemorrhagic fever, epidemic warning - China 19980905.1782 1997 ---- Hemorrhagic fever with renal syndrome - S.E. Asia 19970408.0743] ...............................mpp/ejp/jw [link to www.promedmail.org] |
The Analog Guy User ID: 74180 United States 07/29/2008 10:50 AM Report Abusive Post Report Copyright Violation | Crap that's scary!!! Morphed hanta virus....Ebola anyone? I say burn all of your bridges while you still have control of the flame. We are like flies crawling across the ceiling of the Sistine Chapel: We cannot see what angels and gods lie underneath the threshold of our perceptions. We do not live in reality; we live in our paradigms, our habituated perceptions, our illusions; the illusions we share through culture we call reality, but the true historical reality of our condition is invisible to us.” |
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DeKay User ID: 405769 United States 07/29/2008 11:08 AM Report Abusive Post Report Copyright Violation | At the winter Olympics I said to my husband as I saw scores of people now that's a way to spread a lethal virus. I still think it is. What better way to infect the entire world all in one setting? Given the incubation time would be just enough for everyone to get sick, be asymptomatic and then get on a plane and take it home to spread. It takes just one person with an airborne virulent disease to walk through a crowd and infect everyone. Depopulation problem - SOLVED! |
Anonymous Coward User ID: 430535 United States 07/29/2008 11:10 AM Report Abusive Post Report Copyright Violation | |
tosspot User ID: 472746 Australia 07/29/2008 11:15 AM Report Abusive Post Report Copyright Violation | Crap that's scary!!! Morphed hanta virus....Ebola anyone? Quoting: The Analog GuyEbola outbreaks happen more often than most people think. example of ebola case ,this one is dated 4 june 2008 The PROMED Site is a reporting site used by ppl from the science, medico communities to the CDC and WHO and is really good for keeping track of outbreaks As i said on a previous post don't look around on this site too much as it will scare you Archive Number 20080604.1790 Published Date 04-JUN-2008 Subject PRO/ERR> Ebola hemorrhagic fever - Congo DR: susp., corr. EBOLA HEMORRHAGIC FEVER - CONGO DR: SUSPECTED, CORRECTION ********************************************************* A ProMED-mail post [link to www.promedmail.org] ProMED-mail is a program of the International Society for Infectious Diseases [link to www.isid.org] [Re: ProMED-mail post Ebola hemorrhagic fever - Congo DR: susp 20080603.1779, Maia Funk-Baumann, MD of the WHO Collaborating Centre for Travellers' Health at the University of Zurich has pointed out that this suspected Ebola case is from Boende, in the northwestern province of Equateur, not Kasai Occidental province as stated in the moderator's comment. Accordingly, this post has been revised to take account of the error. Dr Funk-Baumann's help is appreciated. - Mod.CP] Date: Tue 3 Jun 2008 Source: Radio Okapi online [trans. from French, edited] < [link to www.radiookapi.net] A case of hemorrhagic fever has been reported in the Boende health zone of Tshuapa District. The chief medical officer in the area, Dr. Cesar Moyeli, believes that symptoms exhibited by a woman admitted to a general hospital in the zone are consistent with those of Ebola hemorrhagic fever. Dr. Moyeli stated that: "After 2 days, the patient began to experience hemorrhage: 1st from the genitalia, then from her eyes, gums and even her ears. In addition, red patches appeared on her skin. Taken together, these features suggested a diagnosis of hemorrhagic fever. In order to avoid disseminating the infection, we informed the family that, due to the danger of the illness, the body could not be released to the family for normal burial. Instead, the body was disinfected and taken directly to the cemetery for burial. All materials used in the care of the patient have been burnt, and the treatment room remains closed." The patient died last Thursday [29 May 2008]. Clinical samples have been taken and dispatched to Kinshasa [the capital of Congo DR] for virus identification. Meanwhile, the family of the deceased and all her known contacts will be kept under observation for a period of 3 weeks. -- Communicated by: ProMED-mail <[email protected]> [Confirmation of the diagnosis is awaited. A map of The Democratic Republic of Congo (Congo DR) showing Boende in Equateur province can be accessed at: < [link to www.un.org] The 2007 outbreak of Ebola hemorrhagic fever in Congo DR occurred to the south in Kasai Occidental province; see ProMED refs. below. - Mod.CP] [see also: Ebola hemorrhagic fever - Congo DR: susp 20080603.1779 2007 ---- Ebola hemorrhagic fever - Congo DR (13) 20071121.3758 Ebola hemorrhagic fever - Congo DR (11): WHO 20071003.3270 Ebola hemorrhagic fever - Congo DR (10) 20071003.3265 Ebola hemorrhagic fever - Congo DR (09) 20071001.3245 Ebola hemorrhagic fever - Congo DR (09): WHO 20070927.3204 Ebola hemorrhagic fever - Congo DR (08) 20070926.3191 Ebola hemorrhagic fever - Congo DR (07) 20070923.3156 Ebola hemorrhagic fever - Congo DR (06) 20070921.3138 Ebola hemorrhagic fever - Congo DR (05): WHO 20070920.3132 Ebola hemorrhagic fever - Congo DR (04) 20070916.3076 Ebola hemorrhagic fever - Congo DR (03): WHO 20070914.3049 Ebola hemorrhagic fever - Congo DR (02) 20070912.3026 Ebola hemorrhagic fever - Congo DR 20070910.2996 2006 ---- Ebola hemorrhagic fever - Congo DR: susp. 20060315.0806 1999 ---- Hemorrhagic fever NOT Ebola - Congo, DR 19990505.0742 Hemorrhagic fever, Ebola suspected - Congo, DR (03) 19990504.0732] .....................................................cp/msp/jw |
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